Target Description

Type Detail
Target ID T04HTN
Protein Name Cyclic AMP-dependent transcription factor ATF-3
Uniprot ID P18847
Protein Name Alias cAMP-dependent transcription factor ATF-3;  Activating transcription factor 3
Gene ID 467
Gene Symbol ATF3
Gene Alias NA
TTD T11966: Research target
Pfam PF00170
GO
0042802:identical protein binding

0005634:nucleus

0061394:regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

0008284:positive regulation of cell population proliferation

0035914:skeletal muscle cell differentiation

1990622:CHOP-ATF3 complex

0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding

0010999:regulation of eIF2 alpha phosphorylation by heme

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0034198:cellular response to amino acid starvation

0000785:chromatin

0000976:transcription regulatory region sequence-specific DNA binding

1990440:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

0005730:nucleolus

1903984:positive regulation of TRAIL-activated apoptotic signaling pathway

0030968:endoplasmic reticulum unfolded protein response

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0000122:negative regulation of transcription by RNA polymerase II

0003700:DNA-binding transcription factor activity

0042803:protein homodimerization activity

0006357:regulation of transcription by RNA polymerase II

0046982:protein heterodimerization activity

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

1990837:sequence-specific double-stranded DNA binding

0006094:gluconeogenesis

0045944:positive regulation of transcription by RNA polymerase II

0070373:negative regulation of ERK1 and ERK2 cascade

PDB NA
Drugbank DB00852
KEGG hsa:467

Related Compounds  (Total: 2)

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C0242
Name: Naringenin
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C1188
Name: Biochanin


Related Herbs  (Total: 74)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0198 Ma Huang Gao麻黄膏 Chinese ephedraEphedra sinica
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0826 Chu Mu Dan臭牡丹 rose glorybowerClerodendrum bungei
H0957 Dang Gui Teng当归藤 NAEmbelia parviflora
H0201 Ma Huang Jin Gao麻黄浸膏 Chinese ephedraEphedra sinica
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0805 Zhi Ke Gan Jin Gao枳壳干浸膏 Seville ora nge unripe fruitCitrus aurantium
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0663 Xiao Ji小蓟 Setose thistleCirsium setosum
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0089 Ju Hong橘红 NACitri exocarpium rubrum
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H1247 Huang Qi黄芪 Membranous milkvetchAstragalus membranaceus
H1133 Gui Jian Yu鬼箭羽 Winged euonymusEuonymus alatus
H0802 Zhi Geng枳梗 NACitrus aurantium
H0629 Xi Xin细辛 Siebold wildgingerAsarum sieboldii
H1250 Huang Qi Ti Qu Ye黄芪提取液 Membranous milkvetchAstragalus membranaceus
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0166 Long Kui龙葵 Black nightshadeSolanum nigrum
H0758 Cheng Pi橙皮 Bitter orangeCitrus aurantium
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0246 Mi Ma Huang蜜麻黄 Ephedra equisetinEphedra sinica
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H1225 Huai Mi槐米 NASophora japonica
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0813 Zhi Shi枳实 Seville orange young fruitCitrus aurantium
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0278 Nan Ban Lan Gen Jin Gao Fen南板蓝根浸膏粉 Indigowoad rootBaphicacanthus cusia
H0164 Ban Zhi Lian半枝莲 Barbed skullcapScutellaria barbata
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H0601 Wu Mei乌梅 Japanese apricotPrunus mume
H1227 Huai Zhi槐枝 NASophora japonica
H0602 Wu Mei Rou乌梅肉 EbonyPrunus mume
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1248 Huang Qi Gan Jin Gao黄芪干浸膏 Membranous milkvetchAstragalus membranaceus
H0705 Yan Hu Lu Ba盐胡芦巴 FenugreekTrigonella foenum-graecum
H1141 Guo Gang Long Jin Gao过岗龙浸膏 NAEntada phaseoloides
H1034 Fei Yang Cao飞杨草 NAEuphorbia hirta
H0965 Deng Zhan Xi Xin灯盏细辛 Shortscape fleabaneErigeron breviscapus
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H1217 Bai Mei Hua白梅花 Japanese apricot flowerPrunus mume
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H0200 Ma Huang Gen麻黄根 Chinese ephedra rootEphedra sinica
H0457 Shi Er石耳 Rock-EarsUmbilicaria esculenta
H1249 Huang Qi Jin Gao黄芪浸膏 Membranous milkvetchAstragalus membranaceus
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0555 Tie Xian Cai铁苋菜 Copperleaf herbHerba acalyphae
H1140 Guo Gang Long过岗龙 NAEntada phaseoloides
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H1161 Hang Ju杭菊 Chrysanthemum flowerChrysanthemum morifolium
H0369 Bian Fu Ge蝙蝠葛 Asiatic moonseedMenispermum dauricum
H0804 Zhi Ke枳壳 Seville ora nge unripe fruitCitrus aurantium
H0277 Nan Ban Lan Gen南板蓝根 Indigowoad rootBaphicacanthus cusia
H1098 Gou Ji狗脊 Cochinchina cudraniaCudrania cochinchinensis
H0197 Ma Huang麻黄 Chinese ephedraEphedra sinica
H0092 Ju Hua菊花 Florists chrysanthemum flowerChrysanthemum morifolium