HIT-result

Type	Detail
Target ID	T24LWC
Protein Name	Sodium-dependent dopamine transporter
Uniprot ID	Q01959
Protein Name Alias	DA transporter; DAT; Solute carrier family 6 member 3
Gene ID	6531
Gene Symbol	SLC6A3
Gene Alias	DAT1
TTD	T55959: Successful target
Pfam	PF00209
GO	0051721:protein phosphatase 2A binding 0015844:monoamine transport 0009986:cell surface 0030424:axon 0016021:integral component of membrane 0005334:norepinephrine:sodium symporter activity 0042493:response to drug 0007595:lactation 0007626:locomotory behavior 0035094:response to nicotine 0005330:dopamine:sodium symporter activity 0040018:positive regulation of multicellular organism growth 0021984:adenohypophysis development 0043025:neuronal cell body 0016600:flotillin complex 0032809:neuronal cell body membrane 0015872:dopamine transport 0042220:response to cocaine 0005102:signaling receptor binding 0046872:metal ion binding 0060134:prepulse inhibition 0015874:norepinephrine transport 0042136:neurotransmitter biosynthetic process 0008504:monoamine transmembrane transporter activity 0044877:protein-containing complex binding 0005886:plasma membrane 0042734:presynaptic membrane 0035240:dopamine binding 0051591:response to cAMP 0043005:neuron projection 0090494:dopamine uptake 0005887:integral component of plasma membrane 0042416:dopamine biosynthetic process 0005737:cytoplasm 0006836:neurotransmitter transport 0051583:dopamine uptake involved in synaptic transmission 0042053:regulation of dopamine metabolic process 0098691:dopaminergic synapse 0008144:drug binding 0002020:protease binding 0035725:sodium ion transmembrane transport 0045121:membrane raft 0005326:neurotransmitter transmembrane transporter activity 0099056:integral component of presynaptic membrane 0045471:response to ethanol 0007608:sensory perception of smell 0010039:response to iron ion 0042420:dopamine catabolic process 0099055:integral component of postsynaptic membrane 0007568:aging 1990384:hyaloid vascular plexus regression 0047485:protein N-terminus binding
PDB	NA
Drugbank	DB01472 ; DB03701 ; DB01175 ; DB06148 ; DB06413 ; DB00285 ; DB09194 ; DB01363 ; DB01577 ; DB01576 ; DB12305 ; DB00458 ; DB00543 ; DB01442 ; DB00830 ; DB01104 ; DB00408 ; DB00182 ; DB01146 ; DB06156 ; DB06701 ; DB00852 ; DB04947 ; DB00422 ; DB06333 ; DB00726 ; DB00988 ; DB08824 ; DB14754 ; DB00191 ; DB00865 ; DB00907 ; DB01463 ; DB01105 ; DB01454 ; DB00745 ; DB01149 ; DB00476 ; DB00579 ; DB04821 ; DB00721 ; DB01161 ; DB00454 ; DB00245 ; DB01114 ; DB01238 ; DB00937 ; DB01156 ; DB06700
KEGG	hsa:6531

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H1222	Huai Hua	槐花	flower bud of japanese pagodatree	Sophora japonica
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0132	Li Lu	藜芦	Black falsehellebore	Veratrum nigrum
H1227	Huai Zhi	槐枝	NA	Sophora japonica
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H1226	Huai Shan Yao	淮山药	rhizome of biglcaf yam	Rhizoma dioscoreae
H1007	Dou You	豆油	Soybean oil	Glycine max
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0995	Dong Chong Xia Cao	冬虫夏草	Aweto	Cordyceps sinensis
H0533	Teng Ku Shen	藤苦参	NA	Sophora flavescens
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0852	Zi Tan	紫檀	Burmacoast padauk	Pterocarpus indicus
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0026	Jiang	姜	Soybean paste	Glycine max
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H0560	Cao Bei Mu	草贝母	Indian iphigenia	Iphigenia indica
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H0979	Di Yu	地榆	Garden burnet	Sanguisorba officinalis
H0906	Ci Wan	刺苋	spiny amaranth	Amaranthus spinosus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0111	Ku Shen	苦参	Lightyellow sophora	Sophora flavescens
H0575	Tu Ku Shen	土苦参	all-grass of hooker winghead	Sophora flavescens
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H0792	Zhang Yu	章鱼	Common atlantic octopus	Octopus vulgaris
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0129	Le Xian Cai	勒苋菜	NA	Amaranthus spinosus
H1124	Guang Jin Qian Cao	广金钱草	Snowbellleaf tickclover	Desmodium styracifolium
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1225	Huai Mi	槐米	NA	Sophora japonica
H1224	Huai Jiao	槐角	pod of japanese pagodatree	Sophora japonica
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H0416	Shan Shen	山参	NA	Panax ginseng
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0980	Di Yu Tan	地榆炭	Garden burnet	Sanguisorba officinalis
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis

Target Description

Related Compounds (Total: 7)

Related Herbs (Total: 59)