Compound Description
| ID: C1188 | Common name: Biochanin |
| IUPAC: 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one | CAS: CAS:491-80-5 |
| Chembl ID: CHEMBL131921 | Pubchem ID: CID:5280373 |
| Formula: C16H12O5 | TCM-ID: TCMC811 |
| Smiles: COc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O | |
| Alias:
Biochanin A;
Isoflavone, 5,7-dihydroxy-4'-methoxy-; 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one; (-)-5,7-Dihydroxy-4'-methoxyisoflavone; 4'-Methylgenistein; 5,7-Dihydroxy-4'-methoxyisoflavone; Biochanin; Genistein 4-methyl ether; Genistein 4'-methyl ether; NSC 123538; Olmelin |
Structure:
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Related Targets (Total: 14)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T66NVP | Fatty-acid amide hydrolase 1 | FAAH |
O00519 |
A | 1 Reference(s) |
| T45I46 | Mitogen-activated protein kinase kinase kinase 11 | MAP3K11 |
Q16584 |
A | 2 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
A | 1 Reference(s) |
| T03VS9 | Protein-tyrosine kinase 2-beta | PTK2B |
Q14289 |
A | 1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
A | 1 Reference(s) |
| T46K2X | Heat shock 70 kDa protein 4 | HSPA4 |
P34932 |
C | 1 Reference(s) |
| T46J84 | Nicotinamide phosphoribosyltransferase | NAMPT |
P43490 |
C | 1 Reference(s) |
| T91RI2 | Endophilin-A2 | SH3GL1 |
Q99961 |
C | 1 Reference(s) |
| T23RWU | Type-1 angiotensin II receptor | AGTR1 |
P30556 |
C | 1 Reference(s) |
| T47MPW | T-lymphocyte activation antigen CD86 | CD86 |
P42081 |
C | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
C | 1 Reference(s) |
| T26UZV | Dual specificity mitogen-activated protein kinase kinase 5 | MAP2K5 |
Q13163 |
C | 1 Reference(s) |
| T58D39 | Osteocalcin | BGLAP |
P02818 |
C | 1 Reference(s) |
| T04HTN | Cyclic AMP-dependent transcription factor ATF-3 | ATF3 |
P18847 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 24)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0246 | Mi Ma Huang | 蜜麻黄 | Ephedra equisetin | Ephedra sinica |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0198 | Ma Huang Gao | 麻黄膏 | Chinese ephedra | Ephedra sinica |
| H1247 | Huang Qi | 黄芪 | Membranous milkvetch | Astragalus membranaceus |
| H0197 | Ma Huang | 麻黄 | Chinese ephedra | Ephedra sinica |
| H1248 | Huang Qi Gan Jin Gao | 黄芪干浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0826 | Chu Mu Dan | 臭牡丹 | rose glorybower | Clerodendrum bungei |
| H0957 | Dang Gui Teng | 当归藤 | NA | Embelia parviflora |
| H0555 | Tie Xian Cai | 铁苋菜 | Copperleaf herb | Herba acalyphae |
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum |
| H1250 | Huang Qi Ti Qu Ye | 黄芪提取液 | Membranous milkvetch | Astragalus membranaceus |
| H0200 | Ma Huang Gen | 麻黄根 | Chinese ephedra root | Ephedra sinica |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H0201 | Ma Huang Jin Gao | 麻黄浸膏 | Chinese ephedra | Ephedra sinica |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H1249 | Huang Qi Jin Gao | 黄芪浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
Ckey description of the interaction between compound and target