HIT-result

Type	Detail
Target ID	T88UDX
Protein Name	Lysine-specific demethylase 6B
Uniprot ID	O15054
Protein Name Alias	EC 1.14.11.68; JmjC domain-containing protein 3; Jumonji domain-containing protein 3; Lysine demethylase 6B
Gene ID	23135
Gene Symbol	KDM6B
Gene Alias	JMJD3; KIAA0346
TTD	T56057: Research target
Pfam	PF02373
GO	0005634:nucleus 0070301:cellular response to hydrogen peroxide 0120162:positive regulation of cold-induced thermogenesis 0010468:regulation of gene expression 0045446:endothelial cell differentiation 0048333:mesodermal cell differentiation 0051213:dioxygenase activity 0055007:cardiac muscle cell differentiation 0031490:chromatin DNA binding 0007507:heart development 0045165:cell fate commitment 0071558:histone demethylase activity (H3-K27 specific) 0060992:response to fungicide 0002437:inflammatory response to antigenic stimulus 0021766:hippocampus development 0071557:histone H3-K27 demethylation 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 0046872:metal ion binding 0006338:chromatin remodeling 0045944:positive regulation of transcription by RNA polymerase II 0014823:response to activity 0008013:beta-catenin binding 0044666:MLL3/4 complex
PDB	6F6D ; 5FP3 ; 4ASK ; 5OY3 ; 2XUE ; 2XXZ
Drugbank	NA
KEGG	hsa:23135

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description