HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	3 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	5 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T28PHS	Angiotensin-converting enzyme	ACE	P12821	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	2 Reference(s)
T69CTT	Acetyl-CoA acetyltransferase, mitochondrial	ACAT1	P24752	1 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T61M4P	Nuclear receptor ROR-alpha	RORA	P35398	1 Reference(s)
T77VME	ATP-binding cassette sub-family F member 3	ABCF3	Q9NUQ8	1 Reference(s)
T80XW6	Scavenger receptor class B member 1	SCARB1	Q8WTV0	1 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T93AZS	NA	ECB2	NA	1 Reference(s)
T38OH4	Caspase-1	CASP1	P29466	1 Reference(s)
T63KO8	NA	MIR33A	NA	1 Reference(s)
T68OIU	CREB-regulated transcription coactivator 1	CRTC1	Q6UUV9	1 Reference(s)
T11GHO	Transforming protein RhoA	RHOA	P61586	1 Reference(s)
T62FNY	Adenosine receptor A3	ADORA3	P0DMS8	1 Reference(s)
T47DYR	P2Y purinoceptor 1	P2RY1	P47900	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	1 Reference(s)
T98RXH	Focal adhesion kinase 1	PTK2	Q05397	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T75ZQD	Myelin proteolipid protein	PLP1	P60201	2 Reference(s)
T67U3B	Translocator protein	TSPO	P30536	4 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	2 Reference(s)
T44AEN	NPC intracellular cholesterol transporter 1	NPC1	O15118	2 Reference(s)
T01E8J	Amyloid-beta precursor protein	APP	P05067	2 Reference(s)
T73S71	Apolipoprotein B-100	APOB	P04114	3 Reference(s)
T50V79	Interleukin-4	IL4	P05112	1 Reference(s)
T13DVU	Conserved oligomeric Golgi complex subunit 2	COG2	Q14746	1 Reference(s)
T37I8W	NA	MIR33B	NA	1 Reference(s)
T63YAO	Caveolin-1	CAV1	Q03135	1 Reference(s)
T56FPY	CD81 antigen	CD81	P60033	1 Reference(s)
T89EW0	Aquaporin-8	AQP8	O94778	1 Reference(s)
T21K0F	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	ATP2A3	Q93084	1 Reference(s)
T92MGC	Phosphatidylcholine:ceramide cholinephosphotransferase 2	SGMS2	Q8NHU3	1 Reference(s)
T81DYL	Cysteine-rich secretory protein 2	CRISP2	P16562	1 Reference(s)
T90K33	ATP-binding cassette sub-family G member 5	ABCG5	Q9H222	2 Reference(s)
T75NEV	Aquaporin-1	AQP1	P29972	1 Reference(s)
T91X8E	Sterol carrier protein 2	SCP2	P22307	1 Reference(s)
T07VO1	Steroid hormone receptor ERR1	ESRRA	P11474	1 Reference(s)
T47RAK	NA	MIR145	NA	1 Reference(s)
T15ZAV	Lymphocyte antigen 96	LY96	Q9Y6Y9	1 Reference(s)
T38WWN	Serum paraoxonase/arylesterase 1	PON1	P27169	1 Reference(s)
T84AR4	Smoothened homolog	SMO	Q99835	1 Reference(s)
T44GAO	55 kDa erythrocyte membrane protein	MPP1	Q00013	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	1 Reference(s)
T08VQQ	Proprotein convertase subtilisin/kexin type 9	PCSK9	Q8NBP7	1 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	1 Reference(s)
T75SPS	Fibroblast growth factor 1	FGF1	P05230	1 Reference(s)
T58CPZ	G-protein coupled receptor 55	GPR55	Q9Y2T6	1 Reference(s)
T16CFE	Lysosome-associated membrane glycoprotein 1	LAMP1	P11279	1 Reference(s)
T02GMU	Lysosome-associated membrane glycoprotein 2	LAMP2	P13473	1 Reference(s)
T44X5B	Cholesterol 24-hydroxylase	CYP46A1	Q9Y6A2	2 Reference(s)
T35OPL	Sonic hedgehog protein	SHH	Q15465	1 Reference(s)
T59L1E	Sterol regulatory element-binding protein cleavage-activating protein	SCAP	Q12770	1 Reference(s)
T55TEP	Steroidogenic acute regulatory protein, mitochondrial	STAR	P49675	1 Reference(s)
T95Y0K	Sphingosine kinase 1	SPHK1	Q9NYA1	1 Reference(s)
T14R01	Cell death activator CIDE-B	CIDEB	Q9UHD4	1 Reference(s)
T11TKN	Leucine-rich repeat serine/threonine-protein kinase 2	LRRK2	Q5S007	1 Reference(s)
T05V67	Toll-like receptor 8	TLR8	Q9NR97	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T80SD7	Sterol regulatory element-binding protein 2	SREBF2	Q12772	1 Reference(s)
T50MQN	NPC1-like intracellular cholesterol transporter 1	NPC1L1	Q9UHC9	2 Reference(s)
T61DYZ	Phospholipid-transporting ATPase ABCA1	ABCA1	O95477	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	1 Reference(s)
T94H37	Cadherin-1	CDH1	P12830	1 Reference(s)
T79UHV	Prolow-density lipoprotein receptor-related protein 1	LRP1	Q07954	1 Reference(s)
T25H22	Protein kinase C beta type	PRKCB	P05771	1 Reference(s)
T47HOW	NA	MIR185	NA	1 Reference(s)
T90IQF	NA	HULC	NA	1 Reference(s)
T86TYE	Dehydrodolichyl diphosphate synthase complex subunit NUS1	NUS1	Q96E22	1 Reference(s)
T26CFB	DNA damage-inducible transcript 3 protein	DDIT3	P35638;P0DPQ6	1 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	1 Reference(s)
T30C1L	Sorting nexin-8	SNX8	Q9Y5X2	1 Reference(s)
T17T4P	NA	MIR122	NA	1 Reference(s)
T79TJS	Caveolin-3	CAV3	P56539	1 Reference(s)
T66IUC	Homeobox protein Nkx-2.5	NKX2-5	P52952	1 Reference(s)
T99EYH	Lipoprotein lipase	LPL	P06858	1 Reference(s)
T95EU5	ATP-binding cassette sub-family G member 8	ABCG8	Q9H221	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	1 Reference(s)

Herb ID: H0735	Chinese Character: 伊贝母
English Name: Siberian fritillary equivalent plant: fritillaria walujewii	Latin Name: Fritillaria pallidiflora
Chinese Pin Yin : Yi Bei Mu	TCM-ID: TCMH2469
Therapeutic Function in Chinese : 化痰止咳平喘	Therapeutic Function in English: For desolving phlegm, stopping cougth, and soothing breathing
Herb Function: Remove heat from the lung, resolve phlegm, and reduce nodules

Herb Description

Related Targets (Total: 87)

Related Compounds (Total: 6)