Compound Description
| ID: C0388 | Common name: Sanguinarium |
| IUPAC: NA | CAS: CAS:2447-54-3 |
| Chembl ID: CHEMBL417799 | Pubchem ID: CID:5154 |
| Formula: C20H14NO4 | TCM-ID: TCMC2044 |
| Smiles: C[n+]1cc2c3OCOc3ccc2c2c1c1cc3OCOc3cc1cc2 | |
| Alias:
Sanguinarine;
13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium; Pseudochelerythrine; Sangrovit; Sanguinarin; Sanguinarium; UI5 |
Structure:
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Related Targets (Total: 8)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
A | 1 Reference(s) |
| T92FAW | Dual specificity protein phosphatase 1 | DUSP1 |
P28562 |
A | 2 Reference(s) |
| T02P7Q | Dihydrofolate reductase | DHFR |
P00374 |
A | 1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
A | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
A | 1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
| T83ENN | Solute carrier family 22 member 3 | SLC22A3 |
O75751 |
A | 1 Reference(s) |
| T33KFW | Matrilysin | MMP7 |
P09237 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0105 | Ku Di Ding | 苦地丁 | Bunge corydalis | Corydalis bungeana |
| H0233 | Mao Liang Mian Zhen | 毛两面针 | NA | Zanthoxylum nitidum |
| H0757 | Ying Su Ke | 罂粟壳 | Opium poppy pericarp | Papaver somniferum |
| H0248 | Mi Ying Su Ke | 蜜罂粟壳 | Opium poppy | Papaver somniferum |
| H0006 | Bai Qu Cai | 白屈菜 | Greater celandine | Chelidonium majus |
| H0756 | Ying Su | 罂粟 | Opium poppy | Papaver somniferum |
| H0966 | Di Ding | 地丁 | All - grass of tokyo violet | Corydalis bungeana |
Ckey description of the interaction between compound and target