HIT-result

Type	Detail
Target ID	T74SS7
Protein Name	Glutamate receptor ionotropic, NMDA 2A
Uniprot ID	Q12879
Protein Name Alias	GluN2A
Gene ID	2903
Gene Symbol	GRIN2A
Gene Alias	NMDAR2A
TTD	T22285: Successful target
Pfam	PF01094 ; PF00060 ; PF10565 ; PF10613
GO	0060079:excitatory postsynaptic potential 0042428:serotonin metabolic process 0042417:dopamine metabolic process 0005789:endoplasmic reticulum membrane 0042493:response to drug 0030431:sleep 0007268:chemical synaptic transmission 0038023:signaling receptor activity 0022008:neurogenesis 0043197:dendritic spine 0099061:integral component of postsynaptic density membrane 0097202:activation of cysteine-type endopeptidase activity 1903539:protein localization to postsynaptic membrane 0017146:NMDA selective glutamate receptor complex 2000310:regulation of NMDA receptor activity 0009986:cell surface 0007420:brain development 0001964:startle response 0097553:calcium ion transmembrane import into cytosol 0007215:glutamate receptor signaling pathway 0060291:long-term synaptic potentiation 0009611:response to wounding 0043065:positive regulation of apoptotic process 0022849:glutamate-gated calcium ion channel activity 0015276:ligand-gated ion channel activity 0097060:synaptic membrane 0005886:plasma membrane 0042734:presynaptic membrane 0033058:directional locomotion 0098978:glutamatergic synapse 0030659:cytoplasmic vesicle membrane 0005887:integral component of plasma membrane 0007611:learning or memory 0008270:zinc ion binding 0048167:regulation of synaptic plasticity 0001975:response to amphetamine 0007613:memory 0098839:postsynaptic density membrane 0019233:sensory perception of pain 0004972:NMDA glutamate receptor activity 0098976:excitatory chemical synaptic transmission 0014069:postsynaptic density 0008542:visual learning 0008021:synaptic vesicle 0045471:response to ethanol 0001540:amyloid-beta binding 0042177:negative regulation of protein catabolic process
PDB	5H8H ; 6IRA ; 5H8F ; 6IRG ; 6IRF ; 5TP9 ; 5I2N ; 5KCJ ; 3NFL ; 5I2K ; 5KDT ; 6IRH ; 5TPA ; 5H8Q ; 5H8N
Drugbank	DB00418 ; DB06151 ; DB01174 ; DB06738 ; DB06741 ; DB00193 ; DB00659 ; DB04896 ; DB00333 ; DB01708 ; DB00843 ; DB00289 ; DB01043 ; DB09409 ; DB00312 ; DB01520 ; DB11823 ; DB13146 ; DB00949 ; DB00142 ; DB09481 ; DB00874 ; DB01159 ; DB00454 ; DB01238 ; DB00228 ; DB00145
KEGG	hsa:2903

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Name: Morphine

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Name: Alcohol

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Name: Chelerythrine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0416	Shan Shen	山参	NA	Panax ginseng
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H1163	He Bao Cao	荷包草	NA	Lamprocapnos spectabilis
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0233	Mao Liang Mian Zhen	毛两面针	NA	Zanthoxylum nitidum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0357	Ren Shen	人参	Ginseng	Panax ginseng