Target Description

Type Detail
Target ID T08W1L
Protein Name Tumor necrosis factor receptor superfamily member 16
Uniprot ID P08138
Protein Name Alias Gp80-LNGFR;  Low affinity neurotrophin receptor p75NTR;  Low-affinity nerve growth factor receptor;  NGF receptor;  p75 ICD;  CD antigen CD271
Gene ID 4804
Gene Symbol NGFR
Gene Alias TNFRSF16
TTD T50942: Successful target
Pfam PF18422 ; PF00020 ; PF00531
GO
1902895:positive regulation of pri-miRNA transcription by RNA polymerase II

0040037:negative regulation of fibroblast growth factor receptor signaling pathway

0038023:signaling receptor activity

0048406:nerve growth factor binding

0001540:amyloid-beta binding

0015026:coreceptor activity

0005829:cytosol

0031625:ubiquitin protein ligase binding

0051799:negative regulation of hair follicle development

0004888:transmembrane signaling receptor activity

0014069:postsynaptic density

0048146:positive regulation of fibroblast proliferation

0048011:neurotrophin TRK receptor signaling pathway

0005887:integral component of plasma membrane

0035907:dorsal aorta development

0005886:plasma membrane

0032922:circadian regulation of gene expression

0016048:detection of temperature stimulus

0021675:nerve development

1900182:positive regulation of protein localization to nucleus

0016021:integral component of membrane

0043204:perikaryon

0043121:neurotrophin binding

0043066:negative regulation of apoptotic process

2001235:positive regulation of apoptotic signaling pathway

0005035:death receptor activity

0042488:positive regulation of odontogenesis of dentin-containing tooth

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0007417:central nervous system development

0005516:calmodulin binding

0009986:cell surface

0031267:small GTPase binding

0043065:positive regulation of apoptotic process

0051402:neuron apoptotic process

0005576:extracellular region

0005911:cell-cell junction

1904646:cellular response to amyloid-beta

0043197:dendritic spine

0050771:negative regulation of axonogenesis

1903588:negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

0001678:cellular glucose homeostasis

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

0031069:hair follicle morphogenesis

0042593:glucose homeostasis

0031293:membrane protein intracellular domain proteolysis

0050772:positive regulation of axonogenesis

0005654:nucleoplasm

0043281:regulation of cysteine-type endopeptidase activity involved in apoptotic process

0006886:intracellular protein transport

0007411:axon guidance

0005768:endosome

0030426:growth cone

0007266:Rho protein signal transduction

PDB 2N97 ; 5ZGG ; 2N83 ; 3EWV ; 2N80
Drugbank NA
KEGG hsa:4804

Related Compounds  (Total: 3)

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C0238
Name: Nandrolone
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C0503
Name: Astaxanthin
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C0867
Name: Alcohol


Related Herbs  (Total: 12)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0416 Shan Shen山参 NAPanax ginseng
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0357 Ren Shen人参 GinsengPanax ginseng
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0938 Da Suan大蒜 GarlicAllium sativum
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens