Herb Description
| Herb ID: H0158 | Chinese Character: 六棱菊 |
| English Name: NA | Latin Name: Laggera alata |
| Chinese Pin Yin : Liu Ling Ju | TCM-ID: TCMH1305 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 165)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
4 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
3 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
4 Reference(s) |
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
2 Reference(s) |
| T02O3F | Endothelial lipase | LIPG |
Q9Y5X9 |
1 Reference(s) |
| T11GYO | Peroxisomal acyl-coenzyme A oxidase 1 | ACOX1 |
Q15067 |
1 Reference(s) |
| T08UWG | NADPH oxidase 3 | NOX3 |
Q9HBY0 |
1 Reference(s) |
| T87UKX | Glucose-6-phosphate 1-dehydrogenase | G6PD |
P11413 |
1 Reference(s) |
| T92UBJ | Acetyl-CoA carboxylase 1 | ACACA |
Q13085 |
1 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
1 Reference(s) |
| T90ZKN | Cathepsin B | CTSB |
P07858 |
1 Reference(s) |
| T70OGQ | Sodium/potassium-transporting ATPase subunit alpha-1 | ATP1A1 |
P05023 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
2 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T73EVE | Cyclic AMP-dependent transcription factor ATF-2 | ATF2 |
P15336 |
1 Reference(s) |
| T75B9S | Cyclic AMP-responsive element-binding protein 1 | CREB1 |
P16220 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T34FQX | Protein kinase C zeta type | PRKCZ |
Q05513 |
1 Reference(s) |
| T74QOR | Tyrosine-protein kinase JAK3 | JAK3 |
P52333 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
| T57L0X | Oxysterols receptor LXR-alpha | NR1H3 |
Q13133 |
1 Reference(s) |
| T68XXK | 4-aminobutyrate aminotransferase, mitochondrial | ABAT |
P80404 |
1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
2 Reference(s) |
| T57HGP | Tumor necrosis factor receptor superfamily member 6 | FAS |
P25445 |
1 Reference(s) |
| T32KN9 | Alpha-amylase 1A | AMY1A |
P0DUB6 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
3 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
6 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
15 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
4 Reference(s) |
| T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
2 Reference(s) |
| T54VET | Protein tyrosine phosphatase type IVA 3 | PTP4A3 |
O75365 |
2 Reference(s) |
| T11ZYR | Cytochrome P450 2D6 | CYP2D6 |
P10635 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
5 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
2 Reference(s) |
| T37BP1 | Serine/threonine-protein kinase pim-1 | PIM1 |
P11309 |
1 Reference(s) |
| T20VPX | Cyclin-dependent-like kinase 5 | CDK5 |
Q00535 |
1 Reference(s) |
| T00RT4 | Inosine-5'-monophosphate dehydrogenase 1 | IMPDH1 |
P20839 |
1 Reference(s) |
| T68B5V | Inosine-5'-monophosphate dehydrogenase 2 | IMPDH2 |
P12268 |
1 Reference(s) |
| T78C6N | Cathepsin K | CTSK |
P43235 |
1 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
1 Reference(s) |
| T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
1 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
2 Reference(s) |
| T77TY2 | Protein disulfide-isomerase | P4HB |
P07237 |
1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
| T41B8C | Peroxiredoxin-5, mitochondrial | PRDX5 |
P30044 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
9 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
3 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
2 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
1 Reference(s) |
| T45XTW | Retinoic acid receptor RXR-alpha | RXRA |
P19793 |
1 Reference(s) |
| T41A4Y | Lamin-B1 | LMNB1 |
P20700 |
1 Reference(s) |
| T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
| T16MRJ | Trifunctional enzyme subunit beta, mitochondrial | HADHB |
P55084 |
1 Reference(s) |
| T20HY9 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial | DECR1 |
Q16698 |
1 Reference(s) |
| T43FA8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | ACADM |
P11310 |
1 Reference(s) |
| T60LKM | Peroxisomal bifunctional enzyme | EHHADH |
Q08426 |
1 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
2 Reference(s) |
| T90ZS8 | Endothelin-converting enzyme 1 | ECE1 |
P42892 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
2 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
| T14W2H | ATP-citrate synthase | ACLY |
P53396 |
1 Reference(s) |
| T69DAO | Enoyl-CoA delta isomerase 1, mitochondrial | ECI1 |
P42126 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
4 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
7 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
3 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
6 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
1 Reference(s) |
| T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 |
P16284 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
3 Reference(s) |
| T88QQE | Fibroblast growth factor 2 | FGF2 |
P09038 |
1 Reference(s) |
| T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
4 Reference(s) |
| T39YUJ | Tyrosine-protein phosphatase non-receptor type 6 | PTPN6 |
P29350 |
1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
2 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T95H9O | Stromelysin-2 | MMP10 |
P09238 |
2 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
6 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
4 Reference(s) |
| T38OH4 | Caspase-1 | CASP1 |
P29466 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
2 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
1 Reference(s) |
| T48TW0 | Platelet glycoprotein 4 | CD36 |
P16671 |
1 Reference(s) |
| T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
1 Reference(s) |
| T99XQ3 | DNA topoisomerase 1 | TOP1 |
P11387 |
1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
| T36NQ9 | Mothers against decapentaplegic homolog 1 | SMAD1 |
Q15797 |
2 Reference(s) |
| T22J9V | Tyrosine-protein kinase JAK1 | JAK1 |
P23458 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
3 Reference(s) |
| T68CKY | Tyrosine-protein kinase Fyn | FYN |
P06241 |
1 Reference(s) |
| T37WY2 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | PCK1 |
P35558 |
1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
2 Reference(s) |
| T68AKE | Zinc fingers and homeoboxes protein 2 | ZHX2 |
Q9Y6X8 |
1 Reference(s) |
| T14DX3 | Ribosomal protein S6 kinase alpha-3 | RPS6KA3 |
P51812 |
1 Reference(s) |
| T18CWB | Transcriptional activator Myb | MYB |
P10242 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T83TMF | Cytochrome P450 2B1 | Cyp2b1 |
P00176 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
1 Reference(s) |
| T80PUR | Caspase-7 | CASP7 |
P55210 |
1 Reference(s) |
| T23EWB | Transcriptional repressor protein YY1 | YY1 |
P25490 |
1 Reference(s) |
| T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
P04626 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
2 Reference(s) |
| T44KU9 | Cytochrome P450 2B6 | CYP2B6 |
P20813 |
1 Reference(s) |
| T61OY3 | UDP-glucuronosyltransferase 1A1 | UGT1A1 |
P22309 |
2 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T20TB8 | NADPH oxidase 1 | NOX1 |
Q9Y5S8 |
1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
1 Reference(s) |
| T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B |
O00300 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
2 Reference(s) |
| T03G09 | Tumor necrosis factor ligand superfamily member 11 | TNFSF11 |
O14788 |
1 Reference(s) |
| T77FOL | Neuromodulin | GAP43 |
P17677 |
1 Reference(s) |
| T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
1 Reference(s) |
| T22IMH | Cyclin-dependent kinase 6 | CDK6 |
Q00534 |
1 Reference(s) |
| T38BR0 | G1/S-specific cyclin-D2 | CCND2 |
P30279 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
| T75HMM | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 |
Q07820 |
1 Reference(s) |
| T04UTZ | G1/S-specific cyclin-E1 | CCNE1 |
P24864 |
1 Reference(s) |
| T80OPZ | NADPH oxidase 4 | NOX4 |
Q9NPH5 |
1 Reference(s) |
| T53ES3 | Protein S100-A1 | S100A1 |
P23297 |
1 Reference(s) |
| T04A6O | UDP-glucuronosyltransferase 1A3 | UGT1A3 |
P35503 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
3 Reference(s) |
| T14LSK | E3 ubiquitin-protein ligase XIAP | XIAP |
P98170 |
1 Reference(s) |
| T91OUC | Mucin-5AC | MUC5AC |
P98088 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
| T64X48 | C-X-C chemokine receptor type 4 | CXCR4 |
P61073 |
1 Reference(s) |
| T37WQE | Kallikrein-5 | KLK5 |
Q9Y337 |
1 Reference(s) |
| T16DCZ | Twist-related protein 1 | TWIST1 |
Q15672 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T02JCT | Protein AATF | AATF |
Q9NY61 |
1 Reference(s) |
| T08J6P | NA | MIR146B |
NA |
1 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
1 Reference(s) |
| T90ORW | Bcl2-associated agonist of cell death | BAD |
Q92934 |
1 Reference(s) |
| T60UPF | Parvalbumin alpha | PVALB |
P20472 |
2 Reference(s) |
| T18CUI | Neuron-specific calcium-binding protein hippocalcin | HPCA |
P84074 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T66S13 | Dual specificity mitogen-activated protein kinase kinase 2 | MAP2K2 |
P36507 |
1 Reference(s) |
| T08SJX | Astrocytic phosphoprotein PEA-15 | PEA15 |
Q15121 |
1 Reference(s) |
| T38OQ4 | Peroxiredoxin-2 | PRDX2 |
P32119 |
1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
1 Reference(s) |
| T34X07 | CCAAT/enhancer-binding protein alpha | CEBPA |
P49715 |
1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
1 Reference(s) |
| T18YXD | Albumin | ALB |
P02768 |
1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
1 Reference(s) |
| T63YAO | Caveolin-1 | CAV1 |
Q03135 |
1 Reference(s) |
Related Compounds (Total: 11)
C0935
Name: Astragalin
C1180
Name: Betulinic Acid
C0291
Name: Paraben
C0399
Name: Sesamin
C0476
Name: Ursolic Acid
key description of the interaction between compound and target