HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T88LSZ	Aromatase	CYP19A1	P11511	2 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	7 Reference(s)
T57L0X	Oxysterols receptor LXR-alpha	NR1H3	Q13133	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	3 Reference(s)
T31U13	Cytochrome P450 2C19	CYP2C19	P33261	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	6 Reference(s)
T82G3R	Integrin beta-3	ITGB3	P05106	1 Reference(s)
T78O6C	Mothers against decapentaplegic homolog 3	SMAD3	P84022	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	4 Reference(s)
T24C0P	Bile acid receptor	NR1H4	Q96RI1	1 Reference(s)
T16MRU	NACHT, LRR and PYD domains-containing protein 3	NLRP3	Q96P20	2 Reference(s)
T13HKH	Integrin alpha-5	ITGA5	P08648	1 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	2 Reference(s)
T86CQC	Glutamate receptor ionotropic, NMDA 1	GRIN1	Q05586	1 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	8 Reference(s)
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	1 Reference(s)
T82ALJ	Glycogen synthase kinase-3 beta	GSK3B	P49841	1 Reference(s)
T00CXT	Prostaglandin G/H synthase 1	PTGS1	P23219	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	3 Reference(s)
T08DOL	Sulfotransferase 1E1	SULT1E1	P49888	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	1 Reference(s)
T61J7T	Mothers against decapentaplegic homolog 2	SMAD2	Q15796	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	3 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	4 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	1 Reference(s)
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	1 Reference(s)
T54G8J	Protein kinase C delta type	PRKCD	Q05655	2 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	3 Reference(s)
T20IHC	Diacylglycerol O-acyltransferase 1	DGAT1	O75907	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	1 Reference(s)
T16UZ4	Dipeptidyl peptidase 4	DPP4	P27487	1 Reference(s)
T66NVP	Fatty-acid amide hydrolase 1	FAAH	O00519	1 Reference(s)
T45I46	Mitogen-activated protein kinase kinase kinase 11	MAP3K11	Q16584	2 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	2 Reference(s)
T03VS9	Protein-tyrosine kinase 2-beta	PTK2B	Q14289	2 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	4 Reference(s)
T91W8B	All-trans-retinol dehydrogenase [NAD(+)] ADH4	ADH4	P08319	1 Reference(s)
T44WZO	Alcohol dehydrogenase 1C	ADH1C	P00326	1 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	1 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	1 Reference(s)
T63YAO	Caveolin-1	CAV1	Q03135	3 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	6 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T32OC4	Aldehyde dehydrogenase, mitochondrial	ALDH2	P05091	1 Reference(s)
T22MME	Quinone oxidoreductase	CRYZ	Q08257	1 Reference(s)
T05O6O	Estrogen receptor beta	ESR2	Q92731	8 Reference(s)
T22JG3	Fibroblast growth factor receptor 2	FGFR2	P21802	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	2 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T48J1U	Aldo-keto reductase family 1 member C1	AKR1C1	Q04828	1 Reference(s)
T21EGX	Multidrug resistance-associated protein 1	ABCC1	P33527	1 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	1 Reference(s)
T45XTW	Retinoic acid receptor RXR-alpha	RXRA	P19793	1 Reference(s)
T54SZZ	Endoplasmic reticulum chaperone BiP	HSPA5	P11021	1 Reference(s)
T20MBF	Serotransferrin	TF	P02787	1 Reference(s)
T36YWU	Kelch-like ECH-associated protein 1	KEAP1	Q14145	1 Reference(s)
T76B0A	Gap junction alpha-1 protein	GJA1	P17302	2 Reference(s)
T93YV8	Tumor necrosis factor receptor superfamily member 11B	TNFRSF11B	O00300	1 Reference(s)
T02GD4	Tumor necrosis factor ligand superfamily member 6	FASLG	P48023	2 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	3 Reference(s)
T97KL5	Microsomal glutathione S-transferase 1	MGST1	P10620	2 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	4 Reference(s)
T81BH5	Sulfotransferase 1A1	SULT1A1	P50225	2 Reference(s)
T32SPJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	P48736	1 Reference(s)
T04AHN	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	HSD3B2	P26439	1 Reference(s)
T23K1O	Calmodulin	CALM3;CALML2;CAM3;CAMC;CAMIII	P62158	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	3 Reference(s)
T09TS5	Gamma-aminobutyric acid type B receptor subunit 1	GABBR1	Q9UBS5	1 Reference(s)
T74ETU	Steroid 21-hydroxylase	CYP21A2	P08686	1 Reference(s)
T50WUM	Leucine--tRNA ligase, cytoplasmic	LARS1	Q9P2J5	1 Reference(s)
T30V3R	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	HSD3B1	P14060	2 Reference(s)
T67HAF	Signal transducer and activator of transcription 1-alpha/beta	STAT1	P42224	1 Reference(s)
T29GH0	Trefoil factor 1	TFF1	P04155	2 Reference(s)
T98JPP	Carnitine O-palmitoyltransferase 1, liver isoform	CPT1A	P50416	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	3 Reference(s)
T50V79	Interleukin-4	IL4	P05112	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	3 Reference(s)
T64UH1	Nitric oxide synthase, endothelial	NOS3	P29474	1 Reference(s)
T73S71	Apolipoprotein B-100	APOB	P04114	2 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	3 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	1 Reference(s)
T95VJ9	Thiamine transporter 2	SLC19A3	Q9BZV2	1 Reference(s)
T16A2X	Catalase	CAT	P04040	4 Reference(s)
T30D9G	Superoxide dismutase [Cu-Zn]	SOD1	P00441	2 Reference(s)
T23RXU	Glutathione reductase, mitochondrial	GSR	P00390	1 Reference(s)
T46AQJ	Glutathione S-transferase P	GSTP1	P09211	1 Reference(s)
T59DDI	Liver carboxylesterase 1	CES1	P23141	1 Reference(s)
T03NWF	Sterol O-acyltransferase 1	SOAT1	P35610	1 Reference(s)
T95RKQ	Sterol O-acyltransferase 2	SOAT2	O75908	1 Reference(s)
T35FQV	Microsomal triglyceride transfer protein large subunit	MTTP	P55157	2 Reference(s)
T30TYH	Phospholipase A2	PLA2G1B	P04054	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T95H9O	Stromelysin-2	MMP10	P09238	1 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	1 Reference(s)
T83TMF	Cytochrome P450 2B1	Cyp2b1	P00176	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	2 Reference(s)
T17CZC	Tissue factor	F3	P13726	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T80PUR	Caspase-7	CASP7	P55210	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	2 Reference(s)
T71B0A	Cytosolic phospholipase A2	PLA2G4A	P47712	1 Reference(s)
T53KY7	Cystic fibrosis transmembrane conductance regulator	CFTR	P13569	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	2 Reference(s)
T04HTN	Cyclic AMP-dependent transcription factor ATF-3	ATF3	P18847	2 Reference(s)
T05XOE	Macrophage mannose receptor 1	MRC1	P22897	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T34X07	CCAAT/enhancer-binding protein alpha	CEBPA	P49715	2 Reference(s)
T51RTI	NA	HOTAIR	NA	1 Reference(s)
T08KXM	Low-density lipoprotein receptor-related protein 5	LRP5	O75197	1 Reference(s)
T05AAL	Microphthalmia-associated transcription factor	MITF	O75030	1 Reference(s)
T72KIO	Peroxiredoxin-1	PRDX1	Q06830	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	2 Reference(s)
T87O4D	Mitogen-activated protein kinase 7	MAPK7	Q13164	1 Reference(s)
T04LY5	Creatine kinase B-type	CKB	P12277	1 Reference(s)
T67JR8	Heat shock factor protein 1	HSF1	Q00613	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	3 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T40G6B	Prostaglandin reductase 1	PTGR1	Q14914	3 Reference(s)
T08B2M	M-phase inducer phosphatase 1	CDC25A	P30304	1 Reference(s)
T33UEM	Lactoperoxidase	LPO	P22079	1 Reference(s)
T03TJ0	Interleukin-33	IL33	O95760	1 Reference(s)
T31VDH	Myeloid differentiation primary response protein MyD88	MYD88	Q99836	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	2 Reference(s)
T46K2X	Heat shock 70 kDa protein 4	HSPA4	P34932	1 Reference(s)
T46J84	Nicotinamide phosphoribosyltransferase	NAMPT	P43490	1 Reference(s)
T91RI2	Endophilin-A2	SH3GL1	Q99961	1 Reference(s)
T23RWU	Type-1 angiotensin II receptor	AGTR1	P30556	1 Reference(s)
T47MPW	T-lymphocyte activation antigen CD86	CD86	P42081	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	2 Reference(s)
T26UZV	Dual specificity mitogen-activated protein kinase kinase 5	MAP2K5	Q13163	1 Reference(s)
T58D39	Osteocalcin	BGLAP	P02818	1 Reference(s)
T07NZK	Low affinity immunoglobulin epsilon Fc receptor	FCER2	P06734	1 Reference(s)
T11GHO	Transforming protein RhoA	RHOA	P61586	1 Reference(s)
T34AYH	Solute carrier family 52, riboflavin transporter, member 1	SLC52A1	Q9NWF4	1 Reference(s)
T36I66	Metallothionein-2	MT2A	P02795	1 Reference(s)
T90ZS8	Endothelin-converting enzyme 1	ECE1	P42892	1 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	1 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	1 Reference(s)
T42XY2	Insulin-like growth factor 1 receptor	IGF1R	P08069	1 Reference(s)
T16IWB	Growth arrest and DNA damage-inducible protein GADD45 alpha	GADD45A	P24522	1 Reference(s)
T29CYD	BRCA1-associated RING domain protein 1	BARD1	Q99728	1 Reference(s)
T41SFE	Histone acetyltransferase p300	EP300	Q09472	1 Reference(s)
T57R3V	Proliferation marker protein Ki-67	MKI67	P46013	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T82I76	Ubiquitin carboxyl-terminal hydrolase BAP1	BAP1	Q92560	1 Reference(s)
T82S9G	DNA repair protein RAD51 homolog 1	RAD51	Q06609	1 Reference(s)
T53QOD	ATP synthase subunit beta, mitochondrial	ATP5F1B	P06576	1 Reference(s)
T63SUZ	NADH-ubiquinone oxidoreductase chain 6	MT-ND6	P03923	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	1 Reference(s)
T46HRF	Growth hormone receptor	GHR	P10912	1 Reference(s)
T70SFS	Superoxide dismutase [Mn], mitochondrial	SOD2	P04179	1 Reference(s)
T28B0B	Monocarboxylate transporter 8	SLC16A2	P36021	1 Reference(s)
T53GFX	Arginase-1	ARG1	P05089	1 Reference(s)
T35QZO	Cytochrome c	CYCS	P99999	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T90XMB	Ubiquitin carboxyl-terminal hydrolase 5	USP5	P45974	1 Reference(s)
T33KFW	Matrilysin	MMP7	P09237	1 Reference(s)
T47YS7	Transketolase	TKT	P29401	1 Reference(s)
T75B9S	Cyclic AMP-responsive element-binding protein 1	CREB1	P16220	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	2 Reference(s)
T90ORW	Bcl2-associated agonist of cell death	BAD	Q92934	1 Reference(s)
T33OSQ	Sterol regulatory element-binding protein 1	SREBF1	P36956	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	1 Reference(s)
T95IYZ	Adiponectin	ADIPOQ	Q15848	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	1 Reference(s)
T84XYQ	Polycystin-2	PKD2	Q13563	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	1 Reference(s)
T26EZU	Myc proto-oncogene protein	MYC	P01106	1 Reference(s)
T18YXD	Albumin	ALB	P02768	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)

Herb ID: H0705	Chinese Character: 盐胡芦巴
English Name: Fenugreek	Latin Name: Trigonella foenum-graecum
Chinese Pin Yin : Yan Hu Lu Ba	TCM-ID: TCMH2375
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: NA

Herb Description

Related Targets (Total: 173)

Related Compounds (Total: 16)