Herb ID: H0715 | Chinese Character: 车前子 |
English Name: seed of asiatic pantain | Latin Name: Plantago asiatica |
Chinese Pin Yin : Che Qian Zi | TCM-ID: TCMH241 |
Therapeutic Function in Chinese : 利水渗湿 | Therapeutic Function in English: For promoting diuresis and penetrating dampness |
Herb Function: Remove heat, cause diuresis and eliminate damp, relieve dysuria, clear the eye, and promote expectoration |
Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
---|---|---|---|---|
T00T99 | S-adenosylhomocysteine hydrolase-like protein 1 | AHCYL1 |
O43865 |
1 Reference(s) |
T21CMG | Hepcidin | HAMP |
P81172 |
2 Reference(s) |
T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
3 Reference(s) |
T90ZKN | Cathepsin B | CTSB |
P07858 |
1 Reference(s) |
T70OGQ | Sodium/potassium-transporting ATPase subunit alpha-1 | ATP1A1 |
P05023 |
1 Reference(s) |
T83YZD | Acetylcholinesterase | ACHE |
P22303 |
4 Reference(s) |
T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
T73EVE | Cyclic AMP-dependent transcription factor ATF-2 | ATF2 |
P15336 |
1 Reference(s) |
T75B9S | Cyclic AMP-responsive element-binding protein 1 | CREB1 |
P16220 |
1 Reference(s) |
T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
T34FQX | Protein kinase C zeta type | PRKCZ |
Q05513 |
1 Reference(s) |
T74QOR | Tyrosine-protein kinase JAK3 | JAK3 |
P52333 |
1 Reference(s) |
T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
2 Reference(s) |
T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
T57L0X | Oxysterols receptor LXR-alpha | NR1H3 |
Q13133 |
1 Reference(s) |
T68XXK | 4-aminobutyrate aminotransferase, mitochondrial | ABAT |
P80404 |
1 Reference(s) |
T01QLH | Estrogen receptor | ESR1 |
P03372 |
1 Reference(s) |
T57HGP | Tumor necrosis factor receptor superfamily member 6 | FAS |
P25445 |
1 Reference(s) |
T32KN9 | Alpha-amylase 1A | AMY1A |
P0DUB6 |
1 Reference(s) |
T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
3 Reference(s) |
T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
6 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
14 Reference(s) |
T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
T31MUM | 5,6-dihydroxyindole-2-carboxylic acid oxidase | TYRP1 |
P17643 |
1 Reference(s) |
T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
T77PFO | Histone deacetylase 6 | HDAC6 |
Q9UBN7 |
1 Reference(s) |
T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
2 Reference(s) |
T80OPZ | NADPH oxidase 4 | NOX4 |
Q9NPH5 |
2 Reference(s) |
T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
2 Reference(s) |
T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
2 Reference(s) |
T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
1 Reference(s) |
T34Y8V | Oxysterols receptor LXR-beta | NR1H2 |
P55055 |
1 Reference(s) |
T25RTY | C-C motif chemokine 22 | CCL22 |
O00626 |
1 Reference(s) |
T77O2V | Mannose-1-phosphate guanyltransferase beta | GMPPB |
Q9Y5P6 |
1 Reference(s) |
T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
4 Reference(s) |
T44LWL | Transcription factor p65 | RELA |
Q04206 |
8 Reference(s) |
T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
4 Reference(s) |
T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
5 Reference(s) |
T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
T24U57 | E-selectin | SELE |
P16581 |
1 Reference(s) |
T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 |
P16284 |
1 Reference(s) |
T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
2 Reference(s) |
T88QQE | Fibroblast growth factor 2 | FGF2 |
P09038 |
1 Reference(s) |
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
10 Reference(s) |
T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
4 Reference(s) |
T39YUJ | Tyrosine-protein phosphatase non-receptor type 6 | PTPN6 |
P29350 |
1 Reference(s) |
T80OJF | Interstitial collagenase | MMP1 |
P03956 |
1 Reference(s) |
T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
2 Reference(s) |
T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
T95H9O | Stromelysin-2 | MMP10 |
P09238 |
1 Reference(s) |
T38T1U | Caspase-8 | CASP8 |
Q14790 |
4 Reference(s) |
T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
4 Reference(s) |
T38OH4 | Caspase-1 | CASP1 |
P29466 |
1 Reference(s) |
T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
2 Reference(s) |
T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
2 Reference(s) |
T22H8P | Carbonic anhydrase 3 | CA3 |
P07451 |
1 Reference(s) |
T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
2 Reference(s) |
T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
1 Reference(s) |
T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
2 Reference(s) |
T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
2 Reference(s) |
T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
1 Reference(s) |
T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG |
P01275 |
1 Reference(s) |
T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
2 Reference(s) |
T01HJQ | Calreticulin | CALR |
P27797 |
1 Reference(s) |
T86J48 | Sodium/glucose cotransporter 1 | SLC5A1 |
P13866 |
2 Reference(s) |
T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
3 Reference(s) |
T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
3 Reference(s) |
T41BYM | Fibroblast growth factor 23 | FGF23 |
Q9GZV9 |
1 Reference(s) |
T85CC2 | Peptidyl-prolyl cis-trans isomerase D | PPID |
Q08752 |
1 Reference(s) |
T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
2 Reference(s) |
T77FOL | Neuromodulin | GAP43 |
P17677 |
1 Reference(s) |
T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
1 Reference(s) |
T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
1 Reference(s) |
T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
1 Reference(s) |
T22IMH | Cyclin-dependent kinase 6 | CDK6 |
Q00534 |
1 Reference(s) |
T38BR0 | G1/S-specific cyclin-D2 | CCND2 |
P30279 |
1 Reference(s) |
T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
1 Reference(s) |
T75HMM | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 |
Q07820 |
1 Reference(s) |
T04UTZ | G1/S-specific cyclin-E1 | CCNE1 |
P24864 |
1 Reference(s) |
T53ES3 | Protein S100-A1 | S100A1 |
P23297 |
1 Reference(s) |
T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
T04A6O | UDP-glucuronosyltransferase 1A3 | UGT1A3 |
P35503 |
1 Reference(s) |
T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
T14LSK | E3 ubiquitin-protein ligase XIAP | XIAP |
P98170 |
1 Reference(s) |
T91OUC | Mucin-5AC | MUC5AC |
P98088 |
1 Reference(s) |
T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
T64X48 | C-X-C chemokine receptor type 4 | CXCR4 |
P61073 |
1 Reference(s) |
T61OY3 | UDP-glucuronosyltransferase 1A1 | UGT1A1 |
P22309 |
1 Reference(s) |
T37WQE | Kallikrein-5 | KLK5 |
Q9Y337 |
1 Reference(s) |
T16DCZ | Twist-related protein 1 | TWIST1 |
Q15672 |
1 Reference(s) |
T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
T30VNV | Myeloperoxidase | MPO |
P05164 |
1 Reference(s) |
T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
T04V7K | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | ENPP7 |
Q6UWV6 |
1 Reference(s) |
T51U9M | Carnitine O-palmitoyltransferase 1, muscle isoform | CPT1B |
Q92523 |
1 Reference(s) |
T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
1 Reference(s) |
T50GQE | Interleukin-13 | IL13 |
P35225 |
1 Reference(s) |
T70HC9 | Hepatocyte nuclear factor 1-alpha | HNF1A |
P20823 |
1 Reference(s) |
T49J7I | Hepatocyte nuclear factor 4-alpha | HNF4A |
P41235 |
1 Reference(s) |
T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 |
P55851 |
1 Reference(s) |
T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
1 Reference(s) |
T89GCM | Inward rectifier potassium channel 2 | KCNJ2 |
P63252 |
1 Reference(s) |
T90XYZ | C-reactive protein | CRP |
P02741 |
1 Reference(s) |
T43Y5O | D(3) dopamine receptor | DRD3 |
P35462 |
1 Reference(s) |
T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
1 Reference(s) |
T68WYW | von Willebrand factor | VWF |
P04275 |
1 Reference(s) |
T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
T38EQ6 | NAD(P)H dehydrogenase [quinone] 1 | NQO1 |
P15559 |
1 Reference(s) |