HIT-result

Type	Detail
Target ID	T75SPS
Protein Name	Fibroblast growth factor 1
Uniprot ID	P05230
Protein Name Alias	FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1
Gene ID	2246
Gene Symbol	FGF1
Gene Alias	FGFA
TTD	T18639: Clinical Trial target
Pfam	PF00167
GO	0005634:nucleus 0007275:multicellular organism development 0001759:organ induction 0005938:cell cortex 0030335:positive regulation of cell migration 0005829:cytosol 0030334:regulation of cell migration 0044548:S100 protein binding 1901509:regulation of endothelial tube morphogenesis 0010595:positive regulation of endothelial cell migration 0008284:positive regulation of cell population proliferation 0051897:positive regulation of protein kinase B signaling 0051781:positive regulation of cell division 0009653:anatomical structure morphogenesis 0030324:lung development 0000187:activation of MAPK activity 0032148:activation of protein kinase B activity 0060681:branch elongation involved in ureteric bud branching 0005737:cytoplasm 0008543:fibroblast growth factor receptor signaling pathway 0050679:positive regulation of epithelial cell proliferation 0005615:extracellular space 0030154:cell differentiation 0072163:mesonephric epithelium development 1903672:positive regulation of sprouting angiogenesis 0000165:MAPK cascade 0010628:positive regulation of gene expression 0008201:heparin binding 0001934:positive regulation of protein phosphorylation 0008083:growth factor activity 0045542:positive regulation of cholesterol biosynthetic process 0031012:extracellular matrix 0005730:nucleolus 0005178:integrin binding 2000347:positive regulation of hepatocyte proliferation 1902533:positive regulation of intracellular signal transduction 0005576:extracellular region 0045766:positive regulation of angiogenesis 0005104:fibroblast growth factor receptor binding 0043406:positive regulation of MAP kinase activity 0007165:signal transduction 2000544:regulation of endothelial cell chemotaxis to fibroblast growth factor 0001525:angiogenesis 0005654:nucleoplasm 0034605:cellular response to heat 0042060:wound healing 0045944:positive regulation of transcription by RNA polymerase II 0030544:Hsp70 protein binding 0009887:animal organ morphogenesis
PDB	3FJK ; 3BAH ; 3BAV ; 4J23 ; 3FJI ; 3OJV ; 2AFG ; 1JT5 ; 3UD9 ; 3BA5 ; 3BAG ; 1NZK ; 1DJS ; 1RY7 ; 2ERM ; 3FJ9 ; 1RG8 ; 3CU1 ; 3FJJ ; 3K1X ; 2HW9 ; 3BAQ ; 3B9U ; 3BA4 ; 2AQZ ; 3FJD ; 4QAL ; 3BAU ; 2NTD ; 2HWA ; 3FJB ; 3FJA ; 2Q9X ; 1JT7 ; 2RQ9 ; 1JT4 ; 4Q9G ; 1M16 ; 1K5V ; 3UD7 ; 3CRH ; 2K8R ; 1JT3 ; 2KI4 ; 1DZD ; 3JUT ; 2AXM ; 3O3Q ; 4QC4 ; 4QBV ; 3FJC ; 3FJE ; 3OJM ; 3BB2 ; 1Z4S ; 1JY0 ; 1RML ; 4QO3 ; 1QCT ; 1PZZ ; 1JTC ; 1JQZ ; 3CRI ; 1EVT ; 3UDA ; 1HKN ; 4Q91 ; 1E0O ; 2K4A ; 4YOL ; 1Q04 ; 3FGM ; 2K43 ; 4XKI ; 3HOM ; 2HWM ; 3UD8 ; 2KI6 ; 3CRG ; 3FJH ; 3FJF ; 1K5U ; 1Q03 ; 3OJ2 ; 1YTO ; 3BAD ; 3FJ8 ; 1Z2V ; 4QBC ; 3BA7 ; 2HZ9 ; 1AXM ; 3BAO ; 1DZC ; 4Q9P ; 1P63 ; 3CQA
Drugbank	DB10770 ; DB08238 ; DB10772 ; DB03959 ; DB02264 ; DB00686 ; DB01025 ; DB01942 ; DB04409 ; DB01901 ; DB06589 ; DB01109
KEGG	hsa:2246

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Name: Cholesterol

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Name: Aspirin

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Name: Cholesterol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0607	Wu Wei Zi Jin Chu Wu	五味子浸出物	Five-flavor berry	Schisandra chinensis
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0735	Yi Bei Mu	伊贝母	Siberian fritillary equivalent plant: fritillaria walujewii	Fritillaria pallidiflora
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0605	Wu Wei Zi	五味子	Chinese magnoliavine	Schisandra chinensis
H0838	Zhu Zi Shen	珠子参	Largeleaf japanese ginseng rhizome	Rhizoma panacis majoris
H0648	Xiang Si Teng	相思藤	Coralhead plant vine	Abrus precatorius
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0606	Wu Wei Zi Chun Jin Gao	五味子醇浸膏	Five-flavor berry	Schisandra chinensis
H1226	Huai Shan Yao	淮山药	rhizome of biglcaf yam	Rhizoma dioscoreae
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0287	Nao Yang Hua	闹羊花	Chinese azalea	Rhododendron molle
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H0609	Wu Wei Zi Liu Jin Gao	五味子流浸膏	Five-flavor berry	Schisandra chinensis
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0608	Wu Wei Zi Jin Gao	五味子浸膏	Five-flavor berry	Schisandra chinensis
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0649	Xiang Si Zi	相思子	Coralhead plant	Abrus precatorius
H0476	Can E	蚕蛾	Silkworm	Bombyx mori

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 29)