Compound Description

ID:   C0398 Common name:   Sertraline
IUPAC:  (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine CAS:  NA
Chembl ID:   CHEMBL809 Pubchem ID:   CID:68617
Formula:  C17H17Cl2N TCM-ID:  TCMC2064
Smiles:  CN[C@H]1CC[C@H](c2c1cccc2)c1ccc(c(c1)Cl)Cl
Alias:

NA
Structure:

Related Targets  (Total: 11)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T25RHJ Sodium-dependent serotonin transporterSLC6A4 P31645
A 2 Reference(s)
T14B56 Translationally-controlled tumor proteinTPT1 P13693
A 1 Reference(s)
T70U24 Sigma non-opioid intracellular receptor 1SIGMAR1 Q99720
A 1 Reference(s)
T24LWC Sodium-dependent dopamine transporterSLC6A3 Q01959
A 1 Reference(s)
T11ZYR Cytochrome P450 2D6CYP2D6 P10635
A 1 Reference(s)
T83ENN Solute carrier family 22 member 3SLC22A3 O75751
B 1 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
B 1 Reference(s)
T76SUY Solute carrier family 22 member 2SLC22A2 O15244
B 1 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
C 1 Reference(s)
T97ZTQ 5-hydroxytryptamine receptor 1BHTR1B P28222
C 1 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens