HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T00T99	S-adenosylhomocysteine hydrolase-like protein 1	AHCYL1	O43865	1 Reference(s)
T21CMG	Hepcidin	HAMP	P81172	2 Reference(s)
T20RA0	Adenosine deaminase	ADA	P00813	1 Reference(s)
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	3 Reference(s)
T90ZKN	Cathepsin B	CTSB	P07858	1 Reference(s)
T70OGQ	Sodium/potassium-transporting ATPase subunit alpha-1	ATP1A1	P05023	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	4 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	1 Reference(s)
T73EVE	Cyclic AMP-dependent transcription factor ATF-2	ATF2	P15336	1 Reference(s)
T75B9S	Cyclic AMP-responsive element-binding protein 1	CREB1	P16220	1 Reference(s)
T45G32	Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	1 Reference(s)
T34FQX	Protein kinase C zeta type	PRKCZ	Q05513	1 Reference(s)
T74QOR	Tyrosine-protein kinase JAK3	JAK3	P52333	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	1 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	1 Reference(s)
T57L0X	Oxysterols receptor LXR-alpha	NR1H3	Q13133	1 Reference(s)
T68XXK	4-aminobutyrate aminotransferase, mitochondrial	ABAT	P80404	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T57HGP	Tumor necrosis factor receptor superfamily member 6	FAS	P25445	1 Reference(s)
T32KN9	Alpha-amylase 1A	AMY1A	P0DUB6	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	3 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	2 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	6 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	14 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	1 Reference(s)
T31MUM	5,6-dihydroxyindole-2-carboxylic acid oxidase	TYRP1	P17643	1 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T22NX4	Toll-like receptor 2	TLR2	O60603	1 Reference(s)
T76QBQ	CREB-regulated transcription coactivator 2	CRTC2	Q53ET0	1 Reference(s)
T77PFO	Histone deacetylase 6	HDAC6	Q9UBN7	1 Reference(s)
T70HTD	Cytochrome P450 2E1	CYP2E1	P05181	2 Reference(s)
T80OPZ	NADPH oxidase 4	NOX4	Q9NPH5	2 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	2 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T34Y8V	Oxysterols receptor LXR-beta	NR1H2	P55055	1 Reference(s)
T25RTY	C-C motif chemokine 22	CCL22	O00626	1 Reference(s)
T77O2V	Mannose-1-phosphate guanyltransferase beta	GMPPB	Q9Y5P6	1 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	4 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	8 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	4 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	5 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	2 Reference(s)
T24U57	E-selectin	SELE	P16581	1 Reference(s)
T72BXP	Platelet endothelial cell adhesion molecule	PECAM1	P16284	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	2 Reference(s)
T88QQE	Fibroblast growth factor 2	FGF2	P09038	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	10 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	4 Reference(s)
T39YUJ	Tyrosine-protein phosphatase non-receptor type 6	PTPN6	P29350	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	2 Reference(s)
T20H9F	Stromelysin-1	MMP3	P08254	1 Reference(s)
T95H9O	Stromelysin-2	MMP10	P09238	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	4 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	4 Reference(s)
T38OH4	Caspase-1	CASP1	P29466	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	2 Reference(s)
T32UNL	Lens fiber major intrinsic protein	MIP	P30301	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T64UH1	Nitric oxide synthase, endothelial	NOS3	P29474	2 Reference(s)
T22H8P	Carbonic anhydrase 3	CA3	P07451	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	2 Reference(s)
T30D9G	Superoxide dismutase [Cu-Zn]	SOD1	P00441	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	2 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	2 Reference(s)
T80XW6	Scavenger receptor class B member 1	SCARB1	Q8WTV0	1 Reference(s)
T02DEN	Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide	GCG	P01275	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	2 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	2 Reference(s)
T01HJQ	Calreticulin	CALR	P27797	1 Reference(s)
T86J48	Sodium/glucose cotransporter 1	SLC5A1	P13866	2 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	3 Reference(s)
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	3 Reference(s)
T41BYM	Fibroblast growth factor 23	FGF23	Q9GZV9	1 Reference(s)
T85CC2	Peptidyl-prolyl cis-trans isomerase D	PPID	Q08752	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	2 Reference(s)
T77FOL	Neuromodulin	GAP43	P17677	1 Reference(s)
T00CXT	Prostaglandin G/H synthase 1	PTGS1	P23219	1 Reference(s)
T27U96	Granulocyte-macrophage colony-stimulating factor	CSF2	P04141	1 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	1 Reference(s)
T02GD4	Tumor necrosis factor ligand superfamily member 6	FASLG	P48023	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T22IMH	Cyclin-dependent kinase 6	CDK6	Q00534	1 Reference(s)
T38BR0	G1/S-specific cyclin-D2	CCND2	P30279	1 Reference(s)
T75H3W	Cyclin-dependent kinase 2	CDK2	P24941	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T04UTZ	G1/S-specific cyclin-E1	CCNE1	P24864	1 Reference(s)
T53ES3	Protein S100-A1	S100A1	P23297	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	1 Reference(s)
T04A6O	UDP-glucuronosyltransferase 1A3	UGT1A3	P35503	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	1 Reference(s)
T14LSK	E3 ubiquitin-protein ligase XIAP	XIAP	P98170	1 Reference(s)
T91OUC	Mucin-5AC	MUC5AC	P98088	1 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	1 Reference(s)
T64X48	C-X-C chemokine receptor type 4	CXCR4	P61073	1 Reference(s)
T61OY3	UDP-glucuronosyltransferase 1A1	UGT1A1	P22309	1 Reference(s)
T37WQE	Kallikrein-5	KLK5	Q9Y337	1 Reference(s)
T16DCZ	Twist-related protein 1	TWIST1	Q15672	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T51EKP	Apolipoprotein M	APOM	O95445	1 Reference(s)
T07VV7	Guanylin	GUCA2A	Q02747	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T80WPU	Protein ABHD15	ABHD15	Q6UXT9	1 Reference(s)
T56OUM	14-3-3 protein zeta/delta	YWHAZ	P63104	1 Reference(s)
T24YWQ	Insulin-degrading enzyme	IDE	P14735	1 Reference(s)
T34HYH	Interleukin-1 alpha	IL1A	P01583	1 Reference(s)
T04V7K	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7	ENPP7	Q6UWV6	1 Reference(s)
T51U9M	Carnitine O-palmitoyltransferase 1, muscle isoform	CPT1B	Q92523	1 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	1 Reference(s)
T50GQE	Interleukin-13	IL13	P35225	1 Reference(s)
T70HC9	Hepatocyte nuclear factor 1-alpha	HNF1A	P20823	1 Reference(s)
T49J7I	Hepatocyte nuclear factor 4-alpha	HNF4A	P41235	1 Reference(s)
T67RBZ	Mitochondrial uncoupling protein 2	UCP2	P55851	1 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	1 Reference(s)
T89GCM	Inward rectifier potassium channel 2	KCNJ2	P63252	1 Reference(s)
T90XYZ	C-reactive protein	CRP	P02741	1 Reference(s)
T43Y5O	D(3) dopamine receptor	DRD3	P35462	1 Reference(s)
T44S1A	Apolipoprotein A-I	APOA1	P02647	1 Reference(s)
T74P7I	G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	1 Reference(s)
T68WYW	von Willebrand factor	VWF	P04275	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	1 Reference(s)

Herb ID: H0715	Chinese Character: 车前子
English Name: seed of asiatic pantain	Latin Name: Plantago asiatica
Chinese Pin Yin : Che Qian Zi	TCM-ID: TCMH241
Therapeutic Function in Chinese : 利水渗湿	Therapeutic Function in English: For promoting diuresis and penetrating dampness
Herb Function: Remove heat, cause diuresis and eliminate damp, relieve dysuria, clear the eye, and promote expectoration

Herb Description

Related Targets (Total: 137)

Related Compounds (Total: 15)