Compound Description
Related Targets (Total: 135)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
A | 2 Reference(s) |
| T37WU9 | Sodium/hydrogen exchanger 10 | SLC9C1 |
Q4G0N8 |
A | 1 Reference(s) |
| T59DDI | Liver carboxylesterase 1 | CES1 |
P23141 |
A | 2 Reference(s) |
| T68CKY | Tyrosine-protein kinase Fyn | FYN |
P06241 |
A | 2 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
A | 3 Reference(s) |
| T68OIU | CREB-regulated transcription coactivator 1 | CRTC1 |
Q6UUV9 |
A | 1 Reference(s) |
| T32OC4 | Aldehyde dehydrogenase, mitochondrial | ALDH2 |
P05091 |
A | 5 Reference(s) |
| T76GLY | Eukaryotic translation initiation factor 4B | EIF4B |
P23588 |
A | 1 Reference(s) |
| T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
A | 1 Reference(s) |
| T87UKX | Glucose-6-phosphate 1-dehydrogenase | G6PD |
P11413 |
A | 1 Reference(s) |
| T19CUN | Prothrombin | F2 |
P00734 |
A | 1 Reference(s) |
| T51MX9 | Thiamine transporter 1 | SLC19A2 |
O60779 |
A | 1 Reference(s) |
| T38OH4 | Caspase-1 | CASP1 |
P29466 |
A | 1 Reference(s) |
| T87JTM | Sialin | SLC17A5 |
Q9NRA2 |
A | 1 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
A | 2 Reference(s) |
| T13QI6 | Aldo-keto reductase family 1 member A1 | AKR1A1 |
P14550 |
A | 1 Reference(s) |
| T67MQU | Antileukoproteinase | SLPI |
P03973 |
A | 1 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
A | 1 Reference(s) |
| T16MRU | NACHT, LRR and PYD domains-containing protein 3 | NLRP3 |
Q96P20 |
A | 1 Reference(s) |
| T18RS6 | Glutamate receptor ionotropic, NMDA 2B | GRIN2B |
Q13224 |
A | 2 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
A | 1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
A | 2 Reference(s) |
| T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
A | 2 Reference(s) |
| T71PEL | Excitatory amino acid transporter 2 | SLC1A2 |
P43004 |
A | 1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
A | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
A | 3 Reference(s) |
| T40NB1 | Ribosomal protein S6 kinase beta-1 | RPS6KB1 |
P23443 |
A | 1 Reference(s) |
| T11GHO | Transforming protein RhoA | RHOA |
P61586 |
A | 1 Reference(s) |
| T30KQB | Alanine aminotransferase 1 | GPT |
P24298 |
A | 1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
A | 1 Reference(s) |
| T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
B | 1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
B | 2 Reference(s) |
| T62Y4H | Protein kinase C epsilon type | PRKCE |
Q02156 |
B | 1 Reference(s) |
| T02HZD | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | JMJD6 |
Q6NYC1 |
B | 1 Reference(s) |
| T72QH0 | Eukaryotic translation initiation factor 4E-binding protein 1 | EIF4EBP1 |
Q13541 |
B | 1 Reference(s) |
| T70CEJ | Protein unc-13 homolog A | UNC13A |
Q9UPW8 |
B | 1 Reference(s) |
| T22BYF | Transcription factor IIIB 90 kDa subunit | BRF1 |
Q92994 |
C | 5 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
C | 1 Reference(s) |
| T55A2Y | Glucose-6-phosphate isomerase | GPI |
P06744 |
C | 1 Reference(s) |
| T03R4V | Alpha-2-HS-glycoprotein | AHSG |
P02765 |
C | 1 Reference(s) |
| T58CAO | Alpha-synuclein | SNCA |
P37840 |
C | 1 Reference(s) |
| T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B |
O00300 |
C | 1 Reference(s) |
| T03G09 | Tumor necrosis factor ligand superfamily member 11 | TNFSF11 |
O14788 |
C | 1 Reference(s) |
| T60KU1 | Protein cereblon | CRBN |
Q96SW2 |
C | 1 Reference(s) |
| T98SBW | Interleukin-6 receptor subunit alpha | IL6R |
P08887 |
C | 1 Reference(s) |
| T33BVS | Krueppel-like factor 11 | KLF11 |
O14901 |
C | 1 Reference(s) |
| T17TKM | Melanocortin receptor 4 | MC4R |
P32245 |
C | 1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
C | 1 Reference(s) |
| T08JAV | Phosphatidate phosphatase LPIN1 | LPIN1 |
Q14693 |
C | 2 Reference(s) |
| T74SS7 | Glutamate receptor ionotropic, NMDA 2A | GRIN2A |
Q12879 |
C | 1 Reference(s) |
| T17E49 | Cannabinoid receptor 1 | CNR1 |
P21554 |
C | 1 Reference(s) |
| T43WIP | Cystine/glutamate transporter | SLC7A11 |
Q9UPY5 |
C | 1 Reference(s) |
| T25YP8 | Aquaporin-4 | AQP4 |
P55087 |
C | 1 Reference(s) |
| T08W1L | Tumor necrosis factor receptor superfamily member 16 | NGFR |
P08138 |
C | 1 Reference(s) |
| T17AMT | NA | MIR34A |
NA |
C | 2 Reference(s) |
| T94RQ2 | E3 ubiquitin-protein ligase SIAH1 | SIAH1 |
Q8IUQ4 |
C | 1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
C | 1 Reference(s) |
| T90XYZ | C-reactive protein | CRP |
P02741 |
C | 2 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
C | 3 Reference(s) |
| T67OMA | Ryanodine receptor 2 | RYR2 |
Q92736 |
C | 1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
C | 1 Reference(s) |
| T89GCM | Inward rectifier potassium channel 2 | KCNJ2 |
P63252 |
C | 1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
C | 1 Reference(s) |
| T63EMC | Interleukin-18 | IL18 |
Q14116 |
C | 1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
C | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
C | 1 Reference(s) |
| T54RPK | Dihydropyrimidinase-related protein 2 | DPYSL2 |
Q16555 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
| T18UDY | Synapsin-1 | SYN1 |
P17600 |
C | 1 Reference(s) |
| T88H0Y | Synapsin-2 | SYN2 |
Q92777 |
C | 1 Reference(s) |
| T17LB4 | High affinity immunoglobulin gamma Fc receptor I | FCGR1A |
P12314 |
C | 1 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
C | 1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
C | 1 Reference(s) |
| T78EMM | Nuclear pore glycoprotein p62 | NUP62 |
P37198 |
C | 1 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
C | 1 Reference(s) |
| T86YQL | Prolactin | PRL |
P01236 |
C | 1 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
C | 1 Reference(s) |
| T15P3B | Transient receptor potential cation channel subfamily V member 2 | TRPV2 |
Q9Y5S1 |
C | 1 Reference(s) |
| T70KPE | Transient receptor potential cation channel subfamily V member 3 | TRPV3 |
Q8NET8 |
C | 1 Reference(s) |
| T40EUL | Transient receptor potential cation channel subfamily V member 4 | TRPV4 |
Q9HBA0 |
C | 1 Reference(s) |
| T40YVZ | Multiple PDZ domain protein | MPDZ |
O75970 |
C | 1 Reference(s) |
| T24LWC | Sodium-dependent dopamine transporter | SLC6A3 |
Q01959 |
C | 1 Reference(s) |
| T39NFM | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | DYRK1A |
Q13627 |
C | 1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
C | 1 Reference(s) |
| T85NQ0 | NA | MALAT1 |
NA |
C | 1 Reference(s) |
| T99NM4 | Methionine synthase | MTR |
Q99707 |
C | 1 Reference(s) |
| T08VQQ | Proprotein convertase subtilisin/kexin type 9 | PCSK9 |
Q8NBP7 |
C | 1 Reference(s) |
| T39XCH | NA | MIR411 |
NA |
C | 1 Reference(s) |
| T63V6Q | Cocaine- and amphetamine-regulated transcript protein | CARTPT |
Q16568 |
C | 1 Reference(s) |
| T22H7B | Neuronal acetylcholine receptor subunit alpha-4 | CHRNA4 |
P43681 |
C | 1 Reference(s) |
| T29JA7 | P2X purinoceptor 4 | P2RX4 |
Q99571 |
C | 1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
C | 2 Reference(s) |
| T36RGT | Protein phosphatase 1 regulatory subunit 1B | PPP1R1B |
Q9UD71 |
C | 1 Reference(s) |
| T51YUR | Dihydropyrimidine dehydrogenase [NADP(+)] | DPYD |
Q12882 |
C | 1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
C | 1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
C | 1 Reference(s) |
| T95M9K | Vesicle-associated membrane protein 2 | VAMP2 |
P63027 |
C | 1 Reference(s) |
| T28BLO | Cyclic AMP-responsive element-binding protein 3-like protein 3 | CREB3L3 |
Q68CJ9 |
C | 1 Reference(s) |
| T55EIL | Homeobox protein OTX2 | OTX2 |
P32243 |
C | 1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
C | 1 Reference(s) |
| T93QP3 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABRA1 |
P14867 |
C | 1 Reference(s) |
| T68M1D | Histone deacetylase 2 | HDAC2 |
Q92769 |
C | 1 Reference(s) |
| T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
C | 1 Reference(s) |
| T11FH6 | Phosphatidylinositol 3-kinase regulatory subunit alpha | PIK3R1 |
P27986 |
C | 1 Reference(s) |
| T33F8F | Protein YIF1B | YIF1B |
Q5BJH7 |
C | 1 Reference(s) |
| T86WBI | Stromal interaction molecule 1 | STIM1 |
Q13586 |
C | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
C | 1 Reference(s) |
| T47G3X | Glucocorticoid receptor | NR3C1 |
P04150 |
C | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
| T34X07 | CCAAT/enhancer-binding protein alpha | CEBPA |
P49715 |
C | 1 Reference(s) |
| T40JZG | GPI-anchor transamidase | PIGK |
Q92643 |
C | 1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
C | 1 Reference(s) |
| T19RMS | Neurogenin-2 | NEUROG2 |
Q9H2A3 |
C | 1 Reference(s) |
| T22ZML | Achaete-scute homolog 1 | ASCL1 |
P50553 |
C | 1 Reference(s) |
| T68BGR | Glial fibrillary acidic protein | GFAP |
P14136 |
C | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T06MXL | Neprilysin | MME |
P08473 |
C | 1 Reference(s) |
| T37SV3 | Occludin | OCLN |
Q16625 |
C | 1 Reference(s) |
| T76WHR | Macrophage metalloelastase | MMP12 |
P39900 |
C | 1 Reference(s) |
| T60UPF | Parvalbumin alpha | PVALB |
P20472 |
C | 1 Reference(s) |
| T41I9Y | Junctional adhesion molecule A | F11R |
Q9Y624 |
C | 1 Reference(s) |
| T56QUH | Immunoglobulin-binding protein 1 | IGBP1 |
P78318 |
C | 1 Reference(s) |
| T10OIU | Erythropoietin | EPO |
P01588 |
C | 1 Reference(s) |
| T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
C | 1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
C | 1 Reference(s) |
| T70VMI | Nitric oxide synthase, brain | NOS1 |
P29475 |
C | 1 Reference(s) |
| T58D39 | Osteocalcin | BGLAP |
P02818 |
C | 1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
C | 1 Reference(s) |
| T64E3A | Aminopeptidase N | ANPEP |
P15144 |
C | 1 Reference(s) |
| T90ZKN | Cathepsin B | CTSB |
P07858 |
C | 1 Reference(s) |
| T32IXS | Integrin alpha-M | ITGAM |
P11215 |
C | 1 Reference(s) |
| T82D6U | Ubiquitin-like protein ATG12 | ATG12 |
O94817 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 12)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0522 | Tai Zi Shen | 太子参 | Heterophylly falsestarwort root | Radix pseudostellariae |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
Ckey description of the interaction between compound and target