| ID: C1207 | Common name: Calcitriol | 
| IUPAC: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol | CAS: CAS:32222-06-3 | 
| Chembl ID: CHEMBL846 | Pubchem ID: CID:5280453 | 
| Formula: C27H44O3 | TCM-ID: TCMC854 | 
| Smiles: O[C@H]1C[C@H](O)C(=C)/C(=C\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(O)(C)C)C)C)/C1 | |
| Alias: 
                        
                        9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1α,3β,5Z,7E)-; (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol; 1,25-Dihydroxycholecalciferol; 1,25-Dihydroxyvitamin D; 1,25-Dihydroxyvitamin D3; 1a,25-Dihydroxyvitamin D3; 1α,25-(OH)2D3; 1α,25-Dihydroxycholecalciferol; 1α,25-Dihydroxyvitamin D3; 1α,25-Hydroxyl-vitamin D3; Calcijex; Calcitriol; DN 101; Dihydroxyvitamin D3; Panbonis; Ro 21-5535; Rocaltrol; Silkis; Solbone P; Soltriol; Topitriol; Toptriol | Structure:   | 
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence | 
|---|---|---|---|---|---|
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA | P25963 | A | 1 Reference(s) | 
| T34ZK4 | Glutathione hydrolase 1 proenzyme | GGT1 | P19440 | A | 1 Reference(s) | 
| T41BYM | Fibroblast growth factor 23 | FGF23 | Q9GZV9 | A | 3 Reference(s) | 
| T85JI5 | Vitamin D3 receptor | VDR | P11473 | A | 11 Reference(s) | 
| T55J1X | Radiation-inducible immediate-early gene IEX-1 | IER3 | P46695 | A | 1 Reference(s) | 
| T38FFJ | Potassium voltage-gated channel subfamily H member 1 | KCNH1 | O95259 | B | 1 Reference(s) | 
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | P19838 | B | 1 Reference(s) | 
| T11BI7 | Toll-like receptor 4 | TLR4 | O00206 | B | 1 Reference(s) | 
| T05DRQ | Receptor tyrosine-protein kinase erbB-4 | ERBB4 | Q15303 | B | 1 Reference(s) | 
| T15URL | Cathelicidin antimicrobial peptide | CAMP | P49913 | B | 2 Reference(s) | 
| T59Y35 | Advanced glycosylation end product-specific receptor | AGER | Q15109 | B | 2 Reference(s) | 
| T91MKC | Runt-related transcription factor 2 | RUNX2 | Q13950 | B | 1 Reference(s) | 
| T37YKZ | Endothelin receptor type B | EDNRB | P24530 | C | 1 Reference(s) | 
| T09ICL | Transient receptor potential cation channel subfamily V member 6 | TRPV6 | Q9H1D0 | C | 1 Reference(s) | 
| T56TFE | 5'-nucleotidase | NT5E | P21589 | C | 1 Reference(s) | 
| T88UDX | Lysine-specific demethylase 6B | KDM6B | O15054 | C | 1 Reference(s) | 
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 | P09917 | C | 1 Reference(s) | 
| T80TUC | Apoptosis regulator BAX | BAX | Q07812 | C | 1 Reference(s) | 
| T75U40 | Cytotoxic T-lymphocyte protein 4 | CTLA4 | P16410 | C | 1 Reference(s) | 
| T33JS5 | CCN family member 2 | CCN2 | P29279 | C | 1 Reference(s) | 
| T74GHX | OX-2 membrane glycoprotein | CD200 | P41217 | C | 1 Reference(s) | 
| T37WQE | Kallikrein-5 | KLK5 | Q9Y337 | C | 1 Reference(s) | 
| T84W8G | Aryl hydrocarbon receptor | AHR | P35869 | C | 1 Reference(s) | 
| T01QLH | Estrogen receptor | ESR1 | P03372 | C | 1 Reference(s) | 
| T85AXP | Cytochrome P450 3A4 | CYP3A4 | P08684 | C | 1 Reference(s) | 
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 | P01137 | C | 1 Reference(s) | 
| T64LXU | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | CYP24A1 | Q07973 | C | 1 Reference(s) | 
| T38TP1 | Sodium-dependent phosphate transporter 2 | SLC20A2 | Q08357 | C | 1 Reference(s) | 
| T68EEP | Phospholipase D1 | PLD1 | Q13393 | C | 1 Reference(s) | 
| T47K8G | Podocalyxin | PODXL | O00592 | C | 1 Reference(s) | 
| T55JB4 | Fibroblast growth factor receptor 1 | FGFR1 | P11362 | C | 1 Reference(s) | 
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG | P37231 | C | 1 Reference(s) | 
| T06AO4 | Membrane cofactor protein | CD46 | P15529 | C | 1 Reference(s) | 
| T82P0Z | Renin | REN | P00797 | C | 1 Reference(s) | 
| T47WT6 | Breast cancer type 1 susceptibility protein | BRCA1 | P38398 | C | 1 Reference(s) | 
| T52I9S | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | CYP27B1 | O15528 | C | 1 Reference(s) |