| ID: C0025 | Common name: Dioscin | 
| IUPAC: NA | CAS: CAS:19057-60-4 | 
| Chembl ID: CHEMBL507001 | Pubchem ID: CID:119245 | 
| Formula: C45H72O16 | TCM-ID: TCMC1063 | 
| Smiles: OC[C@H]1O[C@@H](O[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3CC[C@]3([C@H]4C[C@H]4[C@@H]3[C@H](C)[C@]3(O4)CC[C@H](CO3)C)C)C2)C)[C@@H]([C@H]([C@@H]1O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O | |
| Alias: 
                        
                        Dioscin; (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside; (+)-Dioscin; 3-O-β-D-α-L-Rhamnopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside-diosgenin; Collettiside III; Dioscine; Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside; Diosgenin 3-O-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside; Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside; Paris III; Parissaponin III; Polyphyllin III | Structure:   | 
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence | 
|---|---|---|---|---|---|
| T24C0P | Bile acid receptor | NR1H4 | Q96RI1 | A | 1 Reference(s) | 
| T16MRU | NACHT, LRR and PYD domains-containing protein 3 | NLRP3 | Q96P20 | A | 1 Reference(s) | 
| T13HKH | Integrin alpha-5 | ITGA5 | P08648 | A | 1 Reference(s) | 
| T84W8G | Aryl hydrocarbon receptor | AHR | P35869 | A | 1 Reference(s) | 
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 | P31749 | B | 1 Reference(s) | 
| T36YWU | Kelch-like ECH-associated protein 1 | KEAP1 | Q14145 | B | 1 Reference(s) | 
| T76B0A | Gap junction alpha-1 protein | GJA1 | P17302 | B | 1 Reference(s) | 
| T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B | O00300 | B | 1 Reference(s) | 
| T34X07 | CCAAT/enhancer-binding protein alpha | CEBPA | P49715 | C | 1 Reference(s) | 
| T51RTI | NA | HOTAIR | NA | C | 1 Reference(s) | 
| T08KXM | Low-density lipoprotein receptor-related protein 5 | LRP5 | O75197 | C | 1 Reference(s) | 
| T05AAL | Microphthalmia-associated transcription factor | MITF | O75030 | C | 1 Reference(s) | 
| T72KIO | Peroxiredoxin-1 | PRDX1 | Q06830 | C | 1 Reference(s) | 
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 | P40763 | C | 1 Reference(s) | 
| T92BZ2 | Catenin beta-1 | CTNNB1 | P35222 | C | 1 Reference(s) | 
| T05O6O | Estrogen receptor beta | ESR2 | Q92731 | C | 1 Reference(s) | 
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name | 
|---|---|---|---|---|
| H0537 | Tian Dong | 天冬 | Cochinchinese asparagus root | Asparagus cochinchinensis | 
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra | 
| H0874 | Chuan Long Shu Yu | 穿龙薯蓣 | Nippon yam | Dioscorea nipponica | 
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china | 
| H0372 | San Bai Bang | 三百棒 | Chinese asparagus | Asparagus cochinchinensis | 
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia | 
| H0820 | Chong Lou | 重楼 | Paris root | Rhizoma paridis | 
| H0866 | Chuan Bi Xie | 川萆薢 | Sichuan castor seed | Dioscorea septemloba | 
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum | 
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia | 
| H0543 | Tian Men Dong | 天门冬 | Cochinchinese asparagus | Asparagus cochinchinensis |