Target Description

Type Detail
Target ID T22ZML
Protein Name Achaete-scute homolog 1
Uniprot ID P50553
Protein Name Alias ASH-1;  hASH1;  Class A basic helix-loop-helix protein 46;  bHLHa46
Gene ID 429
Gene Symbol ASCL1
Gene Alias ASH1;  BHLHA46;  HASH1
TTD NA
Pfam PF00010
GO
0042802:identical protein binding

0005634:nucleus

0048666:neuron development

0045747:positive regulation of Notch signaling pathway

0030182:neuron differentiation

0050883:musculoskeletal movement, spinal reflex action

0060163:subpallium neuron fate commitment

0060165:regulation of timing of subpallium neuron differentiation

0048469:cell maturation

0003682:chromatin binding

0001764:neuron migration

0010468:regulation of gene expression

0021902:commitment of neuronal cell to specific neuron type in forebrain

0090575:RNA polymerase II transcription regulator complex

0061100:lung neuroendocrine cell differentiation

0043525:positive regulation of neuron apoptotic process

0021527:spinal cord association neuron differentiation

0030856:regulation of epithelial cell differentiation

0021530:spinal cord oligodendrocyte cell fate specification

0061549:sympathetic ganglion development

0021987:cerebral cortex development

0045892:negative regulation of transcription, DNA-templated

0032526:response to retinoic acid

0007423:sensory organ development

0061103:carotid body glomus cell differentiation

0045787:positive regulation of cell cycle

0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding

0071259:cellular response to magnetism

0021892:cerebral cortex GABAergic interneuron differentiation

0061102:stomach neuroendocrine cell differentiation

0010226:response to lithium ion

0007507:heart development

0003358:noradrenergic neuron development

0060166:olfactory pit development

0021750:vestibular nucleus development

0007346:regulation of mitotic cell cycle

0051593:response to folic acid

0000785:chromatin

0070888:E-box binding

0060579:ventral spinal cord interneuron fate commitment

0043066:negative regulation of apoptotic process

0045665:negative regulation of neuron differentiation

0048665:neuron fate specification

0046983:protein dimerization activity

0021954:central nervous system neuron development

0050769:positive regulation of neurogenesis

0045666:positive regulation of neuron differentiation

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0043425:bHLH transcription factor binding

0007400:neuroblast fate determination

0048663:neuron fate commitment

0000122:negative regulation of transcription by RNA polymerase II

0003359:noradrenergic neuron fate commitment

0007219:Notch signaling pathway

0003700:DNA-binding transcription factor activity

0007405:neuroblast proliferation

0006357:regulation of transcription by RNA polymerase II

0014003:oligodendrocyte development

0022008:neurogenesis

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

0043025:neuronal cell body

1990837:sequence-specific double-stranded DNA binding

0061104:adrenal chromaffin cell differentiation

0050767:regulation of neurogenesis

0045944:positive regulation of transcription by RNA polymerase II

0070849:response to epidermal growth factor

0048485:sympathetic nervous system development

0060487:lung epithelial cell differentiation

2000179:positive regulation of neural precursor cell proliferation

PDB NA
Drugbank NA
KEGG hsa:429

Related Compounds  (Total: 1)

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C0867
Name: Alcohol


Related Herbs  (Total: 12)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0416 Shan Shen山参 NAPanax ginseng
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0938 Da Suan大蒜 GarlicAllium sativum
H0357 Ren Shen人参 GinsengPanax ginseng
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens