HIT-result

Type	Detail
Target ID	T41I9Y
Protein Name	Junctional adhesion molecule A
Uniprot ID	Q9Y624
Protein Name Alias	JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD antigen CD321
Gene ID	50848
Gene Symbol	F11R
Gene Alias	JAM1; JCAM
TTD	T15438: Research target
Pfam	PF07686
GO	0070062:extracellular exosome 0005178:integrin binding 0032991:protein-containing complex 0016021:integral component of membrane 0045777:positive regulation of blood pressure 0031032:actomyosin structure organization 1903142:positive regulation of establishment of endothelial barrier 0008360:regulation of cell shape 0032956:regulation of actin cytoskeleton organization 0050900:leukocyte migration 0035683:memory T cell extravasation 0071260:cellular response to mechanical stimulus 0051497:negative regulation of stress fiber assembly 0090557:establishment of endothelial intestinal barrier 0043547:positive regulation of GTPase activity 0030054:cell junction 2000249:regulation of actin cytoskeleton reorganization 0001618:virus receptor activity 0030165:PDZ domain binding 0007159:leukocyte cell-cell adhesion 0001817:regulation of cytokine production 0050892:intestinal absorption 0035025:positive regulation of Rho protein signal transduction 0005886:plasma membrane 0005911:cell-cell junction 0009314:response to radiation 0036057:slit diaphragm 0090559:regulation of membrane permeability 1902396:protein localization to bicellular tight junction 0051493:regulation of cytoskeleton organization 0072659:protein localization to plasma membrane 0098609:cell-cell adhesion 0070830:bicellular tight junction assembly 0042803:protein homodimerization activity 0035633:maintenance of blood-brain barrier 0034260:negative regulation of GTPase activity 0005923:bicellular tight junction 0007179:transforming growth factor beta receptor signaling pathway 0030198:extracellular matrix organization 0045296:cadherin binding 0006954:inflammatory response 2000810:regulation of bicellular tight junction assembly 0031410:cytoplasmic vesicle 1901731:positive regulation of platelet aggregation 0070160:tight junction
PDB	1NBQ ; 4ODB ; 3TSZ ; 3EOY
Drugbank	NA
KEGG	hsa:50848

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Name: Alcohol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0416	Shan Shen	山参	NA	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera