HIT-result

Target Description

Type	Detail
Target ID	T17LB4
Protein Name	High affinity immunoglobulin gamma Fc receptor I
Uniprot ID	P12314
Protein Name Alias	IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64
Gene ID	2209
Gene Symbol	FCGR1A
Gene Alias	FCG1; FCGR1; IGFR1
TTD	T10844: Research target
Pfam	PF00047 ; PF13895
GO	0061098:positive regulation of protein tyrosine kinase activity 0060333:interferon-gamma-mediated signaling pathway 0004888:transmembrane signaling receptor activity 0007165:signal transduction 0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 0006955:immune response 0006898:receptor-mediated endocytosis 0030669:clathrin-coated endocytic vesicle membrane 0050776:regulation of immune response 0007166:cell surface receptor signaling pathway 0006911:phagocytosis, engulfment 0019864:IgG binding 0005887:integral component of plasma membrane 0031901:early endosome membrane 0038096:Fc-gamma receptor signaling pathway involved in phagocytosis 0002862:negative regulation of inflammatory response to antigenic stimulus 0005886:plasma membrane
PDB	4X4M ; 3RJD ; 4W4O ; 4ZNE
Drugbank	DB00056 ; DB00289 ; DB00112 ; DB00707 ; DB00002 ; DB00087 ; DB00005 ; DB14962 ; DB00111 ; DB00028 ; DB06607 ; DB00110 ; DB00108 ; DB11767
KEGG	hsa:2209

Type

Detail

Target ID

T17LB4

Protein Name

High affinity immunoglobulin gamma Fc receptor I

Uniprot ID

P12314

Protein Name Alias

IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64

Gene ID

2209

Gene Symbol

FCGR1A

Gene Alias

FCG1; FCGR1; IGFR1

TTD

T10844: Research target

Pfam

PF00047 ; PF13895

0061098:positive regulation of protein tyrosine kinase activity

0060333:interferon-gamma-mediated signaling pathway

0004888:transmembrane signaling receptor activity

0007165:signal transduction

0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0006955:immune response

0006898:receptor-mediated endocytosis

0030669:clathrin-coated endocytic vesicle membrane

0050776:regulation of immune response

0007166:cell surface receptor signaling pathway

0006911:phagocytosis, engulfment

0019864:IgG binding

0005887:integral component of plasma membrane

0031901:early endosome membrane

0038096:Fc-gamma receptor signaling pathway involved in phagocytosis

0002862:negative regulation of inflammatory response to antigenic stimulus

0005886:plasma membrane

PDB

4X4M ; 3RJD ; 4W4O ; 4ZNE

Drugbank

DB00056 ; DB00289 ; DB00112 ; DB00707 ; DB00002 ; DB00087 ; DB00005 ; DB14962 ; DB00111 ; DB00028 ; DB06607 ; DB00110 ; DB00108 ; DB11767

KEGG

hsa:2209

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0416	Shan Shen	山参	NA	Panax ginseng
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 12)