HIT-result

Type	Detail
Target ID	T46J84
Protein Name	Nicotinamide phosphoribosyltransferase
Uniprot ID	P43490
Protein Name Alias	NAmPRTase; Nampt; EC 2.4.2.12; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin
Gene ID	10135
Gene Symbol	NAMPT
Gene Alias	PBEF; PBEF1
TTD	T54582: Clinical Trial target
Pfam	PF18127 ; PF04095
GO	0070062:extracellular exosome 0008284:positive regulation of cell population proliferation 0034356:NAD biosynthesis via nicotinamide riboside salvage pathway 0004514:nicotinate-nucleotide diphosphorylase (carboxylating) activity 0051770:positive regulation of nitric-oxide synthase biosynthetic process 0005829:cytosol 0032922:circadian regulation of gene expression 0030054:cell junction 0005125:cytokine activity 0042802:identical protein binding 0047280:nicotinamide phosphoribosyltransferase activity 0007165:signal transduction 0045944:positive regulation of transcription by RNA polymerase II 0016607:nuclear speck 0007267:cell-cell signaling
PDB	4JNM ; 4O15 ; 6TAC ; 5UPF ; 4O28 ; 3DHF ; 3DKL ; 6B75 ; 2E5C ; 4LVG ; 4O1B ; 4O17 ; 4M6P ; 4LVF ; 4WQ6 ; 6TA0 ; 4LVD ; 5WI1 ; 5U2M ; 3DHD ; 5UPE ; 5NSD ; 4M6Q ; 6B76 ; 6TA2 ; 2GVJ ; 2E5B ; 2E5D ; 4O18 ; 3DKJ ; 4JR5 ; 4LTS ; 4O1C ; 4LV9 ; 4L4M ; 4N9B ; 4LVA ; 5WI0 ; 3DGR ; 4N9D ; 4O19 ; 5U2N ; 6PEB ; 4N9E ; 5LX5 ; 4O12 ; 6AZJ ; 4L4L ; 4O10 ; 5KIT ; 4O14 ; 4KFO ; 4LWW ; 4O13 ; 4KFP ; 4N9C ; 2GVG ; 4O16 ; 4O0Z ; 6ATB ; 4LVB ; 5LX3 ; 4O1D ; 6E68 ; 4KFN ; 4O1A
Drugbank	DB12731 ; DB05217
KEGG	hsa:10135

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0509	Cang Er	苍耳	Siberian cocklebur	Xanthium sibiricum
H0613	Wu Yue Ai	五月艾	Artemisia	Artemisia princeps
H0246	Mi Ma Huang	蜜麻黄	Ephedra equisetin	Ephedra sinica
H0152	Ling Zhi Jin Gao	灵芝浸膏	NA	Ganoderma lucidum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0045	Jin Fei Cao	金沸草	Japanese inula	Inula japonica
H0198	Ma Huang Gao	麻黄膏	Chinese ephedra	Ephedra sinica
H0002	Hui Xiang	茴香	Fennel fruit	Foeniculum vulgare
H1247	Huang Qi	黄芪	Membranous milkvetch	Astragalus membranaceus
H0197	Ma Huang	麻黄	Chinese ephedra	Ephedra sinica
H1248	Huang Qi Gan Jin Gao	黄芪干浸膏	Membranous milkvetch	Astragalus membranaceus
H0656	Xiao Bo Gen	小檗根	Barberry root	Berberis julianae
H0691	Xue Lian Hua	雪莲花	Snow lotus	Saussurea involucrata
H0289	Niu Bang Zi	牛蒡子	Great burdock fruit	Arctium lappa
H0826	Chu Mu Dan	臭牡丹	rose glorybower	Clerodendrum bungei
H0957	Dang Gui Teng	当归藤	NA	Embelia parviflora
H0555	Tie Xian Cai	铁苋菜	Copperleaf herb	Herba acalyphae
H0705	Yan Hu Lu Ba	盐胡芦巴	Fenugreek	Trigonella foenum-graecum
H1250	Huang Qi Ti Qu Ye	黄芪提取液	Membranous milkvetch	Astragalus membranaceus
H0664	Xiao Ji Tan	小蓟炭	Thistle	Cirsium arvense
H0200	Ma Huang Gen	麻黄根	Chinese ephedra root	Ephedra sinica
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0153	Ling Zhi(1)	灵芝	Lucid ganoderma	Ganoderma lucidum
H0729	Ye Ju Hua	野菊花	Indian wild chrysanthemum flower	Chrysanthemum indicum
H0533	Teng Ku Shen	藤苦参	NA	Sophora flavescens
H0201	Ma Huang Jin Gao	麻黄浸膏	Chinese ephedra	Ephedra sinica
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H1249	Huang Qi Jin Gao	黄芪浸膏	Membranous milkvetch	Astragalus membranaceus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0967	Di Er Cao	地耳草	Japanese stJohn’swort	Hypericum japonicum
H0965	Deng Zhan Xi Xin	灯盏细辛	Shortscape fleabane	Erigeron breviscapus
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0111	Ku Shen	苦参	Lightyellow sophora	Sophora flavescens
H0575	Tu Ku Shen	土苦参	all-grass of hooker winghead	Sophora flavescens
H0514	Cang Er Cao	苍耳草	Cocklebur grass	Xanthium sibiricum
H0690	Xue Lian	雪莲	Snow lotus	Saussurea involucrata
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia
H0546	Tian Shan Xue Lian Hua	天山雪莲花	NA	Saussurea involucrata

Target Description

Related Compounds (Total: 6)

Related Herbs (Total: 41)