HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	1 Reference(s)
T90ZKN	Cathepsin B	CTSB	P07858	1 Reference(s)
T70OGQ	Sodium/potassium-transporting ATPase subunit alpha-1	ATP1A1	P05023	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	4 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	2 Reference(s)
T73EVE	Cyclic AMP-dependent transcription factor ATF-2	ATF2	P15336	1 Reference(s)
T75B9S	Cyclic AMP-responsive element-binding protein 1	CREB1	P16220	1 Reference(s)
T45G32	Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	1 Reference(s)
T34FQX	Protein kinase C zeta type	PRKCZ	Q05513	1 Reference(s)
T74QOR	Tyrosine-protein kinase JAK3	JAK3	P52333	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	3 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	2 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	3 Reference(s)
T57L0X	Oxysterols receptor LXR-alpha	NR1H3	Q13133	1 Reference(s)
T68XXK	4-aminobutyrate aminotransferase, mitochondrial	ABAT	P80404	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	3 Reference(s)
T57HGP	Tumor necrosis factor receptor superfamily member 6	FAS	P25445	2 Reference(s)
T32KN9	Alpha-amylase 1A	AMY1A	P0DUB6	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	5 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	5 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	6 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	16 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T24C0P	Bile acid receptor	NR1H4	Q96RI1	2 Reference(s)
T74P7I	G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	1 Reference(s)
T22NX4	Toll-like receptor 2	TLR2	O60603	3 Reference(s)
T76QBQ	CREB-regulated transcription coactivator 2	CRTC2	Q53ET0	1 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	3 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	2 Reference(s)
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	2 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	1 Reference(s)
T91T8I	Glucose-6-phosphatase catalytic subunit 1	G6PC1	P35575	1 Reference(s)
T37G49	Platelet-activating factor acetylhydrolase	PLA2G7	Q13093	1 Reference(s)
T14DX3	Ribosomal protein S6 kinase alpha-3	RPS6KA3	P51812	2 Reference(s)
T77TY2	Protein disulfide-isomerase	P4HB	P07237	2 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	2 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	7 Reference(s)
T83DDX	Endothelial protein C receptor	PROCR	Q9UNN8	1 Reference(s)
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	1 Reference(s)
T20RA0	Adenosine deaminase	ADA	P00813	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	2 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	3 Reference(s)
T25UYT	Dual specificity mitogen-activated protein kinase kinase 4	MAP2K4	P45985	1 Reference(s)
T39RV3	Dual specificity mitogen-activated protein kinase kinase 1	MAP2K1	Q02750	2 Reference(s)
T75IW3	Matrix metalloproteinase-14	MMP14	P50281	1 Reference(s)
T70KPE	Transient receptor potential cation channel subfamily V member 3	TRPV3	Q8NET8	1 Reference(s)
T09INZ	Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	4 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	7 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	3 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	2 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	3 Reference(s)
T24U57	E-selectin	SELE	P16581	1 Reference(s)
T72BXP	Platelet endothelial cell adhesion molecule	PECAM1	P16284	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	3 Reference(s)
T88QQE	Fibroblast growth factor 2	FGF2	P09038	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	11 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	4 Reference(s)
T39YUJ	Tyrosine-protein phosphatase non-receptor type 6	PTPN6	P29350	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	2 Reference(s)
T20H9F	Stromelysin-1	MMP3	P08254	1 Reference(s)
T95H9O	Stromelysin-2	MMP10	P09238	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	4 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	3 Reference(s)
T38OH4	Caspase-1	CASP1	P29466	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	2 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	3 Reference(s)
T11OU8	Progesterone receptor	PGR	P06401	1 Reference(s)
T16Q09	Bcl-2 homologous antagonist/killer	BAK1	Q16611	2 Reference(s)
T18MOS	Involucrin	IVL	P07476	1 Reference(s)
T98RXH	Focal adhesion kinase 1	PTK2	Q05397	1 Reference(s)
T40LTN	Phospholipase A2, membrane associated	PLA2G2A	P14555	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	2 Reference(s)
T76TED	Pro-opiomelanocortin	POMC	P01189	1 Reference(s)
T37JN5	Neutrophil gelatinase-associated lipocalin	LCN2	P80188	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	1 Reference(s)
T89L4V	Insulin	INS	P01308	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	1 Reference(s)
T16A2X	Catalase	CAT	P04040	2 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	2 Reference(s)
T80XW6	Scavenger receptor class B member 1	SCARB1	Q8WTV0	1 Reference(s)
T02DEN	Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide	GCG	P01275	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	3 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	3 Reference(s)
T77FOL	Neuromodulin	GAP43	P17677	1 Reference(s)
T00CXT	Prostaglandin G/H synthase 1	PTGS1	P23219	1 Reference(s)
T27U96	Granulocyte-macrophage colony-stimulating factor	CSF2	P04141	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	1 Reference(s)
T02GD4	Tumor necrosis factor ligand superfamily member 6	FASLG	P48023	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T22IMH	Cyclin-dependent kinase 6	CDK6	Q00534	1 Reference(s)
T38BR0	G1/S-specific cyclin-D2	CCND2	P30279	1 Reference(s)
T75H3W	Cyclin-dependent kinase 2	CDK2	P24941	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T64UH1	Nitric oxide synthase, endothelial	NOS3	P29474	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T04UTZ	G1/S-specific cyclin-E1	CCNE1	P24864	1 Reference(s)
T80OPZ	NADPH oxidase 4	NOX4	Q9NPH5	1 Reference(s)
T53ES3	Protein S100-A1	S100A1	P23297	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	1 Reference(s)
T04A6O	UDP-glucuronosyltransferase 1A3	UGT1A3	P35503	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	3 Reference(s)
T14LSK	E3 ubiquitin-protein ligase XIAP	XIAP	P98170	1 Reference(s)
T91OUC	Mucin-5AC	MUC5AC	P98088	1 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	1 Reference(s)
T64X48	C-X-C chemokine receptor type 4	CXCR4	P61073	1 Reference(s)
T61OY3	UDP-glucuronosyltransferase 1A1	UGT1A1	P22309	1 Reference(s)
T37WQE	Kallikrein-5	KLK5	Q9Y337	1 Reference(s)
T16DCZ	Twist-related protein 1	TWIST1	Q15672	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	2 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	1 Reference(s)
T18DUA	Tight junction protein ZO-1	TJP1	Q07157	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T51EKP	Apolipoprotein M	APOM	O95445	1 Reference(s)
T07VV7	Guanylin	GUCA2A	Q02747	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T80WPU	Protein ABHD15	ABHD15	Q6UXT9	1 Reference(s)
T56OUM	14-3-3 protein zeta/delta	YWHAZ	P63104	1 Reference(s)
T24YWQ	Insulin-degrading enzyme	IDE	P14735	1 Reference(s)
T34HYH	Interleukin-1 alpha	IL1A	P01583	1 Reference(s)
T60UPF	Parvalbumin alpha	PVALB	P20472	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T18CUI	Neuron-specific calcium-binding protein hippocalcin	HPCA	P84074	1 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T66S13	Dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	P36507	1 Reference(s)
T08SJX	Astrocytic phosphoprotein PEA-15	PEA15	Q15121	1 Reference(s)
T38OQ4	Peroxiredoxin-2	PRDX2	P32119	1 Reference(s)
T38J3Y	Gamma-enolase	ENO2	P09104	1 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T62ERY	Interleukin-1 receptor-associated kinase 4	IRAK4	Q9NWZ3	1 Reference(s)
T76AZQ	Histidine decarboxylase	HDC	P19113	1 Reference(s)
T98DNG	Natriuretic peptides A	NPPA	P01160	1 Reference(s)
T78ILO	Stearoyl-CoA desaturase	SCD	O00767	1 Reference(s)
T68IZC	Natriuretic peptides B	NPPB	P16860	1 Reference(s)
T02H9U	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	Q14934	1 Reference(s)
T87QUW	Actin, aortic smooth muscle	ACTA2	P62736	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T70HC9	Hepatocyte nuclear factor 1-alpha	HNF1A	P20823	1 Reference(s)
T49J7I	Hepatocyte nuclear factor 4-alpha	HNF4A	P41235	1 Reference(s)
T67RBZ	Mitochondrial uncoupling protein 2	UCP2	P55851	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	2 Reference(s)
T92E71	Corticosteroid 11-beta-dehydrogenase isozyme 2	HSD11B2	P80365	1 Reference(s)
T11GYO	Peroxisomal acyl-coenzyme A oxidase 1	ACOX1	Q15067	1 Reference(s)
T25H22	Protein kinase C beta type	PRKCB	P05771	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	1 Reference(s)

Herb ID: H0308	Chinese Character: 枇杷仁
English Name: NA	Latin Name: Eriobotrya japonica
Chinese Pin Yin : Pi Ba Ren	TCM-ID: TCMH1615
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: NA

Herb Description

Related Targets (Total: 158)

Related Compounds (Total: 18)