Compound Description
| ID: C1030 | Common name: Aucubin |
| IUPAC: (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | CAS: CAS:479-98-1 |
| Chembl ID: CHEMBL514882 | Pubchem ID: CID:91458 |
| Formula: C15H22O9 | TCM-ID: TCMC747 |
| Smiles: C1=COC(C2C1C(C=C2CO)O)OC3C(C(C(C(O3)CO)O)O)O | |
| Alias:
Aucubin;
β-D-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl, [1S-(1α,4aα,5α,7aα)]-; (1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl β-D-glucopyranoside; Acubin; Aucubine; Aucubosid; Aucuboside; Rhimantin |
Structure:
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Related Targets (Total: 9)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
B | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
B | 1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
C | 1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
C | 1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
C | 1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
C | 1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 18)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1118 | Bai Ji | 白芨 | Common bletilla | Bletilla striata |
| H0718 | Yang Jiao Qi | 羊角七 | NA | Bletilla striata |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0713 | Che Qian Cao | 车前草 | all-grass of rippleseed plantain | Plantago depressa |
| H0867 | Chuan Deng Xin Cao | 川灯心草 | Common rush | Juncus effusus |
| H0193 | Ma Bian Cao | 马鞭草 | European verbena | Verbena officinalis |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0688 | Xuan Shen | 玄参 | Ningpo figwort | Scrophularia ningpoensis |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H0964 | Deng Xin Cao | 灯心草 | Common rush | Juncus effusus |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H0715 | Che Qian Zi | 车前子 | seed of asiatic pantain | Plantago asiatica |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H0768 | Yuan Shen | 元参 | Figwort root | Scrophularia ningpoensis |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
Ckey description of the interaction between compound and target