Compound Description
| ID: C0034 | Common name: Dopamine |
| IUPAC: 4-(2-aminoethyl)benzene-1,2-diol | CAS: CAS:51-61-6 |
| Chembl ID: CHEMBL59 | Pubchem ID: CID:681 |
| Formula: C8H11NO2 | TCM-ID: TCMC1083 |
| Smiles: NCCc1ccc(c(c1)O)O | |
| Alias:
Pyrocatechol, 4-(2-aminoethyl)-;
4-(2-Aminoethyl)-1,2-benzenediol; 2-(3,4-Dihydroxyphenyl)-1-ethanamine; 2-(3,4-Dihydroxyphenyl)ethylamine; 3,4-Dihydroxyphenethylamine; 3,4-Dihydroxyphenylethylamine; 3-Hydroxytyramine; 4-(2-Aminoethyl)catechol; 4-(2-Aminoethyl)pyrocatechol; Dopamin; Dopamine; Dophamine; Duobaan; Hydroxytyramin; NSC 173182; Oxytyramine; α-(3,4-Dihydroxyphenyl)-β-aminoethane |
Structure:
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Related Targets (Total: 20)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T64BED | 5-hydroxytryptamine receptor 2A | HTR2A |
P28223 |
A | 1 Reference(s) |
| T48ZIG | D(2) dopamine receptor | DRD2 |
P14416 |
A | 4 Reference(s) |
| T77RFX | Alpha-2A adrenergic receptor | ADRA2A |
P08913 |
A | 1 Reference(s) |
| T09HVO | Sodium/hydrogen exchanger 3 | SLC9A3 |
P48764 |
A | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
A | 1 Reference(s) |
| T58K2N | Calmodulin-3;Calmodulin-1;Calmodulin-2 | CALM3;CALM1;CALM2 |
P0DP25;P0DP23;P0DP24 |
B | 1 Reference(s) |
| T24LWC | Sodium-dependent dopamine transporter | SLC6A3 |
Q01959 |
B | 1 Reference(s) |
| T42O1D | Delta-type opioid receptor | OPRD1 |
P41143 |
B | 1 Reference(s) |
| T23TJV | Tyrosine 3-monooxygenase | TH |
P07101 |
B | 2 Reference(s) |
| T81LOK | Nuclear receptor subfamily 4 group A member 2 | NR4A2 |
P43354 |
B | 1 Reference(s) |
| T49IR9 | D(4) dopamine receptor | DRD4 |
P21917 |
B | 1 Reference(s) |
| T27BN7 | Protachykinin-1 | TAC1 |
P20366 |
B | 1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
C | 1 Reference(s) |
| T74WWP | Peroxisome proliferator-activated receptor delta | PPARD |
Q03181 |
C | 2 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
C | 1 Reference(s) |
| T58CAO | Alpha-synuclein | SNCA |
P37840 |
C | 1 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
C | 1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 4)
Ckey description of the interaction between compound and target