HIT-result

Target Description

Type	Detail
Target ID	T17TKM
Protein Name	Melanocortin receptor 4
Uniprot ID	P32245
Protein Name Alias	MC4-R
Gene ID	4160
Gene Symbol	MC4R
Gene Alias	NA
TTD	T72458: Successful target
Pfam	PF00001
GO	0016021:integral component of membrane 0031625:ubiquitin protein ligase binding 0045780:positive regulation of bone resorption 0007631:feeding behavior 0002862:negative regulation of inflammatory response to antigenic stimulus 0006112:energy reserve metabolic process 0007186:G protein-coupled receptor signaling pathway 0004977:melanocortin receptor activity 0017046:peptide hormone binding 0005886:plasma membrane 0005737:cytoplasm 0004930:G protein-coupled receptor activity 0042923:neuropeptide binding 0004980:melanocyte-stimulating hormone receptor activity 0007188:adenylate cyclase-modulating G protein-coupled receptor signaling pathway 2000821:regulation of grooming behavior 0005634:nucleus 0002024:diet induced thermogenesis 0019222:regulation of metabolic process 2000252:negative regulation of feeding behavior 0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway
PDB	2IQP ; 2IQV ; 2IQR ; 2IQW ; 2IQU ; 6W25 ; 2IQS
Drugbank	DB11700 ; DB11653
KEGG	hsa:4160

Type

Detail

Target ID

T17TKM

Protein Name

Melanocortin receptor 4

Uniprot ID

P32245

Protein Name Alias

MC4-R

Gene ID

4160

Gene Symbol

MC4R

Gene Alias

TTD

T72458: Successful target

Pfam

PF00001

0016021:integral component of membrane

0031625:ubiquitin protein ligase binding

0045780:positive regulation of bone resorption

0007631:feeding behavior

0002862:negative regulation of inflammatory response to antigenic stimulus

0006112:energy reserve metabolic process

0007186:G protein-coupled receptor signaling pathway

0004977:melanocortin receptor activity

0017046:peptide hormone binding

0005886:plasma membrane

0005737:cytoplasm

0004930:G protein-coupled receptor activity

0042923:neuropeptide binding

0004980:melanocyte-stimulating hormone receptor activity

0007188:adenylate cyclase-modulating G protein-coupled receptor signaling pathway

2000821:regulation of grooming behavior

0005634:nucleus

0002024:diet induced thermogenesis

0019222:regulation of metabolic process

2000252:negative regulation of feeding behavior

0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

PDB

2IQP ; 2IQV ; 2IQR ; 2IQW ; 2IQU ; 6W25 ; 2IQS

Drugbank

DB11700 ; DB11653

KEGG

hsa:4160

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0416	Shan Shen	山参	NA	Panax ginseng
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 15)