Target Description

Type Detail
Target ID T13QI6
Protein Name Aldo-keto reductase family 1 member A1
Uniprot ID P14550
Protein Name Alias EC 1.1.1.2;  EC 1.1.1.372;  EC 1.1.1.54
Gene ID 10327
Gene Symbol AKR1A1
Gene Alias ALDR1;  ALR
TTD NA
Pfam PF00248
GO
0004032:alditol:NADP+ 1-oxidoreductase activity

0047655:allyl-alcohol dehydrogenase activity

0045202:synapse

1901687:glutathione derivative biosynthetic process

0042840:D-glucuronate catabolic process

0019853:L-ascorbic acid biosynthetic process

0006081:cellular aldehyde metabolic process

0006006:glucose metabolic process

0047939:L-glucuronate reductase activity

0070062:extracellular exosome

0005829:cytosol

0005615:extracellular space

0019640:glucuronate catabolic process to xylulose 5-phosphate

0110095:cellular detoxification of aldehyde

0047941:glucuronolactone reductase activity

1990002:methylglyoxal reductase (NADPH-dependent, acetol producing)

0047956:glycerol dehydrogenase [NADP+] activity

0044597:daunorubicin metabolic process

0044598:doxorubicin metabolic process

0046185:aldehyde catabolic process

0047834:D-threo-aldose 1-dehydrogenase activity

0009055:electron transfer activity

0016324:apical plasma membrane

PDB 2ALR
Drugbank DB09130 ; DB06077 ; DB03461 ; DB02383 ; DB00997 ; DB00898 ; DB08904 ; DB00157
KEGG hsa:10327

Related Compounds  (Total: 3)

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C0082
Name: Fomepizole
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C0337
Name: Puerarin
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C0867
Name: Alcohol


Related Herbs  (Total: 30)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0416 Shan Shen山参 NAPanax ginseng
H0714 Yan Tai Chai Hu烟台柴胡 Chinese thorowaxBupleurum chinense
H0685 Xuan Cao Gen萱草根 Orange daylilyHemerocallis fulva
H1254 Huang Qin Tan黄芩炭 Extract of root of Baikal skullcaapScutellaria baicalensis
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H1037 Fen Ge粉葛 Thomson kudzuvinePueraria thomsonii
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0659 Chai Hu Jin Gao柴胡浸膏 Chinese thorowaxBupleurum chinense
H0650 Chai Hu柴胡 Chinese thorowaxBupleurum chinense
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0938 Da Suan大蒜 GarlicAllium sativum
H0522 Tai Zi Shen太子参 Heterophylly falsestarwort rootRadix pseudostellariae
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H1251 Huang Qin黄芩 Root of Baikal skullcaapScutellaria baicalensis
H1253 Huang Qin Jin Gao Fen黄芩浸膏粉 Extract of root of Baikal skullcaapScutellaria baicalensis
H0310 Pian Qin片芩 Scutellaria amoenaScutellaria baicalensis
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0665 Chai Hu Shao柴胡梢 Chinese thorowaxBupleurum chinense
H0357 Ren Shen人参 GinsengPanax ginseng
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H1252 Huang Qin Jin Gao黄芩浸膏 Extract of root of Baikal skullcaapScutellaria baicalensis