HIT-result

Target Description

Type	Detail
Target ID	T71PEL
Protein Name	Excitatory amino acid transporter 2
Uniprot ID	P43004
Protein Name Alias	Glutamate/aspartate transporter II; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2
Gene ID	6506
Gene Symbol	SLC1A2
Gene Alias	EAAT2; GLT1
TTD	T95438: Research target
Pfam	PF00375
GO	0044297:cell body 0005313:L-glutamate transmembrane transporter activity 0070779:D-aspartate import across plasma membrane 0009986:cell surface 0070633:transepithelial transport 0015501:glutamate:sodium symporter activity 0150104:transport across blood-brain barrier 0005314:high-affinity glutamate transmembrane transporter activity 0007268:chemical synaptic transmission 0016020:membrane 0046872:metal ion binding 0098796:membrane protein complex 0006811:ion transport 0015813:L-glutamate transmembrane transport 0005886:plasma membrane 0098712:L-glutamate import across plasma membrane 0005887:integral component of plasma membrane 0006836:neurotransmitter transport 0097449:astrocyte projection 0045121:membrane raft 0099056:integral component of presynaptic membrane 0070207:protein homotrimerization 0070778:L-aspartate transmembrane transport
PDB	NA
Drugbank	DB00142 ; DB08868
KEGG	hsa:6506

Type

Detail

Target ID

T71PEL

Protein Name

Excitatory amino acid transporter 2

Uniprot ID

P43004

Protein Name Alias

Glutamate/aspartate transporter II; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2

Gene ID

6506

Gene Symbol

SLC1A2

Gene Alias

EAAT2; GLT1

TTD

T95438: Research target

Pfam

PF00375

0044297:cell body

0005313:L-glutamate transmembrane transporter activity

0070779:D-aspartate import across plasma membrane

0009986:cell surface

0070633:transepithelial transport

0015501:glutamate:sodium symporter activity

0150104:transport across blood-brain barrier

0005314:high-affinity glutamate transmembrane transporter activity

0007268:chemical synaptic transmission

0016020:membrane

0046872:metal ion binding

0098796:membrane protein complex

0006811:ion transport

0015813:L-glutamate transmembrane transport

0005886:plasma membrane

0098712:L-glutamate import across plasma membrane

0005887:integral component of plasma membrane

0006836:neurotransmitter transport

0097449:astrocyte projection

0045121:membrane raft

0099056:integral component of presynaptic membrane

0070207:protein homotrimerization

0070778:L-aspartate transmembrane transport

PDB

Drugbank

DB00142 ; DB08868

KEGG

hsa:6506

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Name: Dopa

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Name: Acetylcysteine

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Name: Alcohol

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Name: Cpg

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0416	Shan Shen	山参	NA	Panax ginseng
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 13)