Herb Description
| Herb ID: H0784 | Chinese Character: 赤芍 |
| English Name: Red peony root | Latin Name: Paeonia obovata |
| Chinese Pin Yin : Chi Shao | TCM-ID: TCMH258 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 185)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T23P74 | Caspase-9 | CASP9 |
P55211 |
5 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
10 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T95Y0K | Sphingosine kinase 1 | SPHK1 |
Q9NYA1 |
1 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
2 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
3 Reference(s) |
| T21K0F | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | ATP2A3 |
Q93084 |
1 Reference(s) |
| T92X7D | Nucleoside diphosphate kinase A | NME1 |
P15531 |
1 Reference(s) |
| T14AON | Nucleoside diphosphate kinase, mitochondrial | NME4 |
O00746 |
1 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
7 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
2 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
3 Reference(s) |
| T36HAE | D-amino-acid oxidase | DAO |
P14920 |
1 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
| T89GFN | Macrophage migration inhibitory factor | MIF |
P14174 |
1 Reference(s) |
| T16X77 | Solute carrier family 15 member 1 | SLC15A1 |
P46059 |
1 Reference(s) |
| T24F1A | Pyruvate kinase PKLR | PKLR |
P30613 |
1 Reference(s) |
| T32JN2 | Beta-glucuronidase | GUSB |
P08236 |
3 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
2 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
| T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
1 Reference(s) |
| T02U6A | Metabotropic glutamate receptor 1 | GRM1 |
Q13255 |
2 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
1 Reference(s) |
| T91N2D | Egl nine homolog 1 | EGLN1 |
Q9GZT9 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
3 Reference(s) |
| T86D6K | Polyunsaturated fatty acid lipoxygenase ALOX15 | ALOX15 |
P16050 |
9 Reference(s) |
| T48NTH | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | PIK3CD |
O00329 |
1 Reference(s) |
| T31JWV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | PIK3CB |
P42338 |
1 Reference(s) |
| T32SPJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PIK3CG |
P48736 |
2 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
| T61SU2 | Coxsackievirus and adenovirus receptor | CXADR |
P78310 |
1 Reference(s) |
| T41INV | Nuclear receptor subfamily 1 group I member 3 | NR1I3 |
Q14994 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
3 Reference(s) |
| T71KM2 | TGF-beta receptor type-1 | TGFBR1 |
P36897 |
1 Reference(s) |
| T15ZAV | Lymphocyte antigen 96 | LY96 |
Q9Y6Y9 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
3 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
5 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
2 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
2 Reference(s) |
| T38N69 | Lymphokine-activated killer T-cell-originated protein kinase | PBK |
Q96KB5 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
3 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
| T31MUM | 5,6-dihydroxyindole-2-carboxylic acid oxidase | TYRP1 |
P17643 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
3 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
1 Reference(s) |
| T65S3S | Tyrosine-protein kinase JAK2 | JAK2 |
O60674 |
1 Reference(s) |
| T43QZ3 | Sclerostin | SOST |
Q9BQB4 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
4 Reference(s) |
| T60A9R | NA | CYP3A |
NA |
2 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
2 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
1 Reference(s) |
| T65JUB | Nucleotide-binding oligomerization domain-containing protein 2 | NOD2 |
Q9HC29 |
2 Reference(s) |
| T61J7T | Mothers against decapentaplegic homolog 2 | SMAD2 |
Q15796 |
1 Reference(s) |
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
1 Reference(s) |
| T09DI4 | Lysine-specific histone demethylase 1A | KDM1A |
O60341 |
1 Reference(s) |
| T73PLT | Sialidase-1 | NEU1 |
Q99519 |
1 Reference(s) |
| T32REB | Calcium/calmodulin-dependent protein kinase type II subunit gamma | CAMK2G |
Q13555 |
1 Reference(s) |
| T33JS5 | CCN family member 2 | CCN2 |
P29279 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
2 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
2 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
5 Reference(s) |
| T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
1 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T16UZ4 | Dipeptidyl peptidase 4 | DPP4 |
P27487 |
1 Reference(s) |
| T31ZFD | Aldehyde oxidase | AOX1 |
Q06278 |
1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
7 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
7 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T76EHP | Glutathione S-transferase A1 | GSTA1 |
P08263 |
1 Reference(s) |
| T48XM4 | Glutathione S-transferase Mu 2 | GSTM2 |
P28161 |
1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
1 Reference(s) |
| T87WYU | Glutathione S-transferase Mu 1 | GSTM1 |
P09488 |
1 Reference(s) |
| T24CYX | Chitin synthase 2 | CHS2 |
P14180 |
1 Reference(s) |
| T46AQJ | Glutathione S-transferase P | GSTP1 |
P09211 |
1 Reference(s) |
| T62F1Y | Glutathione S-transferase A2 | GSTA2 |
P09210 |
1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
2 Reference(s) |
| T10KMJ | Insulin-like growth factor II | IGF2 |
P01344 |
2 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
2 Reference(s) |
| T47DIY | ATP-dependent 6-phosphofructokinase, muscle type | PFKM |
P08237 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
2 Reference(s) |
| T48J1U | Aldo-keto reductase family 1 member C1 | AKR1C1 |
Q04828 |
1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
| T92HNO | High mobility group protein B1 | HMGB1 |
P09429 |
1 Reference(s) |
| T23Z2G | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH |
P04406 |
1 Reference(s) |
| T97F4Y | High mobility group protein B3 | HMGB3 |
O15347 |
1 Reference(s) |
| T41S16 | Atrial natriuretic peptide receptor 3 | NPR3 |
P17342 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T02QZI | NADPH oxidase 5 | NOX5 |
Q96PH1 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
5 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
2 Reference(s) |
| T87WH7 | Fos-related antigen 2 | FOSL2 |
P15408 |
2 Reference(s) |
| T16UHV | Nuclear factor of activated T-cells, cytoplasmic 1 | NFATC1 |
O95644 |
2 Reference(s) |
| T54N7G | Fos-related antigen 1 | FOSL1 |
P15407 |
1 Reference(s) |
| T35QZO | Cytochrome c | CYCS |
P99999 |
2 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
1 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
2 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
1 Reference(s) |
| T66G0O | NA | MIR30A |
NA |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
| T22H8P | Carbonic anhydrase 3 | CA3 |
P07451 |
1 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T29B10 | Interleukin-17A | IL17A |
Q16552 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
2 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
3 Reference(s) |
| T97KL5 | Microsomal glutathione S-transferase 1 | MGST1 |
P10620 |
2 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
3 Reference(s) |
| T81BH5 | Sulfotransferase 1A1 | SULT1A1 |
P50225 |
2 Reference(s) |
| T02P7Q | Dihydrofolate reductase | DHFR |
P00374 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T42FMQ | Mitogen-activated protein kinase kinase kinase 1 | MAP3K1 |
Q13233 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
2 Reference(s) |
| T02FO3 | Golgi-associated plant pathogenesis-related protein 1 | GLIPR2 |
Q9H4G4 |
1 Reference(s) |
| T10I26 | Interferon beta | IFNB1 |
P01574 |
1 Reference(s) |
| T14JSX | Plasminogen | PLG |
P00747 |
1 Reference(s) |
| T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
| T20PAH | Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed] | FTH1 |
P02794 |
1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
1 Reference(s) |
| T46K2X | Heat shock 70 kDa protein 4 | HSPA4 |
P34932 |
1 Reference(s) |
| T86DIE | Folate binding protein | NA |
Q6LDL1 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T87C5Q | Polyunsaturated fatty acid lipoxygenase ALOX12 | ALOX12 |
P18054 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T54WR0 | Fatty acid-binding protein 5 | FABP5 |
Q01469 |
1 Reference(s) |
| T58TOI | Apolipoprotein D | APOD |
P05090 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T63YAO | Caveolin-1 | CAV1 |
Q03135 |
1 Reference(s) |
| T68OIU | CREB-regulated transcription coactivator 1 | CRTC1 |
Q6UUV9 |
1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
2 Reference(s) |
| T21UJU | Troponin I, cardiac muscle | TNNI3 |
P19429 |
1 Reference(s) |
| T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
| T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
1 Reference(s) |
| T12PV0 | NA | MEG3 |
NA |
1 Reference(s) |
| T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B |
O00300 |
1 Reference(s) |
| T47G3X | Glucocorticoid receptor | NR3C1 |
P04150 |
1 Reference(s) |
| T08Q1T | Amiloride-sensitive sodium channel subunit alpha | SCNN1A |
P37088 |
1 Reference(s) |
| T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
1 Reference(s) |
| T57L0X | Oxysterols receptor LXR-alpha | NR1H3 |
Q13133 |
1 Reference(s) |
| T99ARN | Forkhead box protein P3 | FOXP3 |
Q9BZS1 |
1 Reference(s) |
| T39XYV | Dickkopf-related protein 1 | DKK1 |
O94907 |
1 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
| T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
| T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
| T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T08B2M | M-phase inducer phosphatase 1 | CDC25A |
P30304 |
1 Reference(s) |
| T33UEM | Lactoperoxidase | LPO |
P22079 |
1 Reference(s) |
| T03TJ0 | Interleukin-33 | IL33 |
O95760 |
1 Reference(s) |
| T40G6B | Prostaglandin reductase 1 | PTGR1 |
Q14914 |
1 Reference(s) |
| T31VDH | Myeloid differentiation primary response protein MyD88 | MYD88 |
Q99836 |
1 Reference(s) |
| T71ZSO | High affinity immunoglobulin epsilon receptor subunit alpha | FCER1A |
P12319 |
1 Reference(s) |
| T30OID | Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 | COL18A1 |
P39060 |
1 Reference(s) |
| T49XOZ | Krueppel-like factor 7 | KLF7 |
O75840 |
1 Reference(s) |
Related Compounds (Total: 16)
C1178
Name: Beta-Sitosterol
C0039
Name: Ellagic Acid
C1166
Name: Benzoic Acid
C0383
Name: Salicylic Acid
C0130
Name: Hydroquinone
key description of the interaction between compound and target