HIT-result

Target Description

Type	Detail
Target ID	T27BN7
Protein Name	Protachykinin-1
Uniprot ID	P20366
Protein Name Alias	PPT
Gene ID	6863
Gene Symbol	TAC1
Gene Alias	NKA; NKNA; TAC2
TTD	NA
Pfam	PF02202
GO	0045202:synapse 0046878:positive regulation of saliva secretion 0010459:negative regulation of heart rate 0009725:response to hormone 0019732:antifungal humoral response 2000854:positive regulation of corticosterone secretion 0007616:long-term memory 0008217:regulation of blood pressure 0051496:positive regulation of stress fiber assembly 1901215:negative regulation of neuron death 0006954:inflammatory response 0008306:associative learning 0032496:response to lipopolysaccharide 0007204:positive regulation of cytosolic calcium ion concentration 0009582:detection of abiotic stimulus 0048265:response to pain 0001878:response to yeast 0005615:extracellular space 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0050829:defense response to Gram-negative bacterium 0007320:insemination 1902093:positive regulation of flagellated sperm motility 0031836:neuromedin K receptor binding 0045778:positive regulation of ossification 0048018:receptor ligand activity 0031640:killing of cells of other organism 0019233:sensory perception of pain 0031835:substance P receptor binding 0010634:positive regulation of epithelial cell migration 0050671:positive regulation of lymphocyte proliferation 0035815:positive regulation of renal sodium excretion 0045760:positive regulation of action potential 1904058:positive regulation of sensory perception of pain 0043278:response to morphine 0003085:negative regulation of systemic arterial blood pressure 0032224:positive regulation of synaptic transmission, cholinergic 1990090:cellular response to nerve growth factor stimulus 0005576:extracellular region 0045087:innate immune response 0043025:neuronal cell body 0007217:tachykinin receptor signaling pathway 0005886:plasma membrane 0050965:detection of temperature stimulus involved in sensory perception of pain 0050830:defense response to Gram-positive bacterium 0007186:G protein-coupled receptor signaling pathway 0051930:regulation of sensory perception of pain 0002675:positive regulation of acute inflammatory response 0030424:axon 0031837:substance K receptor binding 0007218:neuropeptide signaling pathway 0007267:cell-cell signaling 1901216:positive regulation of neuron death 0032230:positive regulation of synaptic transmission, GABAergic 0007268:chemical synaptic transmission 0019731:antibacterial humoral response
PDB	4HOM ; 2KSB ; 2KSA ; 2B19 ; 2KS9
Drugbank	NA
KEGG	hsa:6863

Type

Detail

Target ID

T27BN7

Protein Name

Protachykinin-1

Uniprot ID

P20366

Protein Name Alias

PPT

Gene ID

6863

Gene Symbol

TAC1

Gene Alias

NKA; NKNA; TAC2

TTD

Pfam

PF02202

0045202:synapse

0046878:positive regulation of saliva secretion

0010459:negative regulation of heart rate

0009725:response to hormone

0019732:antifungal humoral response

2000854:positive regulation of corticosterone secretion

0007616:long-term memory

0008217:regulation of blood pressure

0051496:positive regulation of stress fiber assembly

1901215:negative regulation of neuron death

0006954:inflammatory response

0008306:associative learning

0032496:response to lipopolysaccharide

0007204:positive regulation of cytosolic calcium ion concentration

0009582:detection of abiotic stimulus

0048265:response to pain

0001878:response to yeast

0005615:extracellular space

0061844:antimicrobial humoral immune response mediated by antimicrobial peptide

0050829:defense response to Gram-negative bacterium

0007320:insemination

1902093:positive regulation of flagellated sperm motility

0031836:neuromedin K receptor binding

0045778:positive regulation of ossification

0048018:receptor ligand activity

0031640:killing of cells of other organism

0019233:sensory perception of pain

0031835:substance P receptor binding

0010634:positive regulation of epithelial cell migration

0050671:positive regulation of lymphocyte proliferation

0035815:positive regulation of renal sodium excretion

0045760:positive regulation of action potential

1904058:positive regulation of sensory perception of pain

0043278:response to morphine

0003085:negative regulation of systemic arterial blood pressure

0032224:positive regulation of synaptic transmission, cholinergic

1990090:cellular response to nerve growth factor stimulus

0005576:extracellular region

0045087:innate immune response

0043025:neuronal cell body

0007217:tachykinin receptor signaling pathway

0005886:plasma membrane

0050965:detection of temperature stimulus involved in sensory perception of pain

0050830:defense response to Gram-positive bacterium

0007186:G protein-coupled receptor signaling pathway

0051930:regulation of sensory perception of pain

0002675:positive regulation of acute inflammatory response

0030424:axon

0031837:substance K receptor binding

0007218:neuropeptide signaling pathway

0007267:cell-cell signaling

1901216:positive regulation of neuron death

0032230:positive regulation of synaptic transmission, GABAergic

0007268:chemical synaptic transmission

0019731:antibacterial humoral response

PDB

4HOM ; 2KSB ; 2KSA ; 2B19 ; 2KS9

Drugbank

KEGG

hsa:6863

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0418	Shan Yin Chen	山茵陈	Capillary wormwood	Artemisia capillaris
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1226	Huai Shan Yao	淮山药	rhizome of biglcaf yam	Rhizoma dioscoreae
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0164	Ban Zhi Lian	半枝莲	Barbed skullcap	Scutellaria barbata
H0854	Zi Wei Gen Pi	紫葳根皮	NA	Campsis grandiflora
H0892	Chuan Xiong	川芎	cnidium officinale	Cnidium officinale
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H0239	Bei Sha Shen	北沙参	Coastal glehnia	Glehnia littoralis
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0745	Yin Chen Hao	茵陈蒿	Capillary wormwood	Artemisia capillaris
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0585	Tu Yin Chen Hao	土茵陈蒿	Capillary wormwood	Artemisia capillaris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0242	Bei Sha Shen Liu Jin Gao	北沙参流浸膏	Glehnia littoralis	Glehnia littoralis
H0119	La Jiao	辣椒	Bush redpepper	Capsicum frutescens
H0232	Mao He Zi	毛诃子	friot of belleric terminalia	Fructus terminaliae billericae
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0121	La Jiao Jin Chu Ye	辣椒浸出液	Bush redpepper	Capsicum frutescens
H0122	La Jiao Jin Gao	辣椒浸膏	Bush redpepper	Capsicum frutescens
H0893	Chuan Xiong Jin Gao	川芎浸膏	cnidium officinale	Cnidium officinale
H0123	La Jiao Liu Jin Gao	辣椒流浸膏	Bush redpepper	Capsicum frutescens
H0746	Yin Chen Hao Gan Jin Gao	茵陈蒿干浸膏	Capillary wormwood	Artemisia capillaris

Target Description

Related Compounds (Total: 5)

Related Herbs (Total: 24)