Target Description

Type Detail
Target ID T11GHO
Protein Name Transforming protein RhoA
Uniprot ID P61586
Protein Name Alias EC 3.6.5.2;  Rho cDNA clone 12;  h12
Gene ID 387
Gene Symbol RHOA
Gene Alias ARH12;  ARHA;  RHO12
TTD T96736: Discontinued target
Pfam PF00071
GO
0045666:positive regulation of neuron differentiation

0008360:regulation of cell shape

0101003:ficolin-1-rich granule membrane

0016579:protein deubiquitination

0050771:negative regulation of axonogenesis

0007186:G protein-coupled receptor signaling pathway

0031410:cytoplasmic vesicle

0010812:negative regulation of cell-substrate adhesion

0005925:focal adhesion

0036089:cleavage furrow formation

0045792:negative regulation of cell size

0033688:regulation of osteoblast proliferation

0098978:glutamatergic synapse

0043542:endothelial cell migration

1904996:positive regulation of leukocyte adhesion to vascular endothelial cell

2000406:positive regulation of T cell migration

0050772:positive regulation of axonogenesis

0007179:transforming growth factor beta receptor signaling pathway

0060071:Wnt signaling pathway, planar cell polarity pathway

0031234:extrinsic component of cytoplasmic side of plasma membrane

0031982:vesicle

0031122:cytoplasmic microtubule organization

0030667:secretory granule membrane

0005856:cytoskeleton

0051056:regulation of small GTPase mediated signal transduction

0016477:cell migration

0032956:regulation of actin cytoskeleton organization

1903673:mitotic cleavage furrow formation

0061383:trabecula morphogenesis

0030865:cortical cytoskeleton organization

0007266:Rho protein signal transduction

0017022:myosin binding

0098794:postsynapse

0071345:cellular response to cytokine stimulus

0038027:apolipoprotein A-I-mediated signaling pathway

1905274:regulation of modification of postsynaptic actin cytoskeleton

1990869:cellular response to chemokine

0071222:cellular response to lipopolysaccharide

0043931:ossification involved in bone maturation

0044319:wound healing, spreading of cells

0032467:positive regulation of cytokinesis

0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling

0043197:dendritic spine

0060193:positive regulation of lipase activity

0030496:midbody

0032154:cleavage furrow

0030054:cell junction

0051496:positive regulation of stress fiber assembly

0048010:vascular endothelial growth factor receptor signaling pathway

0005886:plasma membrane

0005768:endosome

0043296:apical junction complex

0019901:protein kinase binding

0034329:cell junction assembly

0034446:substrate adhesion-dependent cell spreading

0007163:establishment or maintenance of cell polarity

0021762:substantia nigra development

0030334:regulation of cell migration

0050919:negative chemotaxis

0070062:extracellular exosome

1902766:skeletal muscle satellite cell migration

0005789:endoplasmic reticulum membrane

1901224:positive regulation of NIK/NF-kappaB signaling

0090307:mitotic spindle assembly

0071902:positive regulation of protein serine/threonine kinase activity

0031532:actin cytoskeleton reorganization

0051893:regulation of focal adhesion assembly

0030036:actin cytoskeleton organization

0005829:cytosol

0097498:endothelial tube lumen extension

0035385:Roundabout signaling pathway

0043149:stress fiber assembly

2000145:regulation of cell motility

0090051:negative regulation of cell migration involved in sprouting angiogenesis

0005938:cell cortex

0042995:cell projection

0045198:establishment of epithelial cell apical/basal polarity

0043312:neutrophil degranulation

0043297:apical junction assembly

0048013:ephrin receptor signaling pathway

0048015:phosphatidylinositol-mediated signaling

0007015:actin filament organization

0005525:GTP binding

0043231:intracellular membrane-bounded organelle

0016032:viral process

0071944:cell periphery

0003924:GTPase activity

0030027:lamellipodium

PDB 5C2K ; 1CC0 ; 3KZ1 ; 6KX3 ; 6V6V ; 1X86 ; 5C4M ; 4XSH ; 6BCA ; 6KX2 ; 1CXZ ; 2RGN ; 5JCP ; 5HPY ; 5A0F ; 3LW8 ; 6BCB ; 1XCG ; 4XOI ; 5JHH ; 5ZHX ; 3LXR ; 5IRC ; 3MSX ; 6BC0 ; 6V6M ; 6V6U ; 1TX4 ; 5BWM ; 5JHG ; 1DPF ; 6R3V ; 3T06 ; 1LB1 ; 4D0N ; 5EZ6 ; 4XSG ; 1S1C ; 4XH9 ; 3LWN ; 1A2B ; 5M70 ; 1FTN ; 1OW3 ; 5FR1 ; 5FR2 ; 1KMQ ; 5M6X
Drugbank DB04315
KEGG hsa:387

Related Compounds  (Total: 6)

Go to browser
C0055
Name: Estradiol
Go to browser
C0113
Name: Guanine
Go to browser
C0590
Name: Α-Elemene,Β-Elemene
Go to browser
C0610
Name: Butylphthalide
Go to browser
C0867
Name: Alcohol


Related Herbs  (Total: 80)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0638 Xiang Bei象贝 FritillariaFritillaria thunbergii
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H0077 Jiu EthanolVinum
H0938 Da Suan大蒜 GarlicAllium sativum
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0843 Zi Bei Mu紫贝母 NAFritillaria unibracteata
H0892 Chuan Xiong川芎 cnidium officinaleCnidium officinale
H0357 Ren Shen人参 GinsengPanax ginseng
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1007 Dou You豆油 Soybean oilGlycine max
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0278 Nan Ban Lan Gen Jin Gao Fen南板蓝根浸膏粉 Indigowoad rootBaphicacanthus cusia
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0405 Shan Dou Gen山豆根 Tonkin sophora rootSophora subprostrata
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0735 Yi Bei Mu伊贝母 Siberian fritillary equivalent plant: fritillaria walujewiiFritillaria pallidiflora
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H0416 Shan Shen山参 NAPanax ginseng
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0277 Nan Ban Lan Gen南板蓝根 Indigowoad rootBaphicacanthus cusia
H0026 Jiang Soybean pasteGlycine max
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H1247 Huang Qi黄芪 Membranous milkvetchAstragalus membranaceus
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0855 Chuan Bei Mu川贝母 Fritillaria unibracteataFritillaria cirrhosa
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0897 Chuan Lian川楝 ChinaberryMelia azedarach
H0017 Ji Xue Teng鸡血藤 Suberect spatholobus stemSpatholobus suberectus
H1021 E Da Xia莪大夏 NAOxytropis falcata
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0705 Yan Hu Lu Ba盐胡芦巴 FenugreekTrigonella foenum-graecum
H0859 Chuan Bei Mu Liu Jin Gao川贝母流浸膏 Fritillaria unibracteataFritillaria cirrhosa
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H1250 Huang Qi Ti Qu Ye黄芪提取液 Membranous milkvetchAstragalus membranaceus
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0018 Ji Xue Teng Gan Gao鸡血藤干膏 Suberect spatholobus stemSpatholobus suberectus
H0430 She Chuang Zi蛇床子 Common cnidiumCnidium monnieri
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0019 Ji Xue Teng Gao鸡血藤膏 Suberect spatholobus stemSpatholobus suberectus
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H0981 Dian Ji Xue Teng Gao Fen滇鸡血藤膏粉 Suberect spatholobus stemSpatholobus suberectus
H0311 Ping Bei Mu平贝母 Ussuri fritillaryFritillaria ussuriensis
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H1249 Huang Qi Jin Gao黄芪浸膏 Membranous milkvetchAstragalus membranaceus
H1248 Huang Qi Gan Jin Gao黄芪干浸膏 Membranous milkvetchAstragalus membranaceus
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis