Target Description

Type Detail
Target ID T43WIP
Protein Name Cystine/glutamate transporter
Uniprot ID Q9UPY5
Protein Name Alias Amino acid transport system xc-;  Calcium channel blocker resistance protein CCBR1;  Solute carrier family 7 member 11;  xCT
Gene ID 23657
Gene Symbol SLC7A11
Gene Alias NA
TTD T11615: Clinical Trial target
Pfam PF13520
GO
0021756:striatum development

0009636:response to toxic substance

1901494:regulation of cysteine metabolic process

0005791:rough endoplasmic reticulum

0009986:cell surface

0016021:integral component of membrane

0035094:response to nicotine

0140206:dipeptide import across plasma membrane

2000211:regulation of glutamate metabolic process

0005856:cytoskeleton

0070527:platelet aggregation

0050900:leukocyte migration

0021591:ventricular system development

0050804:modulation of chemical synaptic transmission

0015179:L-amino acid transmembrane transporter activity

0051223:regulation of protein transport

0006749:glutathione metabolic process

0050807:regulation of synapse organization

0033029:regulation of neutrophil apoptotic process

0051775:response to redox state

0090461:glutamate homeostasis

0045177:apical part of cell

0005886:plasma membrane

0034775:glutathione transmembrane transport

0098712:L-glutamate import across plasma membrane

0014070:response to organic cyclic compound

0030534:adult behavior

0070306:lens fiber cell differentiation

1904717:regulation of AMPA glutamate receptor clustering

0034599:cellular response to oxidative stress

0048021:regulation of melanin biosynthetic process

1903204:negative regulation of oxidative stress-induced neuron death

0031526:brush border membrane

1903786:regulation of glutathione biosynthetic process

0006865:amino acid transport

0015327:cystine:glutamate antiporter activity

0060173:limb development

0042127:regulation of cell population proliferation

0048286:lung alveolus development

0008542:visual learning

0097449:astrocyte projection

PDB NA
Drugbank DB00142 ; DB08834 ; DB01098 ; DB00740 ; DB05540 ; DB06151 ; DB04348 ; DB08833 ; DB00795 ; DB00138 ; DB11590
KEGG hsa:23657

Related Compounds  (Total: 2)

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C0867
Name: Alcohol
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C1104
Name: adrenaline


Related Herbs  (Total: 12)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0938 Da Suan大蒜 GarlicAllium sativum
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0416 Shan Shen山参 NAPanax ginseng
H0357 Ren Shen人参 GinsengPanax ginseng
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis