Target Description

Type Detail
Target ID T31VDH
Protein Name Myeloid differentiation primary response protein MyD88
Uniprot ID Q99836
Protein Name Alias NA
Gene ID 4615
Gene Symbol MYD88
Gene Alias NA
TTD T75476: Research target
Pfam PF01582 ; PF00531
GO
0070555:response to interleukin-1

0002755:MyD88-dependent toll-like receptor signaling pathway

0032991:protein-containing complex

0050671:positive regulation of lymphocyte proliferation

0034162:toll-like receptor 9 signaling pathway

0002269:leukocyte activation involved in inflammatory response

0035325:Toll-like receptor binding

0016064:immunoglobulin mediated immune response

0009682:induced systemic resistance

0005121:Toll binding

0032755:positive regulation of interleukin-6 production

0043066:negative regulation of apoptotic process

0032722:positive regulation of chemokine production

0008063:Toll signaling pathway

0031663:lipopolysaccharide-mediated signaling pathway

0032760:positive regulation of tumor necrosis factor production

0002283:neutrophil activation involved in immune response

0071260:cellular response to mechanical stimulus

1900017:positive regulation of cytokine production involved in inflammatory response

0032757:positive regulation of interleukin-8 production

1902622:regulation of neutrophil migration

0090557:establishment of endothelial intestinal barrier

0070498:interleukin-1-mediated signaling pathway

0070976:TIR domain binding

0070944:neutrophil-mediated killing of bacterium

0005829:cytosol

0042742:defense response to bacterium

0042802:identical protein binding

0050830:defense response to Gram-positive bacterium

0007166:cell surface receptor signaling pathway

0032481:positive regulation of type I interferon production

0006915:apoptotic process

0070935:3'-UTR-mediated mRNA stabilization

0005886:plasma membrane

0005737:cytoplasm

0045087:innate immune response

0032747:positive regulation of interleukin-23 production

0046330:positive regulation of JNK cascade

0048661:positive regulation of smooth muscle cell proliferation

0005149:interleukin-1 receptor binding

0009615:response to virus

0140052:cellular response to oxidised low-density lipoprotein particle stimulus

2000341:regulation of chemokine (C-X-C motif) ligand 2 production

0032494:response to peptidoglycan

0005634:nucleus

0071222:cellular response to lipopolysaccharide

0010008:endosome membrane

0002238:response to molecule of fungal origin

0002224:toll-like receptor signaling pathway

0007254:JNK cascade

0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling

0010628:positive regulation of gene expression

0032740:positive regulation of interleukin-17 production

0014069:postsynaptic density

0051092:positive regulation of NF-kappaB transcription factor activity

2000338:regulation of chemokine (C-X-C motif) ligand 1 production

0005123:death receptor binding

0007165:signal transduction

0043621:protein self-association

0060337:type I interferon signaling pathway

0006909:phagocytosis

0042832:defense response to protozoan

0050727:regulation of inflammatory response

PDB 2JS7 ; 3MOP ; 4DOM ; 2Z5V ; 4EO7 ; 6I3N
Drugbank NA
KEGG hsa:4615

Related Compounds  (Total: 5)

Go to browser
C0090
Name: Gallic Acid
Go to browser
C0226
Name: Morphine
Go to browser
C0327
Name: Propranolol
Go to browser
C0605
Name: Zingerone
Go to browser
C0739
Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione


Related Herbs  (Total: 176)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0648 Xiang Si Teng相思藤 Coralhead plant vineAbrus precatorius
H1127 Guang Shan Zha广山楂 Chinese hawthornCrataegus pinnatifida
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0695 Ya Dan Zi鸦胆子 Java bruceaBrucea javanica
H1090 Gao Ben藁本 Chinese ligusticumLigusticum sinense
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0043 Jie Zi芥子 India mustard seedBrassica juncea
H1061 Bai He百合 LilyLilium brownii
H0818 Zhi Zi栀子 Cape jasmine fruitGardenia jasminoides
H0344 Qing Guo青果 OliveCanarium album
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0419 Shan Zha山楂 Chinese hawthornCrataegus pinnatifida
H0424 Shan Zhi山栀 Cape jasmineGardenia jasminoides
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0860 Zong Lv Zi棕榈子 NATrachycarpus fortunei
H1049 Feng Xiang Zhi Chou Gao枫香脂稠膏 NALiquidambar formosana
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H0115 Kuan Dong Hua款冬花 Common coltsfootTussilago farfara
H0177 Lu Lu Tong路路通 Beautiful sweetgumLiquidambar formosana
H0345 Qing Guo Tan青果炭 white oliveCanarium album
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0897 Chuan Lian川楝 ChinaberryMelia azedarach
H0461 Shi Jun Zi Ren使君子仁 NACombretum indicum
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0784 Chi Shao赤芍 Red peony rootPaeonia obovata
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0255 Mao Zhao Cao猫爪草 Root of catclaw buttercupRanunculus ternatus
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1047 Feng Xiang Ye枫香叶 NALiquidambar formosana
H0857 Zong Ban Tan棕板炭 NATrachycarpus fortunei
H1068 Bai He Liu Jin Gao百合流浸膏 LilyLilium brownii
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0185 Luo Shi Teng络石藤 Chinese star jasmineTrachelospermum jasminoides
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H1036 Fen Dan Pi粉丹皮 Tree peony barkPaeonia suffruticosa
H1034 Fei Yang Cao飞杨草 NAEuphorbia hirta
H0429 Shao Yao芍药 Red peony rootPaeonia obovata
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0998 Dong Gua Pi冬瓜皮 Chinese waxgourd peelBenincasa hispida
H1009 Du Huo独活 Doubleteeth pubescent angelicaAngelica pubescens
H1130 Guang Zao广枣 fruit of axillary choerospondiasFructus choerospondiatis
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H0540 Tian Ji Huang田基黄 all - grass of japanese st. johnswortGrangea maderaspatana
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0591 Wei Ling Cai委陵菜 Chinese cinquefoilPotentilla chinensis
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H0972 Di Huang地黄 RehmanniaeRehmannia glutinosa
H0470 Shi Ye柿叶 Persimmon leafDiospyros kaki
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0868 Chuan Du Huo川独活 Doubleteeth pubescent angelicaAngelica pubescens
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0120 Ban Bian Qi半边旗 pinnated brake herbPteris semipinnata
H0856 Zong Ban棕板 NATrachycarpus fortunei
H0703 Yan Fu Mu盐肤木 Chinese sumacRhus chinensis
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0692 Xue Ren Shen血人参 NALespedeza bicolor
H0974 Di Jin Cao地锦草 Humifuse euphorbiaEuphorbia humifusa
H0420 Shan Zha Chou Gao山楂稠膏 Chinese hawthornCrataegus pinnatifida
H0395 Sang Shen Qing Gao桑葚清膏 MulberryMorus alba
H0069 Jin Ying Zi Ti Qu Ye金樱子提取液 Cherokee rose seedRosa laevigata
H0594 Wu Bei Zi五倍子 Chinese gallGalla chinensis
H0472 Shu Da Huang熟大黄 NARheum palmatum
H1188 Hong Hua红花 SafflowerCarthamus tinctorius
H0569 Tu Er San兔儿伞 Syneilesis*Syneilesis palmata
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H0243 Mi Kuan Dong Hua蜜款冬花 Common coltsfootTussilago farfara
H0670 Chai Pi Zhang豺皮樟 Oblong-leaved litseaLitsea rotundifolia
H0060 Jin Si Ku Lian金丝苦楝 NACardiospermum halicacabum
H1027 Fan Shi Liu Ye番石榴叶 Guava leafPsidium guajava
H0566 Cao Cong Rong草苁蓉 Russian boschniakiaBoschniakia rossica
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1201 Hu Er Cao虎耳草 Creeping rockfoilSaxifraga stolonifera
H1221 Hua Xiang Shu Guo Xu化香树果序 NAPlatycarya strobilacea
H1082 Gan Lan橄榄 CabbageCanarium album
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0519 Suo Yang锁阳 Songaria cynomoriumCynomorium songaricum
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H1171 He Zi Rou诃子肉 Medicine terminaliaTerminalia chebula
H0635 Xian He Cao Jin Gao Fen仙鹤草浸膏粉 Japanese argimoniaAgrimonia pilosa var. japonica
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0278 Nan Ban Lan Gen Jin Gao Fen南板蓝根浸膏粉 Indigowoad rootBaphicacanthus cusia
H0067 Jin Ying Zi金樱子 Cherokee rose seedRosa laevigata
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0422 Shan Zha Tan山楂炭 Chinese hawthornCrataegus pinnatifida
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H1170 He Zi诃子 Medicine terminaliaTerminalia chebula
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0848 Zi Jin Niu紫金牛 Japanese ardisiaArdisia japonica
H0721 Yang Mei Gen杨梅根 Myrica rubra sieb. et zuccMyrica rubra
H0656 Xiao Bo Gen小檗根 Barberry rootBerberis julianae
H0798 Zhen Zhu Cao珍珠草 chamber bitterPhyllanthus urinaria
H0393 Sang Shen桑葚 MulberryMorus alba
H0237 Mei Gui Hua玫瑰花 Rugose rose flowerRosa rugosa
H0440 Sheng Di Hong Jing Tian圣地红景天 Integripetal rhodiolaRhodiola sacra
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0248 Mi Ying Su Ke蜜罂粟壳 Opium poppyPapaver somniferum
H0085 Jiu Yu Rou酒萸肉 Asiatic cornelian cherryCornus officinalis
H1184 Bai Lian白蔹 Japanese ampelopsisAmpelopsis japonica
H0819 Zhi Zi Jin Gao栀子浸膏 Cape jasmine fruitGardenia jasminoides
H1137 Gui Yuan桂圆 NADimocarpus longan
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0464 Shi Liu Zi石榴子 NAPunica granatum
H1079 Gan Di Huang干地黄 Adhesive rehmannia dried rootRehmannia glutinosa
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0757 Ying Su Ke罂粟壳 Opium poppy pericarpPapaver somniferum
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0179 Lu Xian Cao鹿衔草 Chinese pyrolaPyrola calliantha
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H0858 Zong Lv Pi棕榈皮 Fortune windmillpalmTrachycarpus fortunei
H0421 Shan Zha Qing Gao山楂清膏 Chinese hawthornCrataegus pinnatifida
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H1156 Ai Di Huang矮地黄 RehmanniaeRehmannia glutinosa
H1000 Dong Gua Zi冬瓜子 Chinese waxgourd seedBenincasa hispida
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0634 Xian He Cao仙鹤草 Japanese argimoniaAgrimonia pilosa var. japonica
H0128 Lao Guan Cao老鹳草 Wilford cranesbillGeranium wilfordii
H0453 Shi Di柿蒂 Persimmon persistent calyxDiospyros kaki
H0166 Long Kui龙葵 Black nightshadeSolanum nigrum
H0973 Di Huang Tan地黄炭 RehmanniaeRehmannia glutinosa
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0214 Bei He Huan北合欢 AlbiziaAlbizia julibrissin
H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H0277 Nan Ban Lan Gen南板蓝根 Indigowoad rootBaphicacanthus cusia
H0734 Ye Xia Zhu叶下珠 Common leafflowerPhyllanthus urinaria
H0379 Bian Xu萹蓄 Common knotgrassPolygonum aviculare
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0733 Ye Shan Zha野山楂 nippon bawthornCrataegus pinnatifida
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0408 Bing Lang槟榔 BetenutpalmAreca catechu
H0772 Yue Ji Hua月季花 Chinese roseRosa chinensis
H0068 Jin Ying Zi Rou金樱子肉 Cherokee rose seedRosa laevigata
H0567 Tu Da Huang土大黄 NARumex obtusifolius
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H0705 Yan Hu Lu Ba盐胡芦巴 FenugreekTrigonella foenum-graecum
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0351 Quan Shen拳参 BistortPolygonum bistorta
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0975 Di Mian Cao地绵草 NAEuphorbia humifusa
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0012 Ji Mu Ye Jin Gao继木叶浸膏 NALoropetalum chinense
H0511 Su Mu苏木 Sappan caesalpiniaCaesalpinia sappan
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H1220 Hua Xiang Shu Guo化香树果 NAPlatycarya strobilacea
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0547 Cang Qing Guo藏青果 MyrobalanTerminalia chebula
H0649 Xiang Si Zi相思子 Coralhead plantAbrus precatorius
H0756 Ying Su罂粟 Opium poppyPapaver somniferum
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H0394 Sang Shen Jin Gao桑葚浸膏 MulberryMorus alba
H0473 Shu Di Huang熟地黄 Adhesive rehmannia cocked rootRehmannia glutinosa
H0259 Mo Shi Zi没食子 Aleppo gallQuercus infectoria