Target Description
| Type | Detail |
|---|---|
| Target ID | T93YV8 |
| Protein Name | Tumor necrosis factor receptor superfamily member 11B |
| Uniprot ID |
O00300 |
| Protein Name Alias | Osteoclastogenesis inhibitory factor; Osteoprotegerin |
| Gene ID |
4982 |
| Gene Symbol | TNFRSF11B |
| Gene Alias | OCIF; OPG |
| TTD | T43928: Research target |
| Pfam | PF00531 ; PF00020 |
| GO |
0007584:response to nutrient
0042489:negative regulation of odontogenesis of dentin-containing tooth 0045779:negative regulation of bone resorption 0030198:extracellular matrix organization 0005615:extracellular space 0031012:extracellular matrix 0042493:response to drug 0032026:response to magnesium ion 0005125:cytokine activity 0046685:response to arsenic-containing substance 0001501:skeletal system development 0007165:signal transduction 0005576:extracellular region 0038023:signaling receptor activity 0033209:tumor necrosis factor-mediated signaling pathway 0006915:apoptotic process 0043627:response to estrogen 0005886:plasma membrane |
| PDB | 3URF |
| Drugbank | NA |
| KEGG | hsa:4982 |
Related Compounds (Total: 10)
C0025
Name: Dioscin
C0101
Name: Genistein
C0135
Name: Icariin
C0399
Name: Sesamin
C0721
Name: Baicalin
Related Herbs (Total: 136)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0580 | Tu Si Rou | 菟丝肉 | Dodder seed | Cuscuta australis |
| H0543 | Tian Men Dong | 天门冬 | Cochinchinese asparagus | Asparagus cochinchinensis |
| H0693 | Xue Xie | 血蝎 | Dragon's blood | Daemonorops draco |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
| H1254 | Huang Qin Tan | 黄芩炭 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0096 | Ju San Qi | 菊三七 | NA | Gynura japonica |
| H0581 | Tu Si Zi | 菟丝子 | Dodder seed | Cuscuta australis |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0874 | Chuan Long Shu Yu | 穿龙薯蓣 | Nippon yam | Dioscorea nipponica |
| H0429 | Shao Yao | 芍药 | Red peony root | Paeonia obovata |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H1094 | Ge Gen | 葛根 | Lobed kudzuvine root | Pueraria lobata |
| H1080 | Gan Ge | 干葛 | Lobed kudzuvine root | Pueraria lobata |
| H0789 | Zhang Shu Gen | 樟树根 | Camphor tree | Cinnamomum camphora |
| H1251 | Huang Qin | 黄芩 | Root of Baikal skullcaap | Scutellaria baicalensis |
| H0711 | Yuan Hua Zhi Tiao | 芫花枝条 | stem of lilac daphne | Daphne genkwa |
| H0310 | Pian Qin | 片芩 | Scutellaria amoena | Scutellaria baicalensis |
| H0218 | Man Jiu Jie | 蔓九节 | Creeping ninenode | Psychotria serpens |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0918 | Cu Yuan Hua | 醋芫花 | Lilac daphne | Daphne genkwa |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0123 | La Jiao Liu Jin Gao | 辣椒流浸膏 | Bush redpepper | Capsicum frutescens |
| H0098 | Ju Ye San Qi | 菊叶三七 | NA | Gynura japonica |
| H0751 | Yin Yang Huo | 淫羊藿 | NA | Epimedium brevicornum |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0583 | Tu Si Zi Teng | 菟丝子藤 | Dodder seed | Cuscuta australis |
| H0530 | Tao Ren Shuang | 桃仁霜 | Peach kernel | Prunus persica |
| H0965 | Deng Zhan Xi Xin | 灯盏细辛 | Shortscape fleabane | Erigeron breviscapus |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H0022 | Jia Ju | 假蒟 | Sarmentose pepper | Piper sarmentosum |
| H0158 | Liu Ling Ju | 六棱菊 | NA | Laggera alata |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0753 | Yin Yang Huo Jin Gao | 淫羊藿浸膏 | Epimedium sagittatum | Epimedium brevicornum |
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0531 | Tao Zhi | 桃枝 | Peach juvenile branch | Prunus persica |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H1095 | Ge Gen Gan Jin Gao | 葛根干浸膏 | Lobed kudzuvine root | Pueraria lobata |
| H0792 | Zhang Yu | 章鱼 | Common atlantic octopus | Octopus vulgaris |
| H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
| H0708 | Yuan Hua Gen | 芫花根 | Lilac daphne root | Daphne genkwa |
| H0527 | Tao | 桃 | Peach | Prunus persica |
| H0129 | Le Xian Cai | 勒苋菜 | NA | Amaranthus spinosus |
| H0967 | Di Er Cao | 地耳草 | Japanese stJohn’swort | Hypericum japonicum |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |
| H0820 | Chong Lou | 重楼 | Paris root | Rhizoma paridis |
| H0372 | San Bai Bang | 三百棒 | Chinese asparagus | Asparagus cochinchinensis |
| H1252 | Huang Qin Jin Gao | 黄芩浸膏 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0629 | Xi Xin | 细辛 | Siebold wildginger | Asarum sieboldii |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0788 | Zhang Nao Zi | 樟脑子 | Camphorar | Cinnamomum camphora |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H0752 | Yin Yang Huo Gan Gao Fen | 淫羊藿干膏粉 | Epimedium sagittatum | Epimedium brevicornum |
| H0092 | Ju Hua | 菊花 | Florists chrysanthemum flower | Chrysanthemum morifolium |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0854 | Zi Wei Gen Pi | 紫葳根皮 | NA | Campsis grandiflora |
| H1086 | Bai Hua Cai Zi | 白花菜子 | Common spiderflower seed | Cleome gynandra |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0848 | Zi Jin Niu | 紫金牛 | Japanese ardisia | Ardisia japonica |
| H0295 | Bi Ba | 荜茇 | Long pepper | Piper longum |
| H0852 | Zi Tan | 紫檀 | Burmacoast padauk | Pterocarpus indicus |
| H0790 | Zhang Shu Zi | 樟树子 | Camphor tree | Cinnamomum camphora |
| H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
| H0784 | Chi Shao | 赤芍 | Red peony root | Paeonia obovata |
| H0270 | Mu Hu Die | 木蝴蝶 | Indian trumpetflower | Oroxylum indicum |
| H0866 | Chuan Bi Xie | 川萆薢 | Sichuan castor seed | Dioscorea septemloba |
| H1253 | Huang Qin Jin Gao Fen | 黄芩浸膏粉 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H0119 | La Jiao | 辣椒 | Bush redpepper | Capsicum frutescens |
| H0710 | Yuan Hua Tiao | 芫花条 | stem of lilac daphne | Daphne genkwa |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0164 | Ban Zhi Lian | 半枝莲 | Barbed skullcap | Scutellaria barbata |
| H1161 | Hang Ju | 杭菊 | Chrysanthemum flower | Chrysanthemum morifolium |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0786 | Zhang Mu | 樟木 | Ligum cinmamomi camphorae | Cinnamomum camphora |
| H0787 | Zhang Nao | 樟脑 | Camphorar | Cinnamomum camphora |
| H0707 | Yuan Hua | 芫花 | Lilac daphne | Daphne genkwa |
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum |
| H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
| H0239 | Bei Sha Shen | 北沙参 | Coastal glehnia | Glehnia littoralis |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H0121 | La Jiao Jin Chu Ye | 辣椒浸出液 | Bush redpepper | Capsicum frutescens |
| H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
| H0242 | Bei Sha Shen Liu Jin Gao | 北沙参流浸膏 | Glehnia littoralis | Glehnia littoralis |
| H1096 | Ge Hua | 葛花 | flower bud of lobed kudzuvine | Pueraria lobata |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H0529 | Tao Ren | 桃仁 | Peach kernel | Prunus persica |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0522 | Tai Zi Shen | 太子参 | Heterophylly falsestarwort root | Radix pseudostellariae |
| H0233 | Mao Liang Mian Zhen | 毛两面针 | NA | Zanthoxylum nitidum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0901 | Chun Gen Teng | 春根藤 | Twig and leaf of creeping psychotria | Psychotria serpens |
| H0122 | La Jiao Jin Gao | 辣椒浸膏 | Bush redpepper | Capsicum frutescens |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0906 | Ci Wan | 刺苋 | spiny amaranth | Amaranthus spinosus |
| H0024 | Jia 蒟ye | 假蒟叶 | Sarmentose pepper | Piper sarmentosum |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
| H0537 | Tian Dong | 天冬 | Cochinchinese asparagus root | Asparagus cochinchinensis |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |