Compound Description

ID:   C0855 Common name:   Acetylcysteine
IUPAC:  (2R)-2-acetamido-3-sulfanylpropanoic acid CAS:  CAS:616-91-1
Chembl ID:   CHEMBL600 Pubchem ID:   CID:12035
Formula:  C5H9NO3S TCM-ID:  TCMC620
Smiles:  SC[C@@H](C(=O)O)N=C(O)C
Alias:

Cysteine, N-acetyl-, L-;

N-Acetyl-L-cysteine;

(2R)-2-Acetamido-3-sulfanylpropanoic acid;

(2R)-2Acetamido-3-sulfanylpropanoic acid;

(R)-N-Acetylcysteine;

ACC;

Ac-Cys-OH;

Acetadote;

Acetilcysteina;

Acetylcysteine;

Airbron;

Asist;

Broncholysin;

Broncholysin (mucolytic);

Brunac;

Cysteplus;

Exomuc;

Fabrol;

Fluatox;

Fluibiotic;

Fluimicil;

Fluimicil Infantil;

Fluimucetin;

Fluimucil;

Fluimucil Antidot;

Flumil;

Fluprowit;

Hypotears;

L-Acetylcysteine;

L-N-Acetylcysteine;

Lysomucil;

Mentopin;

Mercapturic acid;

Mercapturic acid, (R)-;

Mucinac;

Muco Sanigen;

Mucocedyl;

Mucofilin;

Mucolator;

Mucolyticum;

Mucolyticum-Lappe;

Mucolytikum Lappe;

Mucomelt;

Mucomyst;

Mucosolvin;

Mucosten;

Mucret;

N-Acetyl-(R)-cysteine;

N-Acetylcysteine;

NSC 111180;

Neo-Fluimucil;

Nα-Acetylcysteine;

Parvolex;

Respaire;

Syntemucol;

Tixair;

Trom
Structure:

Related Targets  (Total: 29)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
A 2 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
A 1 Reference(s)
T67KTV Transient receptor potential cation channel subfamily V member 1TRPV1 Q8NER1
A 1 Reference(s)
T23P74 Caspase-9CASP9 P55211
A 1 Reference(s)
T67HAF Signal transducer and activator of transcription 1-alpha/betaSTAT1 P42224
A 1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
A 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
A 1 Reference(s)
T60GGR Serine/threonine-protein kinase TBK1TBK1 Q9UHD2
A 1 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
A 1 Reference(s)
T30KQB Alanine aminotransferase 1GPT P24298
A 1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
A 1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
A 2 Reference(s)
T28HCY Presenilin-1PSEN1 P49768
A 1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
A 1 Reference(s)
T40XWM Proto-oncogene tyrosine-protein kinase ROSROS1 P08922
A 1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
C 1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
C 1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
C 2 Reference(s)
T32TBL Short transient receptor potential channel 6TRPC6 Q9Y210
C 1 Reference(s)
T23HHS Eukaryotic peptide chain release factor subunit 1ETF1 P62495
C 1 Reference(s)
T91OUC Mucin-5ACMUC5AC P98088
C 1 Reference(s)
T84P70 Urokinase-type plasminogen activatorPLAU P00749
C 1 Reference(s)
T29WP4 Protransforming growth factor alpha [Cleaved into: Transforming growth factor alphaTGFA P01135
C 1 Reference(s)
T63RJO Growth arrest and DNA damage-inducible protein GADD45 betaGADD45B O75293
C 1 Reference(s)
T18A7W Very low-density lipoprotein receptorVLDLR P98155
C 1 Reference(s)
T71PEL Excitatory amino acid transporter 2SLC1A2 P43004
C 1 Reference(s)
T06ADX Tyrosine-protein kinase receptor UFOAXL P30530
C 1 Reference(s)
T20NCI Serine-protein kinase ATMATM Q13315
C 1 Reference(s)
T79TJS Caveolin-3CAV3 P56539
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0938 Da Suan大蒜 GarlicAllium sativum