HIT-result

Type	Detail
Target ID	T06AO4
Protein Name	Membrane cofactor protein
Uniprot ID	P15529
Protein Name Alias	TLX; Trophoblast leukocyte common antigen; CD antigen CD46
Gene ID	4179
Gene Symbol	CD46
Gene Alias	MCP; MIC10
TTD	T21395: Clinical Trial target
Pfam	PF00084
GO	0038023:signaling receptor activity 0070062:extracellular exosome 0042102:positive regulation of T cell proliferation 0032733:positive regulation of interleukin-10 production 0005925:focal adhesion 0045591:positive regulation of regulatory T cell differentiation 0002250:adaptive immune response 0008593:regulation of Notch signaling pathway 0030449:regulation of complement activation 0007338:single fertilization 0005887:integral component of plasma membrane 0010628:positive regulation of gene expression 0005886:plasma membrane 0043382:positive regulation of memory T cell differentiation 0010629:negative regulation of gene expression 0006958:complement activation, classical pathway 0071636:positive regulation of transforming growth factor beta production 0009986:cell surface 0035581:sequestering of extracellular ligand from receptor 0002456:T cell mediated immunity 0002079:inner acrosomal membrane 0045296:cadherin binding 0001618:virus receptor activity 0045087:innate immune response
PDB	2O39 ; 1HR4 ; 3INB ; 5FO8 ; 1CKL ; 3O8E ; 3L89
Drugbank	NA
KEGG	hsa:4179

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description