Herb ID: H0735 | Chinese Character: 伊贝母 |
English Name: Siberian fritillary equivalent plant: fritillaria walujewii | Latin Name: Fritillaria pallidiflora |
Chinese Pin Yin : Yi Bei Mu | TCM-ID: TCMH2469 |
Therapeutic Function in Chinese : 化痰止咳平喘 | Therapeutic Function in English: For desolving phlegm, stopping cougth, and soothing breathing |
Herb Function: Remove heat from the lung, resolve phlegm, and reduce nodules |
Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
---|---|---|---|---|
T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
T01QLH | Estrogen receptor | ESR1 |
P03372 |
1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
3 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
5 Reference(s) |
T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
2 Reference(s) |
T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
T69CTT | Acetyl-CoA acetyltransferase, mitochondrial | ACAT1 |
P24752 |
1 Reference(s) |
T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
T61M4P | Nuclear receptor ROR-alpha | RORA |
P35398 |
1 Reference(s) |
T77VME | ATP-binding cassette sub-family F member 3 | ABCF3 |
Q9NUQ8 |
1 Reference(s) |
T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
1 Reference(s) |
T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
T93AZS | NA | ECB2 |
NA |
1 Reference(s) |
T38OH4 | Caspase-1 | CASP1 |
P29466 |
1 Reference(s) |
T63KO8 | NA | MIR33A |
NA |
1 Reference(s) |
T68OIU | CREB-regulated transcription coactivator 1 | CRTC1 |
Q6UUV9 |
1 Reference(s) |
T11GHO | Transforming protein RhoA | RHOA |
P61586 |
1 Reference(s) |
T62FNY | Adenosine receptor A3 | ADORA3 |
P0DMS8 |
1 Reference(s) |
T47DYR | P2Y purinoceptor 1 | P2RY1 |
P47900 |
1 Reference(s) |
T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
1 Reference(s) |
T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
T75ZQD | Myelin proteolipid protein | PLP1 |
P60201 |
2 Reference(s) |
T67U3B | Translocator protein | TSPO |
P30536 |
4 Reference(s) |
T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
2 Reference(s) |
T44AEN | NPC intracellular cholesterol transporter 1 | NPC1 |
O15118 |
2 Reference(s) |
T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
2 Reference(s) |
T73S71 | Apolipoprotein B-100 | APOB |
P04114 |
3 Reference(s) |
T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
T13DVU | Conserved oligomeric Golgi complex subunit 2 | COG2 |
Q14746 |
1 Reference(s) |
T37I8W | NA | MIR33B |
NA |
1 Reference(s) |
T63YAO | Caveolin-1 | CAV1 |
Q03135 |
1 Reference(s) |
T56FPY | CD81 antigen | CD81 |
P60033 |
1 Reference(s) |
T89EW0 | Aquaporin-8 | AQP8 |
O94778 |
1 Reference(s) |
T21K0F | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | ATP2A3 |
Q93084 |
1 Reference(s) |
T92MGC | Phosphatidylcholine:ceramide cholinephosphotransferase 2 | SGMS2 |
Q8NHU3 |
1 Reference(s) |
T81DYL | Cysteine-rich secretory protein 2 | CRISP2 |
P16562 |
1 Reference(s) |
T90K33 | ATP-binding cassette sub-family G member 5 | ABCG5 |
Q9H222 |
2 Reference(s) |
T75NEV | Aquaporin-1 | AQP1 |
P29972 |
1 Reference(s) |
T91X8E | Sterol carrier protein 2 | SCP2 |
P22307 |
1 Reference(s) |
T07VO1 | Steroid hormone receptor ERR1 | ESRRA |
P11474 |
1 Reference(s) |
T47RAK | NA | MIR145 |
NA |
1 Reference(s) |
T15ZAV | Lymphocyte antigen 96 | LY96 |
Q9Y6Y9 |
1 Reference(s) |
T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
T84AR4 | Smoothened homolog | SMO |
Q99835 |
1 Reference(s) |
T44GAO | 55 kDa erythrocyte membrane protein | MPP1 |
Q00013 |
1 Reference(s) |
T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
1 Reference(s) |
T08VQQ | Proprotein convertase subtilisin/kexin type 9 | PCSK9 |
Q8NBP7 |
1 Reference(s) |
T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
T75SPS | Fibroblast growth factor 1 | FGF1 |
P05230 |
1 Reference(s) |
T58CPZ | G-protein coupled receptor 55 | GPR55 |
Q9Y2T6 |
1 Reference(s) |
T16CFE | Lysosome-associated membrane glycoprotein 1 | LAMP1 |
P11279 |
1 Reference(s) |
T02GMU | Lysosome-associated membrane glycoprotein 2 | LAMP2 |
P13473 |
1 Reference(s) |
T44X5B | Cholesterol 24-hydroxylase | CYP46A1 |
Q9Y6A2 |
2 Reference(s) |
T35OPL | Sonic hedgehog protein | SHH |
Q15465 |
1 Reference(s) |
T59L1E | Sterol regulatory element-binding protein cleavage-activating protein | SCAP |
Q12770 |
1 Reference(s) |
T55TEP | Steroidogenic acute regulatory protein, mitochondrial | STAR |
P49675 |
1 Reference(s) |
T95Y0K | Sphingosine kinase 1 | SPHK1 |
Q9NYA1 |
1 Reference(s) |
T14R01 | Cell death activator CIDE-B | CIDEB |
Q9UHD4 |
1 Reference(s) |
T11TKN | Leucine-rich repeat serine/threonine-protein kinase 2 | LRRK2 |
Q5S007 |
1 Reference(s) |
T05V67 | Toll-like receptor 8 | TLR8 |
Q9NR97 |
1 Reference(s) |
T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
T80SD7 | Sterol regulatory element-binding protein 2 | SREBF2 |
Q12772 |
1 Reference(s) |
T50MQN | NPC1-like intracellular cholesterol transporter 1 | NPC1L1 |
Q9UHC9 |
2 Reference(s) |
T61DYZ | Phospholipid-transporting ATPase ABCA1 | ABCA1 |
O95477 |
1 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
1 Reference(s) |
T94H37 | Cadherin-1 | CDH1 |
P12830 |
1 Reference(s) |
T79UHV | Prolow-density lipoprotein receptor-related protein 1 | LRP1 |
Q07954 |
1 Reference(s) |
T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
1 Reference(s) |
T47HOW | NA | MIR185 |
NA |
1 Reference(s) |
T90IQF | NA | HULC |
NA |
1 Reference(s) |
T86TYE | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | NUS1 |
Q96E22 |
1 Reference(s) |
T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
1 Reference(s) |
T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
T30C1L | Sorting nexin-8 | SNX8 |
Q9Y5X2 |
1 Reference(s) |
T17T4P | NA | MIR122 |
NA |
1 Reference(s) |
T79TJS | Caveolin-3 | CAV3 |
P56539 |
1 Reference(s) |
T66IUC | Homeobox protein Nkx-2.5 | NKX2-5 |
P52952 |
1 Reference(s) |
T99EYH | Lipoprotein lipase | LPL |
P06858 |
1 Reference(s) |
T95EU5 | ATP-binding cassette sub-family G member 8 | ABCG8 |
Q9H221 |
1 Reference(s) |
T49PL1 | Low-density lipoprotein receptor | LDLR |
P01130 |
1 Reference(s) |