HIT-result

Target Description

Type	Detail
Target ID	T64E3A
Protein Name	Aminopeptidase N
Uniprot ID	P15144
Protein Name Alias	AP-N; hAPN; EC 3.4.11.2; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD antigen CD13
Gene ID	290
Gene Symbol	ANPEP
Gene Alias	APN; CD13; PEPN
TTD	T67272: Clinical Trial target
Pfam	PF11838 ; PF01433
GO	0030667:secretory granule membrane 0038023:signaling receptor activity 0070062:extracellular exosome 0006508:proteolysis 0070006:metalloaminopeptidase activity 0008237:metallopeptidase activity 0043171:peptide catabolic process 0004177:aminopeptidase activity 0005765:lysosomal membrane 0005615:extracellular space 0030154:cell differentiation 0042277:peptide binding 0005886:plasma membrane 0016021:integral component of membrane 0043312:neutrophil degranulation 0005793:endoplasmic reticulum-Golgi intermediate compartment 0008270:zinc ion binding 0005737:cytoplasm 0007165:signal transduction 0001525:angiogenesis 0008217:regulation of blood pressure 0001618:virus receptor activity
PDB	4FYT ; 4FYQ ; 6ATK ; 4FYS ; 6U7F ; 7AEW ; 5LHD ; 4FYR ; 6U7E ; 6U7G
Drugbank	DB06773 ; DB00973 ; DB06196
KEGG	hsa:290

Type

Detail

Target ID

T64E3A

Protein Name

Aminopeptidase N

Uniprot ID

P15144

Protein Name Alias

AP-N; hAPN; EC 3.4.11.2; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD antigen CD13

Gene ID

290

Gene Symbol

ANPEP

Gene Alias

APN; CD13; PEPN

TTD

T67272: Clinical Trial target

Pfam

PF11838 ; PF01433

0030667:secretory granule membrane

0038023:signaling receptor activity

0070062:extracellular exosome

0006508:proteolysis

0070006:metalloaminopeptidase activity

0008237:metallopeptidase activity

0043171:peptide catabolic process

0004177:aminopeptidase activity

0005765:lysosomal membrane

0005615:extracellular space

0030154:cell differentiation

0042277:peptide binding

0005886:plasma membrane

0016021:integral component of membrane

0043312:neutrophil degranulation

0005793:endoplasmic reticulum-Golgi intermediate compartment

0008270:zinc ion binding

0005737:cytoplasm

0007165:signal transduction

0001525:angiogenesis

0008217:regulation of blood pressure

0001618:virus receptor activity

PDB

4FYT ; 4FYQ ; 6ATK ; 4FYS ; 6U7F ; 7AEW ; 5LHD ; 4FYR ; 6U7E ; 6U7G

Drugbank

DB06773 ; DB00973 ; DB06196

KEGG

hsa:290

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0416	Shan Shen	山参	NA	Panax ginseng
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 12)