Compound Description

ID:   C0327 Common name:   Propranolol
IUPAC:  1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol CAS:  CAS:525-66-6
Chembl ID:   CHEMBL27 Pubchem ID:   CID:4946
Formula:  C16H21NO2 TCM-ID:  TCMC1946
Smiles:  OC(COc1cccc2c1cccc2)CNC(C)C
Alias:

2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-;

1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol;

(±)-Propranolol;

1-(1-Naphthyloxy)-3-(isopropylamino)-2-propanol;

1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol;

1-(Naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol;

1-Isopropylamino-3-naphthalen-1-yloxypropan-2-ol;

3-(Naphth-1-yloxy)-1-(isopropylamino)propan-2-ol;

AY 64043;

Betalong;

DL-Propranolol;

Euprovasin;

Innopran XL;

Propranolol;

Proprasylyt;

Racemic propranolol;

Reducor;

[2-Hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine;

dl-Propranolol;

β-Propranolol
Structure:

Related Targets  (Total: 17)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T92UWJ Beta-2 adrenergic receptorADRB2 P07550
A 10 Reference(s)
T64T6J Beta-1 adrenergic receptorADRB1 P08588
A 7 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
A 2 Reference(s)
T31QEZ 5-hydroxytryptamine receptor 1AHTR1A P08908
A 1 Reference(s)
T11ZYR Cytochrome P450 2D6CYP2D6 P10635
A 1 Reference(s)
T67Q8X Calcium-activated potassium channel subunit beta-1KCNMB1 Q16558
A 1 Reference(s)
T42ZUM NACYP2B7P NA
A 1 Reference(s)
T05WWN CorticoliberinCRH P06850
A 1 Reference(s)
T31VDH Myeloid differentiation primary response protein MyD88MYD88 Q99836
C 1 Reference(s)
T34DZ7 Interleukin-2IL2 P60568
C 1 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
C 1 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
C 2 Reference(s)
T28HOM LeptinLEP P41159
C 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
C 1 Reference(s)
T66A7X Activity-regulated cytoskeleton-associated proteinARC Q7LC44
C 1 Reference(s)
T92HNO High mobility group protein B1HMGB1 P09429
C 1 Reference(s)
T82GHD Kit ligandKITLG P21583
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans