HIT-result

Target Description

Type	Detail
Target ID	T72KIO
Protein Name	Peroxiredoxin-1
Uniprot ID	Q06830
Protein Name Alias	EC 1.11.1.24; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1
Gene ID	5052
Gene Symbol	PRDX1
Gene Alias	PAGA; PAGB; TDPX2
TTD	NA
Pfam	PF10417 ; PF00578
GO	0005634:nucleus 0045454:cell redox homeostasis 0070062:extracellular exosome 0005829:cytosol 0034599:cellular response to oxidative stress 0008379:thioredoxin peroxidase activity 0045321:leukocyte activation 0005615:extracellular space 0019430:removal of superoxide radicals 0001895:retina homeostasis 0003723:RNA binding 0004601:peroxidase activity 0042470:melanosome 0005737:cytoplasm 0045296:cadherin binding 0001501:skeletal system development 0042744:hydrogen peroxide catabolic process 0030101:natural killer cell activation 0008283:cell population proliferation
PDB	2RII ; 4XCS ; 3HY2
Drugbank	DB01593 ; DB14533 ; DB09221 ; DB11638 ; DB09130 ; DB14487 ; DB14548
KEGG	hsa:5052

Type

Detail

Target ID

T72KIO

Protein Name

Peroxiredoxin-1

Uniprot ID

Q06830

Protein Name Alias

EC 1.11.1.24; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1

Gene ID

5052

Gene Symbol

PRDX1

Gene Alias

PAGA; PAGB; TDPX2

TTD

Pfam

PF10417 ; PF00578

0005634:nucleus

0045454:cell redox homeostasis

0070062:extracellular exosome

0005829:cytosol

0034599:cellular response to oxidative stress

0008379:thioredoxin peroxidase activity

0045321:leukocyte activation

0005615:extracellular space

0019430:removal of superoxide radicals

0001895:retina homeostasis

0003723:RNA binding

0004601:peroxidase activity

0042470:melanosome

0005737:cytoplasm

0045296:cadherin binding

0001501:skeletal system development

0042744:hydrogen peroxide catabolic process

0030101:natural killer cell activation

0008283:cell population proliferation

PDB

2RII ; 4XCS ; 3HY2

Drugbank

DB01593 ; DB14533 ; DB09221 ; DB11638 ; DB09130 ; DB14487 ; DB14548

KEGG

hsa:5052

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0172	Lu Gen	芦根	Common reed rhizome	Phragmites communis
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0543	Tian Men Dong	天门冬	Cochinchinese asparagus	Asparagus cochinchinensis
H0372	San Bai Bang	三百棒	Chinese asparagus	Asparagus cochinchinensis
H0537	Tian Dong	天冬	Cochinchinese asparagus root	Asparagus cochinchinensis
H0820	Chong Lou	重楼	Paris root	Rhizoma paridis
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0705	Yan Hu Lu Ba	盐胡芦巴	Fenugreek	Trigonella foenum-graecum
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0882	Chuan Shan Long	穿山龙	Ningpo yam rhizome	Rhizoma dioscoreae nipponicae
H0874	Chuan Long Shu Yu	穿龙薯蓣	Nippon yam	Dioscorea nipponica
H0866	Chuan Bi Xie	川萆薢	Sichuan castor seed	Dioscorea septemloba

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 13)