HIT-result

Type	Detail
Target ID	T31VDH
Protein Name	Myeloid differentiation primary response protein MyD88
Uniprot ID	Q99836
Protein Name Alias	NA
Gene ID	4615
Gene Symbol	MYD88
Gene Alias	NA
TTD	T75476: Research target
Pfam	PF01582 ; PF00531
GO	0070555:response to interleukin-1 0002755:MyD88-dependent toll-like receptor signaling pathway 0032991:protein-containing complex 0050671:positive regulation of lymphocyte proliferation 0034162:toll-like receptor 9 signaling pathway 0002269:leukocyte activation involved in inflammatory response 0035325:Toll-like receptor binding 0016064:immunoglobulin mediated immune response 0009682:induced systemic resistance 0005121:Toll binding 0032755:positive regulation of interleukin-6 production 0043066:negative regulation of apoptotic process 0032722:positive regulation of chemokine production 0008063:Toll signaling pathway 0031663:lipopolysaccharide-mediated signaling pathway 0032760:positive regulation of tumor necrosis factor production 0002283:neutrophil activation involved in immune response 0071260:cellular response to mechanical stimulus 1900017:positive regulation of cytokine production involved in inflammatory response 0032757:positive regulation of interleukin-8 production 1902622:regulation of neutrophil migration 0090557:establishment of endothelial intestinal barrier 0070498:interleukin-1-mediated signaling pathway 0070976:TIR domain binding 0070944:neutrophil-mediated killing of bacterium 0005829:cytosol 0042742:defense response to bacterium 0042802:identical protein binding 0050830:defense response to Gram-positive bacterium 0007166:cell surface receptor signaling pathway 0032481:positive regulation of type I interferon production 0006915:apoptotic process 0070935:3'-UTR-mediated mRNA stabilization 0005886:plasma membrane 0005737:cytoplasm 0045087:innate immune response 0032747:positive regulation of interleukin-23 production 0046330:positive regulation of JNK cascade 0048661:positive regulation of smooth muscle cell proliferation 0005149:interleukin-1 receptor binding 0009615:response to virus 0140052:cellular response to oxidised low-density lipoprotein particle stimulus 2000341:regulation of chemokine (C-X-C motif) ligand 2 production 0032494:response to peptidoglycan 0005634:nucleus 0071222:cellular response to lipopolysaccharide 0010008:endosome membrane 0002238:response to molecule of fungal origin 0002224:toll-like receptor signaling pathway 0007254:JNK cascade 0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling 0010628:positive regulation of gene expression 0032740:positive regulation of interleukin-17 production 0014069:postsynaptic density 0051092:positive regulation of NF-kappaB transcription factor activity 2000338:regulation of chemokine (C-X-C motif) ligand 1 production 0005123:death receptor binding 0007165:signal transduction 0043621:protein self-association 0060337:type I interferon signaling pathway 0006909:phagocytosis 0042832:defense response to protozoan 0050727:regulation of inflammatory response
PDB	2JS7 ; 3MOP ; 4DOM ; 2Z5V ; 4EO7 ; 6I3N
Drugbank	NA
KEGG	hsa:4615

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Name: Gallic Acid

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Name: Morphine

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Name: Propranolol

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Name: Zingerone

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Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0064	Jin Yin Hua	金银花	Japanese honeysuckle	Lonicera japonica
H0648	Xiang Si Teng	相思藤	Coralhead plant vine	Abrus precatorius
H1127	Guang Shan Zha	广山楂	Chinese hawthorn	Crataegus pinnatifida
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0695	Ya Dan Zi	鸦胆子	Java brucea	Brucea javanica
H1090	Gao Ben	藁本	Chinese ligusticum	Ligusticum sinense
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0043	Jie Zi	芥子	India mustard seed	Brassica juncea
H1061	Bai He	百合	Lily	Lilium brownii
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides
H0344	Qing Guo	青果	Olive	Canarium album
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0419	Shan Zha	山楂	Chinese hawthorn	Crataegus pinnatifida
H0424	Shan Zhi	山栀	Cape jasmine	Gardenia jasminoides
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0860	Zong Lv Zi	棕榈子	NA	Trachycarpus fortunei
H1049	Feng Xiang Zhi Chou Gao	枫香脂稠膏	NA	Liquidambar formosana
H0302	Ou Fen	藕粉	Hindu lotus large rhizome	Nelumbo nucifera
H0115	Kuan Dong Hua	款冬花	Common coltsfoot	Tussilago farfara
H0177	Lu Lu Tong	路路通	Beautiful sweetgum	Liquidambar formosana
H0345	Qing Guo Tan	青果炭	white olive	Canarium album
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0897	Chuan Lian	川楝	Chinaberry	Melia azedarach
H0461	Shi Jun Zi Ren	使君子仁	NA	Combretum indicum
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0784	Chi Shao	赤芍	Red peony root	Paeonia obovata
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0255	Mao Zhao Cao	猫爪草	Root of catclaw buttercup	Ranunculus ternatus
H0065	Jin Yin Hua Ti Qu Ye	金银花提取液	Japanese honeysuckle	Lonicera japonica
H1047	Feng Xiang Ye	枫香叶	NA	Liquidambar formosana
H0857	Zong Ban Tan	棕板炭	NA	Trachycarpus fortunei
H1068	Bai He Liu Jin Gao	百合流浸膏	Lily	Lilium brownii
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0185	Luo Shi Teng	络石藤	Chinese star jasmine	Trachelospermum jasminoides
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H1244	Huang Miao	黄苗	NA	Taraxacum mongolicum
H1036	Fen Dan Pi	粉丹皮	Tree peony bark	Paeonia suffruticosa
H1034	Fei Yang Cao	飞杨草	NA	Euphorbia hirta
H0429	Shao Yao	芍药	Red peony root	Paeonia obovata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0998	Dong Gua Pi	冬瓜皮	Chinese waxgourd peel	Benincasa hispida
H1009	Du Huo	独活	Doubleteeth pubescent angelica	Angelica pubescens
H1130	Guang Zao	广枣	fruit of axillary choerospondias	Fructus choerospondiatis
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H0540	Tian Ji Huang	田基黄	all - grass of japanese st. johnswort	Grangea maderaspatana
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0591	Wei Ling Cai	委陵菜	Chinese cinquefoil	Potentilla chinensis
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum
H0972	Di Huang	地黄	Rehmanniae	Rehmannia glutinosa
H0470	Shi Ye	柿叶	Persimmon leaf	Diospyros kaki
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0868	Chuan Du Huo	川独活	Doubleteeth pubescent angelica	Angelica pubescens
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0120	Ban Bian Qi	半边旗	pinnated brake herb	Pteris semipinnata
H0856	Zong Ban	棕板	NA	Trachycarpus fortunei
H0703	Yan Fu Mu	盐肤木	Chinese sumac	Rhus chinensis
H0109	Ku Lian Zi	苦楝子	NA	Melia azedarach
H0692	Xue Ren Shen	血人参	NA	Lespedeza bicolor
H0974	Di Jin Cao	地锦草	Humifuse euphorbia	Euphorbia humifusa
H0420	Shan Zha Chou Gao	山楂稠膏	Chinese hawthorn	Crataegus pinnatifida
H0395	Sang Shen Qing Gao	桑葚清膏	Mulberry	Morus alba
H0069	Jin Ying Zi Ti Qu Ye	金樱子提取液	Cherokee rose seed	Rosa laevigata
H0594	Wu Bei Zi	五倍子	Chinese gall	Galla chinensis
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H1188	Hong Hua	红花	Safflower	Carthamus tinctorius
H0569	Tu Er San	兔儿伞	Syneilesis*	Syneilesis palmata
H1097	Gong Ding Xiang	公丁香	NA	Syzygium aromaticum
H0979	Di Yu	地榆	Garden burnet	Sanguisorba officinalis
H0243	Mi Kuan Dong Hua	蜜款冬花	Common coltsfoot	Tussilago farfara
H0670	Chai Pi Zhang	豺皮樟	Oblong-leaved litsea	Litsea rotundifolia
H0060	Jin Si Ku Lian	金丝苦楝	NA	Cardiospermum halicacabum
H1027	Fan Shi Liu Ye	番石榴叶	Guava leaf	Psidium guajava
H0566	Cao Cong Rong	草苁蓉	Russian boschniakia	Boschniakia rossica
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0141	Lian Zi Xin	莲子心	Hindu lotus plumule	Nelumbo nucifera
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1201	Hu Er Cao	虎耳草	Creeping rockfoil	Saxifraga stolonifera
H1221	Hua Xiang Shu Guo Xu	化香树果序	NA	Platycarya strobilacea
H1082	Gan Lan	橄榄	Cabbage	Canarium album
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0519	Suo Yang	锁阳	Songaria cynomorium	Cynomorium songaricum
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H1171	He Zi Rou	诃子肉	Medicine terminalia	Terminalia chebula
H0635	Xian He Cao Jin Gao Fen	仙鹤草浸膏粉	Japanese argimonia	Agrimonia pilosa var. japonica
H0304	Ou Pian	藕片	Hindu lotus large rhizome	Nelumbo nucifera
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia
H0067	Jin Ying Zi	金樱子	Cherokee rose seed	Rosa laevigata
H0427	Shan Zhu Yu	山茱萸	Asiatic cornelian cherry	Cornus officinalis
H0365	Rou Dou Kou	肉豆蔻	Common nutmeg	Myristica fragrans
H0152	Ling Zhi Jin Gao	灵芝浸膏	NA	Ganoderma lucidum
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0422	Shan Zha Tan	山楂炭	Chinese hawthorn	Crataegus pinnatifida
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H1170	He Zi	诃子	Medicine terminalia	Terminalia chebula
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0848	Zi Jin Niu	紫金牛	Japanese ardisia	Ardisia japonica
H0721	Yang Mei Gen	杨梅根	Myrica rubra sieb. et zucc	Myrica rubra
H0656	Xiao Bo Gen	小檗根	Barberry root	Berberis julianae
H0798	Zhen Zhu Cao	珍珠草	chamber bitter	Phyllanthus urinaria
H0393	Sang Shen	桑葚	Mulberry	Morus alba
H0237	Mei Gui Hua	玫瑰花	Rugose rose flower	Rosa rugosa
H0440	Sheng Di Hong Jing Tian	圣地红景天	Integripetal rhodiola	Rhodiola sacra
H0354	Ren Dong Teng	忍冬藤	Japanese honeysuckle vine	Lonicera japonica
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0085	Jiu Yu Rou	酒萸肉	Asiatic cornelian cherry	Cornus officinalis
H1184	Bai Lian	白蔹	Japanese ampelopsis	Ampelopsis japonica
H0819	Zhi Zi Jin Gao	栀子浸膏	Cape jasmine fruit	Gardenia jasminoides
H1137	Gui Yuan	桂圆	NA	Dimocarpus longan
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0464	Shi Liu Zi	石榴子	NA	Punica granatum
H1079	Gan Di Huang	干地黄	Adhesive rehmannia dried root	Rehmannia glutinosa
H0108	Ku Lian Pi	苦楝皮	Chinaberry-tree bark	Melia azedarach
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H0179	Lu Xian Cao	鹿衔草	Chinese pyrola	Pyrola calliantha
H0990	Ding Xiang	丁香	Clove tree	Syzygium aromaticum
H0314	Pu Gong Ying	蒲公英	Mongolian dandelion	Taraxacum mongolicum
H0315	Pu Gong Ying Jin Gao	蒲公英浸膏	Mongolian dandelion	Taraxacum mongolicum
H0858	Zong Lv Pi	棕榈皮	Fortune windmillpalm	Trachycarpus fortunei
H0421	Shan Zha Qing Gao	山楂清膏	Chinese hawthorn	Crataegus pinnatifida
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H1156	Ai Di Huang	矮地黄	Rehmanniae	Rehmannia glutinosa
H1000	Dong Gua Zi	冬瓜子	Chinese waxgourd seed	Benincasa hispida
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0634	Xian He Cao	仙鹤草	Japanese argimonia	Agrimonia pilosa var. japonica
H0128	Lao Guan Cao	老鹳草	Wilford cranesbill	Geranium wilfordii
H0453	Shi Di	柿蒂	Persimmon persistent calyx	Diospyros kaki
H0166	Long Kui	龙葵	Black nightshade	Solanum nigrum
H0973	Di Huang Tan	地黄炭	Rehmanniae	Rehmannia glutinosa
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0214	Bei He Huan	北合欢	Albizia	Albizia julibrissin
H0104	Bai Zhu	白术	Largehead atractylodes	Atractylodes macrocephala
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0734	Ye Xia Zhu	叶下珠	Common leafflower	Phyllanthus urinaria
H0379	Bian Xu	萹蓄	Common knotgrass	Polygonum aviculare
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1152	Bai Jie Zi	白芥子	White mustard seed	Sinapis alba
H0733	Ye Shan Zha	野山楂	nippon bawthorn	Crataegus pinnatifida
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu
H0772	Yue Ji Hua	月季花	Chinese rose	Rosa chinensis
H0068	Jin Ying Zi Rou	金樱子肉	Cherokee rose seed	Rosa laevigata
H0567	Tu Da Huang	土大黄	NA	Rumex obtusifolius
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H1164	He Geng	荷梗	Hindu lotus petiole	Nelumbo nucifera
H0705	Yan Hu Lu Ba	盐胡芦巴	Fenugreek	Trigonella foenum-graecum
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0351	Quan Shen	拳参	Bistort	Polygonum bistorta
H0301	Ou	藕	Hindu lotus large rhizome	Nelumbo nucifera
H0975	Di Mian Cao	地绵草	NA	Euphorbia humifusa
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0153	Ling Zhi(1)	灵芝	Lucid ganoderma	Ganoderma lucidum
H0941	Da Zao	大枣	Chinese date	Ziziphus jujuba
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0012	Ji Mu Ye Jin Gao	继木叶浸膏	NA	Loropetalum chinense
H0511	Su Mu	苏木	Sappan caesalpinia	Caesalpinia sappan
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H1220	Hua Xiang Shu Guo	化香树果	NA	Platycarya strobilacea
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0547	Cang Qing Guo	藏青果	Myrobalan	Terminalia chebula
H0649	Xiang Si Zi	相思子	Coralhead plant	Abrus precatorius
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0980	Di Yu Tan	地榆炭	Garden burnet	Sanguisorba officinalis
H0394	Sang Shen Jin Gao	桑葚浸膏	Mulberry	Morus alba
H0473	Shu Di Huang	熟地黄	Adhesive rehmannia cocked root	Rehmannia glutinosa
H0259	Mo Shi Zi	没食子	Aleppo gall	Quercus infectoria

Target Description

Related Compounds (Total: 5)

Related Herbs (Total: 176)