HIT-result

Type	Detail
Target ID	T37YKZ
Protein Name	Endothelin receptor type B
Uniprot ID	P24530
Protein Name Alias	ET-B; ET-BR; Endothelin receptor non-selective type
Gene ID	1910
Gene Symbol	EDNRB
Gene Alias	ETRB
TTD	T92828: Successful target
Pfam	PF00001
GO	0007568:aging 0060406:positive regulation of penile erection 0017046:peptide hormone binding 0007497:posterior midgut development 0035810:positive regulation of urine volume 0051930:regulation of sensory perception of pain 0031620:regulation of fever generation 0019934:cGMP-mediated signaling 0007204:positive regulation of cytosolic calcium ion concentration 0007399:nervous system development 0042045:epithelial fluid transport 0071222:cellular response to lipopolysaccharide 0014070:response to organic cyclic compound 0008284:positive regulation of cell population proliferation 0006885:regulation of pH 0005887:integral component of plasma membrane 0007200:phospholipase C-activating G protein-coupled receptor signaling pathway 0042310:vasoconstriction 0042311:vasodilation 0030318:melanocyte differentiation 0007194:negative regulation of adenylate cyclase activity 0001934:positive regulation of protein phosphorylation 0005886:plasma membrane 0045121:membrane raft 0031965:nuclear membrane 0048484:enteric nervous system development 0007422:peripheral nervous system development 0043066:negative regulation of apoptotic process 0035645:enteric smooth muscle cell differentiation 0035815:positive regulation of renal sodium excretion 0048265:response to pain 1990839:response to endothelin 0048246:macrophage chemotaxis 0086100:endothelin receptor signaling pathway 0001755:neural crest cell migration 0000122:negative regulation of transcription by RNA polymerase II 0007186:G protein-coupled receptor signaling pathway 0019722:calcium-mediated signaling 0032269:negative regulation of cellular protein metabolic process 0050678:regulation of epithelial cell proliferation 0004962:endothelin receptor activity 0019233:sensory perception of pain 0008217:regulation of blood pressure 0007166:cell surface receptor signaling pathway 0014826:vein smooth muscle contraction 0031702:type 1 angiotensin receptor binding 0014043:negative regulation of neuron maturation
PDB	6LRY ; 5X93 ; 5XPR ; 6IGL ; 6IGK ; 5GLI ; 5GLH
Drugbank	DB06460 ; DB06403 ; DB06138 ; DB00559 ; DB08932 ; DB06268 ; DB06558
KEGG	hsa:1910

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Name: Aldosterone

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Name: Calcitriol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens