Target Description

Type Detail
Target ID T90ZS8
Protein Name Endothelin-converting enzyme 1
Uniprot ID P42892
Protein Name Alias ECE-1;  EC 3.4.24.71
Gene ID 1889
Gene Symbol ECE1
Gene Alias NA
TTD T50970: Research target
Pfam PF01431 ; PF05649
GO
0070062:extracellular exosome

0031982:vesicle

0033093:Weibel-Palade body

0016021:integral component of membrane

0010814:substance P catabolic process

0010815:bradykinin catabolic process

0016020:membrane

0043583:ear development

0007507:heart development

0042447:hormone catabolic process

0004222:metalloendopeptidase activity

0007186:G protein-coupled receptor signaling pathway

0017046:peptide hormone binding

0034959:endothelin maturation

0009897:external side of plasma membrane

0016485:protein processing

0005886:plasma membrane

0005765:lysosomal membrane

0005769:early endosome

0005768:endosome

0019229:regulation of vasoconstriction

0003100:regulation of systemic arterial blood pressure by endothelin

0048471:perinuclear region of cytoplasm

0008270:zinc ion binding

0001921:positive regulation of receptor recycling

0042803:protein homodimerization activity

0004175:endopeptidase activity

0016486:peptide hormone processing

0031302:intrinsic component of endosome membrane

0042733:embryonic digit morphogenesis

0010816:calcitonin catabolic process

PDB 3DWB
Drugbank DB07171
KEGG hsa:1889

Related Compounds  (Total: 4)

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C0305
Name: Phorbol Myristate Acetate
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C0399
Name: Sesamin
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C0428
Name: Tanshinone Iia
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C1278
Name: Daidzein


Related Herbs  (Total: 89)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0096 Ju San Qi菊三七 NAGynura japonica
H0019 Ji Xue Teng Gao鸡血藤膏 Suberect spatholobus stemSpatholobus suberectus
H0295 Bi Ba荜茇 Long pepperPiper longum
H0981 Dian Ji Xue Teng Gao Fen滇鸡血藤膏粉 Suberect spatholobus stemSpatholobus suberectus
H0918 Cu Yuan Hua醋芫花 Lilac daphneDaphne genkwa
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0897 Chuan Lian川楝 ChinaberryMelia azedarach
H0705 Yan Hu Lu Ba盐胡芦巴 FenugreekTrigonella foenum-graecum
H0789 Zhang Shu Gen樟树根 Camphor treeCinnamomum camphora
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0707 Yuan Hua芫花 Lilac daphneDaphne genkwa
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0787 Zhang Nao樟脑 CamphorarCinnamomum camphora
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H0277 Nan Ban Lan Gen南板蓝根 Indigowoad rootBaphicacanthus cusia
H1021 E Da Xia莪大夏 NAOxytropis falcata
H0708 Yuan Hua Gen芫花根 Lilac daphne rootDaphne genkwa
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0461 Shi Jun Zi Ren使君子仁 NACombretum indicum
H0629 Xi Xin细辛 Siebold wildgingerAsarum sieboldii
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0026 Jiang Soybean pasteGlycine max
H0710 Yuan Hua Tiao芫花条 stem of lilac daphneDaphne genkwa
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0405 Shan Dou Gen山豆根 Tonkin sophora rootSophora subprostrata
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H1086 Bai Hua Cai Zi白花菜子 Common spiderflower seedCleome gynandra
H0580 Tu Si Rou菟丝肉 Dodder seedCuscuta australis
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1007 Dou You豆油 Soybean oilGlycine max
H0024 Jia 蒟ye假蒟叶 Sarmentose pepperPiper sarmentosum
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0018 Ji Xue Teng Gan Gao鸡血藤干膏 Suberect spatholobus stemSpatholobus suberectus
H0711 Yuan Hua Zhi Tiao芫花枝条 stem of lilac daphneDaphne genkwa
H1248 Huang Qi Gan Jin Gao黄芪干浸膏 Membranous milkvetchAstragalus membranaceus
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0788 Zhang Nao Zi樟脑子 CamphorarCinnamomum camphora
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0278 Nan Ban Lan Gen Jin Gao Fen南板蓝根浸膏粉 Indigowoad rootBaphicacanthus cusia
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0583 Tu Si Zi Teng菟丝子藤 Dodder seedCuscuta australis
H0848 Zi Jin Niu紫金牛 Japanese ardisiaArdisia japonica
H0967 Di Er Cao地耳草 Japanese stJohn’swortHypericum japonicum
H0323 Qian Hu前胡 Common hogfennelAngelica decursiva
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0098 Ju Ye San Qi菊叶三七 NAGynura japonica
H1247 Huang Qi黄芪 Membranous milkvetchAstragalus membranaceus
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0022 Jia Ju假蒟 Sarmentose pepperPiper sarmentosum
H0786 Zhang Mu樟木 Ligum cinmamomi camphoraeCinnamomum camphora
H0233 Mao Liang Mian Zhen毛两面针 NAZanthoxylum nitidum
H0158 Liu Ling Ju六棱菊 NALaggera alata
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0790 Zhang Shu Zi樟树子 Camphor treeCinnamomum camphora
H0581 Tu Si Zi菟丝子 Dodder seedCuscuta australis
H1250 Huang Qi Ti Qu Ye黄芪提取液 Membranous milkvetchAstragalus membranaceus
H0017 Ji Xue Teng鸡血藤 Suberect spatholobus stemSpatholobus suberectus
H1167 He Tao核桃 English walnut seedSemen juglandis
H1249 Huang Qi Jin Gao黄芪浸膏 Membranous milkvetchAstragalus membranaceus
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium