Target Description

Type Detail
Target ID T75U40
Protein Name Cytotoxic T-lymphocyte protein 4
Uniprot ID P16410
Protein Name Alias Cytotoxic T-lymphocyte-associated antigen 4;  CTLA-4;  CD antigen CD152
Gene ID 1493
Gene Symbol CTLA4
Gene Alias CD152
TTD T15000: Successful target
Pfam PF07686
GO
0045590:negative regulation of regulatory T cell differentiation

0045334:clathrin-coated endocytic vesicle

0002250:adaptive immune response

0030889:negative regulation of B cell proliferation

0050852:T cell receptor signaling pathway

0031295:T cell costimulation

0006974:cellular response to DNA damage stimulus

0009897:external side of plasma membrane

0042130:negative regulation of T cell proliferation

0043065:positive regulation of apoptotic process

0050853:B cell receptor signaling pathway

0005794:Golgi apparatus

0005886:plasma membrane

0045589:regulation of regulatory T cell differentiation

0005887:integral component of plasma membrane

0006955:immune response

0050777:negative regulation of immune response

0048471:perinuclear region of cytoplasm

0098636:protein complex involved in cell adhesion

PDB 5XJ3 ; 5TRU ; 6XY2 ; 1I85 ; 1I8L ; 1AH1 ; 6RPJ ; 3OSK ; 6RQM ; 1H6E ; 5GGV ; 6RP8 ; 3BX7 ; 7CIO ; 2X44
Drugbank DB06186 ; DB11771
KEGG hsa:1493

Related Compounds  (Total: 2)

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C0739
Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione
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C1207
Name: Calcitriol


Related Herbs  (Total: 7)

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H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris