HIT-result

Type	Detail
Target ID	T29WP4
Protein Name	Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha
Uniprot ID	P01135
Protein Name Alias	TGF-alpha; EGF-like TGF; ETGF; TGF type 1
Gene ID	7039
Gene Symbol	TGFA
Gene Alias	NA
TTD	T00033: Clinical Trial target
Pfam	NA
GO	0045741:positive regulation of epidermal growth factor-activated receptor activity 0042059:negative regulation of epidermal growth factor receptor signaling pathway 0006888:endoplasmic reticulum to Golgi vesicle-mediated transport 0035556:intracellular signal transduction 0000165:MAPK cascade 0005789:endoplasmic reticulum membrane 0009986:cell surface 0005615:extracellular space 0016021:integral component of membrane 0050679:positive regulation of epithelial cell proliferation 0061024:membrane organization 0007173:epidermal growth factor receptor signaling pathway 0016323:basolateral plasma membrane 0033116:endoplasmic reticulum-Golgi intermediate compartment membrane 0045840:positive regulation of mitotic nuclear division 0005576:extracellular region 0008083:growth factor activity 0005886:plasma membrane 0030669:clathrin-coated endocytic vesicle membrane 0048471:perinuclear region of cytoplasm 0008284:positive regulation of cell population proliferation 0005154:epidermal growth factor receptor binding 0051781:positive regulation of cell division 0000187:activation of MAPK activity 0007165:signal transduction 0048208:COPII vesicle coating 0012507:ER to Golgi transport vesicle membrane 0051897:positive regulation of protein kinase B signaling 0031410:cytoplasmic vesicle 0006357:regulation of transcription by RNA polymerase II
PDB	1MOX ; 5KN5 ; 4TGF ; 3E50 ; 1YUF ; 2TGF ; 1GK5 ; 1YUG ; 3TGF
Drugbank	NA
KEGG	hsa:7039

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0854	Zi Wei Gen Pi	紫葳根皮	NA	Campsis grandiflora
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0239	Bei Sha Shen	北沙参	Coastal glehnia	Glehnia littoralis
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0242	Bei Sha Shen Liu Jin Gao	北沙参流浸膏	Glehnia littoralis	Glehnia littoralis
H0119	La Jiao	辣椒	Bush redpepper	Capsicum frutescens
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0121	La Jiao Jin Chu Ye	辣椒浸出液	Bush redpepper	Capsicum frutescens
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0122	La Jiao Jin Gao	辣椒浸膏	Bush redpepper	Capsicum frutescens
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H0123	La Jiao Liu Jin Gao	辣椒流浸膏	Bush redpepper	Capsicum frutescens
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0416	Shan Shen	山参	NA	Panax ginseng
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 36)