HIT-result

Target Description

Type	Detail
Target ID	T83ENN
Protein Name	Solute carrier family 22 member 3
Uniprot ID	O75751
Protein Name Alias	Extraneuronal monoamine transporter; EMT; Organic cation transporter 3
Gene ID	6581
Gene Symbol	SLC22A3
Gene Alias	EMTH; OCT3
TTD	T55948: Research target
Pfam	PF07690
GO	0006836:neurotransmitter transport 0015695:organic cation transport 0098793:presynapse 0051615:histamine uptake 1901998:toxin transport 0072530:purine-containing compound transmembrane transport 0051620:norepinephrine uptake 0015651:quaternary ammonium group transmembrane transporter activity 0019534:toxin transmembrane transporter activity 0042908:xenobiotic transport 0015844:monoamine transport 0008514:organic anion transmembrane transporter activity 0090494:dopamine uptake 0005887:integral component of plasma membrane 0051610:serotonin uptake 0008504:monoamine transmembrane transporter activity 0015711:organic anion transport 0005886:plasma membrane 0005330:dopamine:sodium symporter activity 0150104:transport across blood-brain barrier 0016020:membrane 0001692:histamine metabolic process 0015697:quaternary ammonium group transport 0015101:organic cation transmembrane transporter activity 0005326:neurotransmitter transmembrane transporter activity 0015718:monocarboxylic acid transport 0043025:neuronal cell body 0032098:regulation of appetite 0051625:epinephrine uptake
PDB	NA
Drugbank	DB00182 ; DB00536 ; DB05381 ; DB08838 ; DB01577 ; DB13943 ; DB08841 ; DB00331 ; DB01042 ; DB13956 ; DB00396 ; DB13952 ; DB00184 ; DB08882 ; DB00526 ; DB00938 ; DB00541 ; DB14006 ; DB00718 ; DB00762 ; DB13954 ; DB00983 ; DB00783 ; DB00448 ; DB01151 ; DB13953 ; DB00122 ; DB00457 ; DB00458 ; DB00709 ; DB01035 ; DB00368 ; DB13944 ; DB00413 ; DB00501 ; DB08837 ; DB13955 ; DB00988 ; DB00575 ; DB00925
KEGG	hsa:6581

Type

Detail

Target ID

T83ENN

Protein Name

Solute carrier family 22 member 3

Uniprot ID

O75751

Protein Name Alias

Extraneuronal monoamine transporter; EMT; Organic cation transporter 3

Gene ID

6581

Gene Symbol

SLC22A3

Gene Alias

EMTH; OCT3

TTD

T55948: Research target

Pfam

PF07690

0006836:neurotransmitter transport

0015695:organic cation transport

0098793:presynapse

0051615:histamine uptake

1901998:toxin transport

0072530:purine-containing compound transmembrane transport

0051620:norepinephrine uptake

0015651:quaternary ammonium group transmembrane transporter activity

0019534:toxin transmembrane transporter activity

0042908:xenobiotic transport

0015844:monoamine transport

0008514:organic anion transmembrane transporter activity

0090494:dopamine uptake

0005887:integral component of plasma membrane

0051610:serotonin uptake

0008504:monoamine transmembrane transporter activity

0015711:organic anion transport

0005886:plasma membrane

0005330:dopamine:sodium symporter activity

0150104:transport across blood-brain barrier

0016020:membrane

0001692:histamine metabolic process

0015697:quaternary ammonium group transport

0015101:organic cation transmembrane transporter activity

0005326:neurotransmitter transmembrane transporter activity

0015718:monocarboxylic acid transport

0043025:neuronal cell body

0032098:regulation of appetite

0051625:epinephrine uptake

PDB

Drugbank

DB00182 ; DB00536 ; DB05381 ; DB08838 ; DB01577 ; DB13943 ; DB08841 ; DB00331 ; DB01042 ; DB13956 ; DB00396 ; DB13952 ; DB00184 ; DB08882 ; DB00526 ; DB00938 ; DB00541 ; DB14006 ; DB00718 ; DB00762 ; DB13954 ; DB00983 ; DB00783 ; DB00448 ; DB01151 ; DB13953 ; DB00122 ; DB00457 ; DB00458 ; DB00709 ; DB01035 ; DB00368 ; DB13944 ; DB00413 ; DB00501 ; DB08837 ; DB13955 ; DB00988 ; DB00575 ; DB00925

KEGG

hsa:6581

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1228	Huang Bai	黄柏	Amur corktree	Phellodendron amurense
H0029	Jiang Huang Lian	姜黄连	Coptis deltoidea	Coptis chinensis
H1230	Huang Bai Fen	黄柏粉	Amur corktree	Phellodendron amurense
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H0872	Chuan Huang Lian	川黄连	rhizome of chinese goldthread	Coptis chinensis
H0082	Jiu Huang Lian	酒黄连	Coptis deltoidea	Coptis chinensis
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H1243	Huang Lian Xu	黄连须	Coptis deltoidea	Coptis chinensis
H0682	Xiong Huang Lian	雄黄连	Coptis deltoidea	Coptis chinensis
H1231	Huang Bai Tan	黄柏炭	Amur corktree	Phellodendron amurense
H1242	Huang Lian Gan Jin Gao	黄连干浸膏	Coptis deltoidea	Coptis chinensis
H0827	Zhu Hong Jun	竹红菌	Bambusa hypocrella*	Hypocrella bambusae
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0966	Di Ding	地丁	All - grass of tokyo violet	Corydalis bungeana
H0706	Yan Hu Suo	延胡索	Yanhusuo	Corydalis yanhusuo
H0704	Yan Guan Huang Bai	盐关黄柏	Amur cork tree	Phellodendron amurense
H1241	Huang Lian	黄连	Coptis deltoidea	Coptis chinensis
H0785	Ze Xi Huang Lian	择细黄连	Coptis deltoidea	Coptis chinensis
H1115	Guan Huang Bai	关黄柏	Amur cork tree	Phellodendron amurense
H0651	Xiang Yuan	香橼	Wilson citron	Citrus medica
H0760	Yu Huang Lian	萸黄连	Coptis deltoidea	Coptis chinensis
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0105	Ku Di Ding	苦地丁	Bunge corydalis	Corydalis bungeana
H0633	Xia Tian Wu	夏天无	Decumbent corydalis	Corydalis decumbens
H1068	Bai He Liu Jin Gao	百合流浸膏	Lily	Lilium brownii
H1061	Bai He	百合	Lily	Lilium brownii
H0652	Xiang Yuan Pi	香橼皮	Wilson citron	Citrus medica
H0233	Mao Liang Mian Zhen	毛两面针	NA	Zanthoxylum nitidum

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 30)