HIT-result

Type	Detail
Target ID	T64T6J
Protein Name	Beta-1 adrenergic receptor
Uniprot ID	P08588
Protein Name Alias	Beta-1 adrenoreceptor; Beta-1 adrenoceptor
Gene ID	153
Gene Symbol	ADRB1
Gene Alias	ADRB1R; B1AR
TTD	T44068: Successful target
Pfam	PF00001
GO	0120162:positive regulation of cold-induced thermogenesis 0002862:negative regulation of inflammatory response to antigenic stimulus 0042596:fear response 0031694:alpha-2A adrenergic receptor binding 0004940:beta1-adrenergic receptor activity 0007186:G protein-coupled receptor signaling pathway 0040015:negative regulation of multicellular organism growth 0043547:positive regulation of GTPase activity 0004939:beta-adrenergic receptor activity 0005085:guanyl-nucleotide exchange factor activity 0031649:heat generation 0030165:PDZ domain binding 0046982:protein heterodimerization activity 0098685:Schaffer collateral - CA1 synapse 0005886:plasma membrane 0004930:G protein-coupled receptor activity 0005769:early endosome 0001997:positive regulation of the force of heart contraction by epinephrine-norepinephrine 0002025:norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure 0005887:integral component of plasma membrane 0050873:brown fat cell differentiation 0099579:G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 0071880:adenylate cyclase-activating adrenergic receptor signaling pathway 0045187:regulation of circadian sleep/wake cycle, sleep 0009409:response to cold 0002024:diet induced thermogenesis 0007190:activation of adenylate cyclase activity 0001996:positive regulation of heart rate by epinephrine-norepinephrine
PDB	2LSQ
Drugbank	DB06726 ; DB01288 ; DB00938 ; DB09068 ; DB01291 ; DB03566 ; DB00243 ; DB00408 ; DB09013 ; DB00555 ; DB01049 ; DB01102 ; DB01297 ; DB00397 ; DB08347 ; DB01359 ; DB13345 ; DB04861 ; DB01193 ; DB00871 ; DB00221 ; DB00335 ; DB00571 ; DB01365 ; DB00195 ; DB00785 ; DB00373 ; DB01001 ; DB08808 ; DB00852 ; DB00368 ; DB01580 ; DB00866 ; DB00598 ; DB00187 ; DB01203 ; DB00127 ; DB01118 ; DB01210 ; DB01182 ; DB00668 ; DB01917 ; DB00182 ; DB06262 ; DB04846 ; DB06216 ; DB00264 ; DB01064 ; DB00540 ; DB11273 ; DB00715 ; DB00841 ; DB04855 ; DB01238 ; DB13781 ; DB11278 ; DB08558 ; DB01407 ; DB01363 ; DB00217 ; DB01295 ; DB00521 ; DB00960 ; DB01364 ; DB09351 ; DB01151 ; DB00983 ; DB11124 ; DB00726 ; DB00612 ; DB00334 ; DB09204 ; DB08807 ; DB00248 ; DB01136 ; DB01214 ; DB00489
KEGG	hsa:153

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0629	Xi Xin	细辛	Siebold wildginger	Asarum sieboldii
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0365	Rou Dou Kou	肉豆蔻	Common nutmeg	Myristica fragrans
H0258	Mo Han Lian	墨旱莲	Yerbadetajo	Eclipta prostrata
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H1077	Bai Hu Jiao	白胡椒	white pepper	Piper nigrum
H1204	Hu Jiao	胡椒	Black pepper	Piper nigrum
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1176	Hei Hu Jiao	黑胡椒	Black pepper	Piper nigrum
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0275	Mu Zei	木贼	Common scouring rush	Equisetum hiemale
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium

Target Description

Related Compounds (Total: 6)

Related Herbs (Total: 20)