HIT-result

Type	Detail
Target ID	T52I9S
Protein Name	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Uniprot ID	O15528
Protein Name Alias	EC 1.14.15.18; 25-OHD-1 alpha-hydroxylase; 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; VD3 1A hydroxylase; Calcidiol 1-monooxygenase; Cytochrome P450 subfamily XXVIIB polypeptide 1; Cytochrome P450C1 alpha; Cytochrome P450VD1-alpha; Cytochrome p450 27B1
Gene ID	1594
Gene Symbol	CYP27B1
Gene Alias	CYP1ALPHA; CYP27B
TTD	NA
Pfam	PF00067
GO	0062185:secalciferol 1-monooxygenase activity 0036378:calcitriol biosynthetic process from calciol 0034341:response to interferon-gamma 0055074:calcium ion homeostasis 0033280:response to vitamin D 0010980:positive regulation of vitamin D 24-hydroxylase activity 0043627:response to estrogen 0032496:response to lipopolysaccharide 0042369:vitamin D catabolic process 0030308:negative regulation of cell growth 0006816:calcium ion transport 0045618:positive regulation of keratinocyte differentiation 0070564:positive regulation of vitamin D receptor signaling pathway 0005737:cytoplasm 0030282:bone mineralization 0004498:calcidiol 1-monooxygenase activity 0042359:vitamin D metabolic process 0046697:decidualization 0010956:negative regulation of calcidiol 1-monooxygenase activity 0005506:iron ion binding 0020037:heme binding 0030500:regulation of bone mineralization 0005741:mitochondrial outer membrane 0005739:mitochondrion 0070314:G1 to G0 transition 0006766:vitamin metabolic process 0008285:negative regulation of cell population proliferation
PDB	NA
Drugbank	DB00153 ; DB11094 ; DB01285 ; DB01436 ; DB00146
KEGG	hsa:1594

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Name: Calcitriol

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Name: Cholecalciferol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens