HIT-result

Target Description

Type	Detail
Target ID	T55EIL
Protein Name	Homeobox protein OTX2
Uniprot ID	P32243
Protein Name Alias	Orthodenticle homolog 2
Gene ID	5015
Gene Symbol	OTX2
Gene Alias	NA
TTD	NA
Pfam	PF03529 ; PF00046
GO	0005634:nucleus 0030901:midbrain development 0040036:regulation of fibroblast growth factor receptor signaling pathway 0071542:dopaminergic neuron differentiation 0065003:protein-containing complex assembly 0008589:regulation of smoothened signaling pathway 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0000785:chromatin 0030900:forebrain development 0032991:protein-containing complex 0090009:primitive streak formation 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 0008190:eukaryotic initiation factor 4E binding 0006357:regulation of transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 1990837:sequence-specific double-stranded DNA binding 0045944:positive regulation of transcription by RNA polymerase II 0007411:axon guidance 0040019:positive regulation of embryonic development 0030426:growth cone 2000543:positive regulation of gastrulation
PDB	NA
Drugbank	NA
KEGG	hsa:5015

Type

Detail

Target ID

T55EIL

Protein Name

Homeobox protein OTX2

Uniprot ID

P32243

Protein Name Alias

Orthodenticle homolog 2

Gene ID

5015

Gene Symbol

OTX2

Gene Alias

TTD

Pfam

PF03529 ; PF00046

0005634:nucleus

0030901:midbrain development

0040036:regulation of fibroblast growth factor receptor signaling pathway

0071542:dopaminergic neuron differentiation

0065003:protein-containing complex assembly

0008589:regulation of smoothened signaling pathway

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0000785:chromatin

0030900:forebrain development

0032991:protein-containing complex

0090009:primitive streak formation

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045893:positive regulation of transcription, DNA-templated

0008190:eukaryotic initiation factor 4E binding

0006357:regulation of transcription by RNA polymerase II

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

1990837:sequence-specific double-stranded DNA binding

0045944:positive regulation of transcription by RNA polymerase II

0007411:axon guidance

0040019:positive regulation of embryonic development

0030426:growth cone

2000543:positive regulation of gastrulation

PDB

Drugbank

KEGG

hsa:5015

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0416	Shan Shen	山参	NA	Panax ginseng
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 12)