HIT-result

Type	Detail
Target ID	T55JB4
Protein Name	Fibroblast growth factor receptor 1
Uniprot ID	P11362
Protein Name Alias	FGFR-1; EC 2.7.10.1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD antigen CD331
Gene ID	2260
Gene Symbol	FGFR1
Gene Alias	BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
TTD	T47101: Successful target
Pfam	PF00047 ; PF07679 ; PF07714 ; PF18123
GO	0048705:skeletal system morphogenesis 0004713:protein tyrosine kinase activity 0043410:positive regulation of MAPK cascade 0000165:MAPK cascade 0045597:positive regulation of cell differentiation 0016021:integral component of membrane 0005524:ATP binding 0001837:epithelial to mesenchymal transition 0045666:positive regulation of neuron differentiation 0018108:peptidyl-tyrosine phosphorylation 0006468:protein phosphorylation 0007169:transmembrane receptor protein tyrosine kinase signaling pathway 0016477:cell migration 0031410:cytoplasmic vesicle 0043536:positive regulation of blood vessel endothelial cell migration 0007275:multicellular organism development 0005829:cytosol 2001239:regulation of extrinsic apoptotic signaling pathway in absence of ligand 0043009:chordate embryonic development 0042802:identical protein binding 0017134:fibroblast growth factor binding 0001764:neuron migration 0005576:extracellular region 0010863:positive regulation of phospholipase C activity 0046777:protein autophosphorylation 0001501:skeletal system development 2000546:positive regulation of endothelial cell chemotaxis to fibroblast growth factor 0005886:plasma membrane 0033674:positive regulation of kinase activity 0005887:integral component of plasma membrane 0045595:regulation of cell differentiation 0090722:receptor-receptor interaction 0010518:positive regulation of phospholipase activity 1905564:positive regulation of vascular endothelial cell proliferation 0043235:receptor complex 0042803:protein homodimerization activity 0048015:phosphatidylinositol-mediated signaling 0005634:nucleus 0008284:positive regulation of cell population proliferation 0008543:fibroblast growth factor receptor signaling pathway 0014068:positive regulation of phosphatidylinositol 3-kinase signaling 0005007:fibroblast growth factor-activated receptor activity 0051897:positive regulation of protein kinase B signaling 0043406:positive regulation of MAP kinase activity 0008201:heparin binding 0004714:transmembrane receptor protein tyrosine kinase activity
PDB	4NKA ; 5UQ0 ; 4RWL ; 5AM7 ; 1EVT ; 5A4C ; 6MZQ ; 6C1B ; 3GQL ; 4NK9 ; 6ITJ ; 4UWB ; 5W59 ; 3JS2 ; 5FLF ; 3KY2 ; 4UWY ; 2CR3 ; 1AGW ; 4ZSA ; 5A46 ; 6C1O ; 3GQI ; 4NKS ; 3KXX ; 4RWK ; 4V05 ; 6MZW ; 3KRL ; 4V01 ; 1FQ9 ; 4WUN ; 5VND ; 3DPK ; 6C1C ; 4F65 ; 3KRJ ; 3TT0 ; 3OJV ; 5O4A ; 4RWI ; 5EW8 ; 5UR1 ; 5ZV2 ; 6C19 ; 4F63 ; 5W21 ; 1FGK ; 6NVL ; 1CVS ; 2FGI ; 6P68 ; 1FGI ; 4V04 ; 5AM6 ; 4UWC ; 3RHX ; 3C4F ; 1XR0 ; 5B7V ; 4RWJ ; 5Z0S ; 6C18 ; 6P69 ; 4F64 ; 5O49
Drugbank	DB07525 ; DB15685 ; DB00039 ; DB12147 ; DB01109 ; DB05014 ; DB15102 ; DB07840 ; DB02058 ; DB08577 ; DB08901 ; DB08896 ; DB09078 ; DB12010 ; DB00398 ; DB09079 ; DB15822
KEGG	hsa:2260

Go to browser

Name: Epigalocatechin Gallate

Go to browser

Name: Calcitriol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0819	Zhi Zi Jin Gao	栀子浸膏	Cape jasmine fruit	Gardenia jasminoides
H1004	Bai Cha	白茶	White tea	Camellia sinensis
H0424	Shan Zhi	山栀	Cape jasmine	Gardenia jasminoides
H0189	Lv Cha	绿茶	Green tea	Folium camelliae sinensis
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0637	Cha Ye	茶叶	Common tea	Camellia sinensis
H1034	Fei Yang Cao	飞杨草	NA	Euphorbia hirta
H0721	Yang Mei Gen	杨梅根	Myrica rubra sieb. et zucc	Myrica rubra
H0166	Long Kui	龙葵	Black nightshade	Solanum nigrum
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H1029	Fang Er Cha	方儿茶	khair in hindi	Senegalia catechu
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0692	Xue Ren Shen	血人参	NA	Lespedeza bicolor