Target Description

Type Detail
Target ID T37YKZ
Protein Name Endothelin receptor type B
Uniprot ID P24530
Protein Name Alias ET-B;  ET-BR;  Endothelin receptor non-selective type
Gene ID 1910
Gene Symbol EDNRB
Gene Alias ETRB
TTD T92828: Successful target
Pfam PF00001

0060406:positive regulation of penile erection

0017046:peptide hormone binding

0007497:posterior midgut development

0035810:positive regulation of urine volume

0051930:regulation of sensory perception of pain

0031620:regulation of fever generation

0019934:cGMP-mediated signaling

0007204:positive regulation of cytosolic calcium ion concentration

0007399:nervous system development

0042045:epithelial fluid transport

0071222:cellular response to lipopolysaccharide

0014070:response to organic cyclic compound

0008284:positive regulation of cell population proliferation

0006885:regulation of pH

0005887:integral component of plasma membrane

0007200:phospholipase C-activating G protein-coupled receptor signaling pathway



0030318:melanocyte differentiation

0007194:negative regulation of adenylate cyclase activity

0001934:positive regulation of protein phosphorylation

0005886:plasma membrane

0045121:membrane raft

0031965:nuclear membrane

0048484:enteric nervous system development

0007422:peripheral nervous system development

0043066:negative regulation of apoptotic process

0035645:enteric smooth muscle cell differentiation

0035815:positive regulation of renal sodium excretion

0048265:response to pain

1990839:response to endothelin

0048246:macrophage chemotaxis

0086100:endothelin receptor signaling pathway

0001755:neural crest cell migration

0000122:negative regulation of transcription by RNA polymerase II

0007186:G protein-coupled receptor signaling pathway

0019722:calcium-mediated signaling

0032269:negative regulation of cellular protein metabolic process

0050678:regulation of epithelial cell proliferation

0004962:endothelin receptor activity

0019233:sensory perception of pain

0008217:regulation of blood pressure

0007166:cell surface receptor signaling pathway

0014826:vein smooth muscle contraction

0031702:type 1 angiotensin receptor binding

0014043:negative regulation of neuron maturation

PDB 6LRY ; 5X93 ; 5XPR ; 6IGL ; 6IGK ; 5GLI ; 5GLH
Drugbank DB06460 ; DB06403 ; DB06138 ; DB00559 ; DB08932 ; DB06268 ; DB06558
KEGG hsa:1910

Related Compounds  (Total: 2)

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Name: Aldosterone
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Name: Calcitriol

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens