HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T23P74	Caspase-9	CASP9	P55211	3 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	5 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	2 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	7 Reference(s)
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	1 Reference(s)
T54G8J	Protein kinase C delta type	PRKCD	Q05655	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	3 Reference(s)
T20IHC	Diacylglycerol O-acyltransferase 1	DGAT1	O75907	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	2 Reference(s)
T16UZ4	Dipeptidyl peptidase 4	DPP4	P27487	1 Reference(s)
T56TXY	Polyunsaturated fatty acid 5-lipoxygenase	ALOX5	P09917	2 Reference(s)
T31U13	Cytochrome P450 2C19	CYP2C19	P33261	1 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	1 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	3 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T11ZYR	Cytochrome P450 2D6	CYP2D6	P10635	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	1 Reference(s)
T54X6V	Intermediate conductance calcium-activated potassium channel protein 4	KCNN4	O15554	1 Reference(s)
T74P7I	G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	1 Reference(s)
T28PHS	Angiotensin-converting enzyme	ACE	P12821	2 Reference(s)
T69CTT	Acetyl-CoA acetyltransferase, mitochondrial	ACAT1	P24752	1 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T61M4P	Nuclear receptor ROR-alpha	RORA	P35398	1 Reference(s)
T77VME	ATP-binding cassette sub-family F member 3	ABCF3	Q9NUQ8	1 Reference(s)
T80XW6	Scavenger receptor class B member 1	SCARB1	Q8WTV0	1 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	2 Reference(s)
T93AZS	NA	ECB2	NA	1 Reference(s)
T38OH4	Caspase-1	CASP1	P29466	1 Reference(s)
T63KO8	NA	MIR33A	NA	1 Reference(s)
T68OIU	CREB-regulated transcription coactivator 1	CRTC1	Q6UUV9	1 Reference(s)
T51IKV	DNA topoisomerase 2-alpha	TOP2A	P11388	1 Reference(s)
T87DEX	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	XDH	P47989	4 Reference(s)
T32R5L	Cyclin-dependent kinase 9	CDK9	P50750	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	1 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	8 Reference(s)
T62UOD	Serine/threonine-protein kinase VRK1	VRK1	Q99986	1 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	1 Reference(s)
T60B3R	Glutathione S-transferase kappa 1	GSTK1	Q9Y2Q3	1 Reference(s)
T67CB6	Transcriptional regulator ERG	ERG	P11308	1 Reference(s)
T39M6J	ATP-binding cassette sub-family C member 2	ABCC2	Q92887	1 Reference(s)
T97FEF	Broad substrate specificity ATP-binding cassette transporter ABCG2	ABCG2	Q9UNQ0	1 Reference(s)
T11NOZ	NA	MIR132	NA	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	1 Reference(s)
T68DAN	Histone deacetylase 9	HDAC9	Q9UKV0	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)
T91AIW	Receptor-type tyrosine-protein kinase FLT3	FLT3	P36888	1 Reference(s)
T25M2J	Anoctamin-1	ANO1	Q5XXA6	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	2 Reference(s)
T29B10	Interleukin-17A	IL17A	Q16552	1 Reference(s)
T38O11	Cyclin-G-associated kinase	GAK	O14976	1 Reference(s)
T77ERW	Protein disulfide-isomerase A3	PDIA3	P30101	1 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	2 Reference(s)
T02GD4	Tumor necrosis factor ligand superfamily member 6	FASLG	P48023	2 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	5 Reference(s)
T97KL5	Microsomal glutathione S-transferase 1	MGST1	P10620	2 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	7 Reference(s)
T81BH5	Sulfotransferase 1A1	SULT1A1	P50225	2 Reference(s)
T32SPJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	P48736	1 Reference(s)
T00CXT	Prostaglandin G/H synthase 1	PTGS1	P23219	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T99XQ3	DNA topoisomerase 1	TOP1	P11387	2 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	5 Reference(s)
T68BGR	Glial fibrillary acidic protein	GFAP	P14136	1 Reference(s)
T46YMA	Ras-related C3 botulinum toxin substrate 1	RAC1	P63000	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	2 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	3 Reference(s)
T93R42	Dipeptidyl peptidase 1	CTSC	P53634	1 Reference(s)
T75ZQD	Myelin proteolipid protein	PLP1	P60201	2 Reference(s)
T67U3B	Translocator protein	TSPO	P30536	4 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	2 Reference(s)
T44AEN	NPC intracellular cholesterol transporter 1	NPC1	O15118	2 Reference(s)
T01E8J	Amyloid-beta precursor protein	APP	P05067	2 Reference(s)
T73S71	Apolipoprotein B-100	APOB	P04114	3 Reference(s)
T50V79	Interleukin-4	IL4	P05112	2 Reference(s)
T13DVU	Conserved oligomeric Golgi complex subunit 2	COG2	Q14746	1 Reference(s)
T37I8W	NA	MIR33B	NA	1 Reference(s)
T63YAO	Caveolin-1	CAV1	Q03135	1 Reference(s)
T56FPY	CD81 antigen	CD81	P60033	1 Reference(s)
T89EW0	Aquaporin-8	AQP8	O94778	1 Reference(s)
T21K0F	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	ATP2A3	Q93084	1 Reference(s)
T92MGC	Phosphatidylcholine:ceramide cholinephosphotransferase 2	SGMS2	Q8NHU3	1 Reference(s)
T81DYL	Cysteine-rich secretory protein 2	CRISP2	P16562	1 Reference(s)
T90K33	ATP-binding cassette sub-family G member 5	ABCG5	Q9H222	2 Reference(s)
T75NEV	Aquaporin-1	AQP1	P29972	1 Reference(s)
T91X8E	Sterol carrier protein 2	SCP2	P22307	1 Reference(s)
T07VO1	Steroid hormone receptor ERR1	ESRRA	P11474	1 Reference(s)
T47RAK	NA	MIR145	NA	1 Reference(s)
T15ZAV	Lymphocyte antigen 96	LY96	Q9Y6Y9	1 Reference(s)
T38WWN	Serum paraoxonase/arylesterase 1	PON1	P27169	1 Reference(s)
T84AR4	Smoothened homolog	SMO	Q99835	1 Reference(s)
T44GAO	55 kDa erythrocyte membrane protein	MPP1	Q00013	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	1 Reference(s)
T08VQQ	Proprotein convertase subtilisin/kexin type 9	PCSK9	Q8NBP7	1 Reference(s)
T75SPS	Fibroblast growth factor 1	FGF1	P05230	1 Reference(s)
T58CPZ	G-protein coupled receptor 55	GPR55	Q9Y2T6	1 Reference(s)
T16CFE	Lysosome-associated membrane glycoprotein 1	LAMP1	P11279	1 Reference(s)
T02GMU	Lysosome-associated membrane glycoprotein 2	LAMP2	P13473	1 Reference(s)
T44X5B	Cholesterol 24-hydroxylase	CYP46A1	Q9Y6A2	2 Reference(s)
T35OPL	Sonic hedgehog protein	SHH	Q15465	1 Reference(s)
T59L1E	Sterol regulatory element-binding protein cleavage-activating protein	SCAP	Q12770	1 Reference(s)
T55TEP	Steroidogenic acute regulatory protein, mitochondrial	STAR	P49675	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	2 Reference(s)
T14LSK	E3 ubiquitin-protein ligase XIAP	XIAP	P98170	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	3 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	3 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	2 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	3 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	1 Reference(s)
T47HTN	Prostaglandin E synthase	PTGES	O14684	1 Reference(s)
T38K2W	Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	2 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T75H3W	Cyclin-dependent kinase 2	CDK2	P24941	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T24LXT	G2/mitotic-specific cyclin-B1	CCNB1	P14635	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	1 Reference(s)
T06PVX	E3 ubiquitin-protein ligase Mdm2	MDM2	Q00987	1 Reference(s)
T92AMR	Hepatocyte growth factor receptor	MET	P08581	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	5 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T37VLU	Interferon gamma	IFNG	P01579	1 Reference(s)
T88B8X	Insulin receptor	INSR	P06213	1 Reference(s)
T68SE0	Solute carrier family 2, facilitated glucose transporter member 4	SLC2A4	P14672	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T60GGR	Serine/threonine-protein kinase TBK1	TBK1	Q9UHD2	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	1 Reference(s)
T01E7W	Aurora kinase B	AURKB	Q96GD4	1 Reference(s)
T77M4W	Adenosine receptor A2a	ADORA2A	P29274	1 Reference(s)
T62Y4H	Protein kinase C epsilon type	PRKCE	Q02156	1 Reference(s)
T35LKG	Adenosine receptor A1	ADORA1	P30542	1 Reference(s)
T45G32	Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	1 Reference(s)
T37BP1	Serine/threonine-protein kinase pim-1	PIM1	P11309	1 Reference(s)
T08B2M	M-phase inducer phosphatase 1	CDC25A	P30304	1 Reference(s)
T33UEM	Lactoperoxidase	LPO	P22079	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T03TJ0	Interleukin-33	IL33	O95760	1 Reference(s)
T40G6B	Prostaglandin reductase 1	PTGR1	Q14914	1 Reference(s)
T31VDH	Myeloid differentiation primary response protein MyD88	MYD88	Q99836	1 Reference(s)
T16A2X	Catalase	CAT	P04040	1 Reference(s)
T07NML	P-selectin	SELP	P16109	1 Reference(s)
T25H22	Protein kinase C beta type	PRKCB	P05771	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T80SD7	Sterol regulatory element-binding protein 2	SREBF2	Q12772	1 Reference(s)
T50MQN	NPC1-like intracellular cholesterol transporter 1	NPC1L1	Q9UHC9	2 Reference(s)
T61DYZ	Phospholipid-transporting ATPase ABCA1	ABCA1	O95477	1 Reference(s)
T94H37	Cadherin-1	CDH1	P12830	1 Reference(s)
T79UHV	Prolow-density lipoprotein receptor-related protein 1	LRP1	Q07954	1 Reference(s)
T47HOW	NA	MIR185	NA	1 Reference(s)
T90IQF	NA	HULC	NA	1 Reference(s)
T86TYE	Dehydrodolichyl diphosphate synthase complex subunit NUS1	NUS1	Q96E22	1 Reference(s)
T26CFB	DNA damage-inducible transcript 3 protein	DDIT3	P35638;P0DPQ6	1 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	1 Reference(s)
T30C1L	Sorting nexin-8	SNX8	Q9Y5X2	1 Reference(s)
T17T4P	NA	MIR122	NA	1 Reference(s)
T79TJS	Caveolin-3	CAV3	P56539	1 Reference(s)
T66IUC	Homeobox protein Nkx-2.5	NKX2-5	P52952	1 Reference(s)
T99EYH	Lipoprotein lipase	LPL	P06858	1 Reference(s)
T95EU5	ATP-binding cassette sub-family G member 8	ABCG8	Q9H221	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	2 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	1 Reference(s)
T68AKE	Zinc fingers and homeoboxes protein 2	ZHX2	Q9Y6X8	1 Reference(s)
T73LPO	Poly [ADP-ribose] polymerase 1	PARP1	P09874	1 Reference(s)
T10K5R	NA	MIR203A	NA	1 Reference(s)
T66WWM	Claudin-2	CLDN2	P57739	2 Reference(s)
T78O6C	Mothers against decapentaplegic homolog 3	SMAD3	P84022	1 Reference(s)
T92HNO	High mobility group protein B1	HMGB1	P09429	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T78IOY	Telomerase reverse transcriptase	TERT	O14746	1 Reference(s)
T41BXR	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	SIRT3	Q9NTG7	1 Reference(s)
T41DXP	Pleiotrophin	PTN	P21246	1 Reference(s)
T62RLH	NA	MIR384	NA	1 Reference(s)
T33KFW	Matrilysin	MMP7	P09237	1 Reference(s)

Herb ID: H0649	Chinese Character: 相思子
English Name: Coralhead plant	Latin Name: Abrus precatorius
Chinese Pin Yin : Xiang Si Zi	TCM-ID: TCMH2278
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: NA

Herb Description

Related Targets (Total: 180)

Related Compounds (Total: 10)