Target Description

Type Detail
Target ID T74SS7
Protein Name Glutamate receptor ionotropic, NMDA 2A
Uniprot ID Q12879
Protein Name Alias GluN2A
Gene ID 2903
Gene Symbol GRIN2A
Gene Alias NMDAR2A
TTD T22285: Successful target
Pfam PF01094 ; PF00060 ; PF10565 ; PF10613
GO
0060079:excitatory postsynaptic potential

0042428:serotonin metabolic process

0042417:dopamine metabolic process

0005789:endoplasmic reticulum membrane

0042493:response to drug

0030431:sleep

0007268:chemical synaptic transmission

0038023:signaling receptor activity

0022008:neurogenesis

0043197:dendritic spine

0099061:integral component of postsynaptic density membrane

0097202:activation of cysteine-type endopeptidase activity

1903539:protein localization to postsynaptic membrane

0017146:NMDA selective glutamate receptor complex

2000310:regulation of NMDA receptor activity

0009986:cell surface

0007420:brain development

0001964:startle response

0097553:calcium ion transmembrane import into cytosol

0007215:glutamate receptor signaling pathway

0060291:long-term synaptic potentiation

0009611:response to wounding

0043065:positive regulation of apoptotic process

0022849:glutamate-gated calcium ion channel activity

0015276:ligand-gated ion channel activity

0097060:synaptic membrane

0005886:plasma membrane

0042734:presynaptic membrane

0033058:directional locomotion

0098978:glutamatergic synapse

0030659:cytoplasmic vesicle membrane

0005887:integral component of plasma membrane

0007611:learning or memory

0008270:zinc ion binding

0048167:regulation of synaptic plasticity

0001975:response to amphetamine

0007613:memory

0098839:postsynaptic density membrane

0019233:sensory perception of pain

0004972:NMDA glutamate receptor activity

0098976:excitatory chemical synaptic transmission

0014069:postsynaptic density

0008542:visual learning

0008021:synaptic vesicle

0045471:response to ethanol

0001540:amyloid-beta binding

0042177:negative regulation of protein catabolic process

PDB 5H8H ; 6IRA ; 5H8F ; 6IRG ; 6IRF ; 5TP9 ; 5I2N ; 5KCJ ; 3NFL ; 5I2K ; 5KDT ; 6IRH ; 5TPA ; 5H8Q ; 5H8N
Drugbank DB00418 ; DB06151 ; DB01174 ; DB06738 ; DB06741 ; DB00193 ; DB00659 ; DB04896 ; DB00333 ; DB01708 ; DB00843 ; DB00289 ; DB01043 ; DB09409 ; DB00312 ; DB01520 ; DB11823 ; DB13146 ; DB00949 ; DB00142 ; DB09481 ; DB00874 ; DB01159 ; DB00454 ; DB01238 ; DB00228 ; DB00145
KEGG hsa:2903

Related Compounds  (Total: 3)

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C0226
Name: Morphine
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C0867
Name: Alcohol
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C1227
Name: Chelerythrine


Related Herbs  (Total: 19)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1163 He Bao Cao荷包草 NALamprocapnos spectabilis
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0357 Ren Shen人参 GinsengPanax ginseng
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0757 Ying Su Ke罂粟壳 Opium poppy pericarpPapaver somniferum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0248 Mi Ying Su Ke蜜罂粟壳 Opium poppyPapaver somniferum
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H0938 Da Suan大蒜 GarlicAllium sativum
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0233 Mao Liang Mian Zhen毛两面针 NAZanthoxylum nitidum
H0416 Shan Shen山参 NAPanax ginseng
H0756 Ying Su罂粟 Opium poppyPapaver somniferum