Compound Description
| ID: C1253 | Common name: Corosolic Acid |
| IUPAC: (1S,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid | CAS: CAS:4547-24-4 |
| Chembl ID: CHEMBL391533 | Pubchem ID: CID:6918774 |
| Formula: C30H48O4 | TCM-ID: TCMC943 |
| Smiles: C[C@@H]1CC[C@]2([C@@H]([C@H]1C)C1=CC[C@H]3[C@@]([C@@]1(CC2)C)(C)CC[C@@H]1[C@]3(C)C[C@@H](O)[C@@H](C1(C)C)O)C(=O)O | |
| Alias:
Urs-12-en-28-oic acid, 2α,3β-dihydroxy-;
(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid; 2alpha-Hydroxyursolic acid; 2α,2β,-Dihydroxy-12-en-28-ursolic acid; 2α,3β-Dihydroxy ursolic acid; 2α,3β-Dihydroxylursolic acid; 2α,3β-Dihydroxyurs-12-en-28-oic acid; 2α-Hydroxyursolic acid; Colosic acid; Colosolic acid; Corosolic acid; Corsolic acid; Glucosol |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
A | 1 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
B | 1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 31)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0638 | Xiang Bei | 象贝 | Fritillaria | Fritillaria thunbergii |
| H0230 | Mao Dong Qing | 毛冬青 | Pubescent holly | Ilex pubescens |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H0308 | Pi Ba Ren | 枇杷仁 | NA | Eriobotrya japonica |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0614 | Wu Zhao Long | 五爪龙 | Cairo morningglory | Ipomoea cairica |
| H0216 | Man Jing Ye | 蔓荆叶 | Threeleaf chastetree leaf | Vitex trifolia |
| H0217 | Man Jing Zi | 蔓荆子 | Threeleaf chastetree fruit | Vitex trifolia |
| H1203 | Hu Ji Sheng | 槲寄生 | Colored mistletoe | Viscum coloratum |
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H0656 | Xiao Bo Gen | 小檗根 | Barberry root | Berberis julianae |
| H0854 | Zi Wei Gen Pi | 紫葳根皮 | NA | Campsis grandiflora |
| H0327 | Qian Li Guang | 千里光 | Climbing groundsel | Senecio scandens |
| H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H0170 | Lu Bian Qing | 路边青 | Manyflower glorybower leaf | Clerodendron cyrtophyllum |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0370 | Ru Xiang | 乳香 | Olibanum | Boswellia carterii |
| H1229 | Bai Mu Xiang | 白木香 | Chinese eaglewood | Aquilaria sinensis |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H1117 | Guan Zhong | 贯众 | Male fern rhizome | Dryopteris crassirhizoma |
| H1056 | Fu Pen Zi | 覆盆子 | Red-and-Yellow garden raspberry | Rubus idaeus |
| H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
Ckey description of the interaction between compound and target