Compound Description
| ID: C0383 | Common name: Salicylic Acid |
| IUPAC: 2-hydroxybenzoic acid | CAS: CAS:69-72-7 |
| Chembl ID: CHEMBL424 | Pubchem ID: CID:338 |
| Formula: C7H6O3 | TCM-ID: TCMC2037 |
| Smiles: C1=CC=C(C(=C1)C(=O)O)O | |
| Alias:
Salicylic acid;
2-Hydroxybenzoic acid; 171; 2-Carboxyphenol; 2-Hydroxybenzenecarboxylic acid; 311; 334; 337; 380; Advanced Pain Relief Callus Removers; Advanced Pain Relief Corn Removers; Clear away Wart Remover; Compound W; Dr. Scholl's Callus Removers; Dr. Scholl's Corn Removers; Dr. Scholl's Wart Remover Kit; Duofil Wart Remover; Duoplant; Freezone; Ionil; Ionil Plus; K 537; K 557; NSC 180; Phenol-2-carboxylic acid; Psoriacid-S-Stift; Retarder W; Rutranex; Salicylic Acid Soap; Salicylic acid collodion; Saligel; Salonil; Salvona Nanosal; Stri-Dex; Trans-Ver-Sal; Verrugon; o-Carboxyphenol; o-Hydroxybenzoic acid |
Structure:
|
Related Targets (Total: 27)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T24F1A | Pyruvate kinase PKLR | PKLR |
P30613 |
A | 1 Reference(s) |
| T32JN2 | Beta-glucuronidase | GUSB |
P08236 |
A | 1 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
A | 1 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
A | 1 Reference(s) |
| T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
A | 1 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
B | 1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
B | 1 Reference(s) |
| T47DIY | ATP-dependent 6-phosphofructokinase, muscle type | PFKM |
P08237 |
B | 1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
B | 1 Reference(s) |
| T48J1U | Aldo-keto reductase family 1 member C1 | AKR1C1 |
Q04828 |
B | 1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
B | 1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
B | 1 Reference(s) |
| T92HNO | High mobility group protein B1 | HMGB1 |
P09429 |
B | 1 Reference(s) |
| T23Z2G | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH |
P04406 |
B | 1 Reference(s) |
| T97F4Y | High mobility group protein B3 | HMGB3 |
O15347 |
B | 1 Reference(s) |
| T41S16 | Atrial natriuretic peptide receptor 3 | NPR3 |
P17342 |
B | 1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
B | 1 Reference(s) |
| T02FO3 | Golgi-associated plant pathogenesis-related protein 1 | GLIPR2 |
Q9H4G4 |
C | 1 Reference(s) |
| T10I26 | Interferon beta | IFNB1 |
P01574 |
C | 1 Reference(s) |
| T14JSX | Plasminogen | PLG |
P00747 |
C | 1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
C | 1 Reference(s) |
| T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
C | 1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
C | 1 Reference(s) |
| T20PAH | Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed] | FTH1 |
P02794 |
C | 1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
C | 1 Reference(s) |
| T46K2X | Heat shock 70 kDa protein 4 | HSPA4 |
P34932 |
C | 1 Reference(s) |
| T86DIE | Folate binding protein | NA |
Q6LDL1 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 62)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0937 | Da Qing Ye | 大青叶 | Indigo-coloured woad leaf | Isatis indigotica |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1044 | Feng Wei Cao | 凤尾草 | Chinese brake | Pteris multifida |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0137 | Ban Lan Gen | 板蓝根 | Indigowoad root | Isatis indigotica |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H0312 | Po Gu Zhi | 破故纸 | fruit of malaytea scurfpea | Fructus psoraleae corylifoliae |
| H0447 | Sheng Ma | 升麻 | Bugbane | Cimicifuga foetida |
| H0263 | Mu Ban Lan Gen | 木板蓝根 | Indigowoad root | Isatis indigotica |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0803 | Zhi Huang Jing | 制黄精 | Prepared rhizome of fragrant solomonseal | Polygonatum sibiricum |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1038 | Feng Fang | 蜂房 | Honeycomb | Nidus vespae |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H0265 | Mu Da Qing Ye | 木大青叶 | Indigo-coloured woad leaf equivalent | Isatis indigotica |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H1113 | Guan Bai Fu | 关白附 | Korean monk's hood | Aconitum coreanum |
| H0445 | Sheng Guan Bai Fu | 生关白附 | NA | Aconitum coreanum |
| H0718 | Yang Jiao Qi | 羊角七 | NA | Bletilla striata |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H1235 | Huang Hao | 黄蒿 | Virg ate wormwood | Artemisia scoparia |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0131 | Ban Lan | 板蓝 | Indigowoad root | Isatis indigotica |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0784 | Chi Shao | 赤芍 | Red peony root | Paeonia obovata |
| H1239 | Huang Jing Gan Jin Gao | 黄精干浸膏 | NA | Polygonatum sibiricum |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0215 | Mai Ya | 麦芽 | Barley germinating fruit | Hordeum vulgare |
| H1118 | Bai Ji | 白芨 | Common bletilla | Bletilla striata |
| H1221 | Hua Xiang Shu Guo Xu | 化香树果序 | NA | Platycarya strobilacea |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H1056 | Fu Pen Zi | 覆盆子 | Red-and-Yellow garden raspberry | Rubus idaeus |
| H0081 | Jiu Huang Jing | 酒黄精 | Siberian solomonseal | Polygonatum sibiricum |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H1220 | Hua Xiang Shu Guo | 化香树果 | NA | Platycarya strobilacea |
| H1036 | Fen Dan Pi | 粉丹皮 | Tree peony bark | Paeonia suffruticosa |
| H0429 | Shao Yao | 芍药 | Red peony root | Paeonia obovata |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H1238 | Huang Jing | 黄精 | Siberian solomonseal | Polygonatum sibiricum |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
Ckey description of the interaction between compound and target