HIT-result

Type	Detail
Target ID	T11OU8
Protein Name	Progesterone receptor
Uniprot ID	P06401
Protein Name Alias	PR; Nuclear receptor subfamily 3 group C member 3
Gene ID	5241
Gene Symbol	PGR
Gene Alias	NR3C3
TTD	T22939: Successful target
Pfam	PF00105 ; PF02161 ; PF00104
GO	0001542:ovulation from ovarian follicle 0010629:negative regulation of gene expression 0060748:tertiary branching involved in mammary gland duct morphogenesis 0050847:progesterone receptor signaling pathway 0038001:paracrine signaling 0001225:RNA polymerase II transcription coactivator binding 0050678:regulation of epithelial cell proliferation 0005102:signaling receptor binding 0005829:cytosol 0004879:nuclear receptor activity 0042802:identical protein binding 0007267:cell-cell signaling 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0005654:nucleoplasm 0019899:enzyme binding 0051117:ATPase binding 0003677:DNA binding 0030518:intracellular steroid hormone receptor signaling pathway 0008270:zinc ion binding 0000785:chromatin 0005741:mitochondrial outer membrane 0045944:positive regulation of transcription by RNA polymerase II 0005496:steroid binding 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0003707:steroid hormone receptor activity 0002070:epithelial cell maturation 0006367:transcription initiation from RNA polymerase II promoter 0048286:lung alveolus development 0007165:signal transduction 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0006357:regulation of transcription by RNA polymerase II
PDB	4A2J ; 3D90 ; 3ZRB ; 1SQN ; 4APU ; 1A28 ; 1E3K ; 2OVM ; 3ZR7 ; 2OVH ; 5CC0 ; 1SR7 ; 3HQ5 ; 2W8Y ; 3ZRA ; 4OAR ; 2C7A ; 3KBA ; 3G8O ; 1ZUC
Drugbank	DB02746 ; DB00823 ; DB14512 ; DB00957 ; DB08906 ; DB02998 ; DB00764 ; DB00351 ; DB00396 ; DB05253 ; DB01431 ; DB00603 ; DB00431 ; DB00648 ; DB12941 ; DB00588 ; DB14583 ; DB11219 ; DB13867 ; DB00294 ; DB06730 ; DB13857 ; DB00378 ; DB01406 ; DB01428 ; DB06789 ; DB09123 ; DB06713 ; DB06680 ; DB04787 ; DB01395 ; DB11064 ; DB11619 ; DB08867 ; DB00367 ; DB00304 ; DB00834 ; DB09124 ; DB00421 ; DB00717 ; DB09389
KEGG	hsa:5241

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1055	Bai Guo Ren	白果仁	ginkgo	Ginkgo biloba
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0077	Jiu	酒	Ethanol	Vinum
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H1164	He Geng	荷梗	Hindu lotus petiole	Nelumbo nucifera
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0065	Jin Yin Hua Ti Qu Ye	金银花提取液	Japanese honeysuckle	Lonicera japonica
H0607	Wu Wei Zi Jin Chu Wu	五味子浸出物	Five-flavor berry	Schisandra chinensis
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0729	Ye Ju Hua	野菊花	Indian wild chrysanthemum flower	Chrysanthemum indicum
H0354	Ren Dong Teng	忍冬藤	Japanese honeysuckle vine	Lonicera japonica
H0370	Ru Xiang	乳香	Olibanum	Boswellia carterii
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0605	Wu Wei Zi	五味子	Chinese magnoliavine	Schisandra chinensis
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H0302	Ou Fen	藕粉	Hindu lotus large rhizome	Nelumbo nucifera
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0308	Pi Ba Ren	枇杷仁	NA	Eriobotrya japonica
H0606	Wu Wei Zi Chun Jin Gao	五味子醇浸膏	Five-flavor berry	Schisandra chinensis
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0141	Lian Zi Xin	莲子心	Hindu lotus plumule	Nelumbo nucifera
H0124	La Mei Hua	腊梅花	Wintersweet bud	Chimonanthus fragrans
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0064	Jin Yin Hua	金银花	Japanese honeysuckle	Lonicera japonica
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0750	Yin Xing Ye	银杏叶	Folium ginkgo	Ginkgo biloba
H0304	Ou Pian	藕片	Hindu lotus large rhizome	Nelumbo nucifera
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H1183	Hong Dou	红豆	Hosie ormosia	Ormosia hosiei
H0609	Wu Wei Zi Liu Jin Gao	五味子流浸膏	Five-flavor berry	Schisandra chinensis
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H0763	Yu Mi Xu	玉米须	Maize style	Zea mays
H0582	Cao Dou Kou Ren	草豆蔻仁	Katsumada galangal	Alpinia katsumadai
H0301	Ou	藕	Hindu lotus large rhizome	Nelumbo nucifera
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H1015	Du Zhong	杜仲	Eucommia	Eucommia ulmoides
H1017	Du Zhong Ye	杜仲叶	Eucommia leaf	Eucommia ulmoides
H1016	Du Zhong Tan	杜仲炭	Eucommia	Eucommia ulmoides
H0608	Wu Wei Zi Jin Gao	五味子浸膏	Five-flavor berry	Schisandra chinensis
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0416	Shan Shen	山参	NA	Panax ginseng
H0574	Cao Dou Kou	草豆蔻	Katsumada galangal	Alpinia katsumadai
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0604	Wu Wei Teng	五味藤	NA	Securidaca inappendiculata

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 62)